The prolyl isomerase Pin1 stabilizes the human T-cell leukemia virus type 1 (HTLV-1) Tax oncoprotein and promotes malignant transformation.

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Biochemical and Biophysical Research Communications - BBRC

• Publication date

  2009-04-03

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.bbrc.2009.02.024PMID 19338781
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Peptidylproline cis-trans-Isomerase Pin1 Interacts with Human T-Cell Leukemia Virus Type 1 Tax and Modulates Its Activation of NF-κB

  2009cited by this paper
• Pin1-dependent Prolyl Isomerization Modulates the Stress-induced Phosphorylation of High Molecular Weight Neurofilament Protein*

  2008cited by this paper
• PI3K/AKT inhibition induces caspase-dependent apoptosis in HTLV-1-transformed cells.

  2008cited by this paper
• Human Immunodeficiency Virus Type 1 Replication and Regulation of APOBEC3G by Peptidyl Prolyl Isomerase Pin1

  2008cited by this paper
• Pin1 regulates TGF-beta1 production by activated human and murine eosinophils and contributes to allergic lung fibrosis.

  2008cited by this paper
• A Suppressive Role of the Prolyl Isomerase Pin1 in Cellular Apoptosis Mediated by the Death-associated Protein Daxx*

  2007cited by this paper
• Pin1 interacts with a specific serine-proline motif of hepatitis B virus X-protein to enhance hepatocarcinogenesis.

  2007cited by this paper
• Site-specific Phosphorylation Differentiates Active from Inactive Forms of the Human T-cell Leukemia Virus Type 1 Tax Oncoprotein*

  2006cited by this paper
• High Pin1 expression is associated with tumor progression in colorectal cancer

  2006cited by this paper
• Intracellular Protein Degradation and Its Therapeutic Implications

  2005cited by this paper
• Stable Ubiquitination of Human T-Cell Leukemia Virus Type 1 Tax Is Required for Proteasome Binding

  2004cited by this paper
• Ubiquitin‐dependent lysosomal degradation of the HNE‐modified proteins in lens epithelial cells

  2004cited by this paper
• Ubiquitination of Human T-Cell Leukemia Virus Type 1 Tax Modulates Its Activity

  2004cited by this paper
• HTLV-I Tax induces a novel interaction between p65/RelA and p53 that results in inhibition of p53 transcriptional activity.

  2004cited by this paper
• Prevalent overexpression of prolyl isomerase Pin1 in human cancers.

  2004cited by this paper
• Prolyl isomerase Pin1: a catalyst for oncogenesis and a potential therapeutic target in cancer

  2003cited by this paper
• Human T-cell leukemia virus type I and adult T-cell leukemia

  2003cited by this paper
• Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA.

  2003cited by this paper
• The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults

  2002cited by this paper
• Loss of Pin1 function in the mouse causes phenotypes resembling cyclin D1-null phenotypes

  2002cited by this paper
• Pinning down proline-directed phosphorylation signaling.

  2002cited by this paper
• The ubiquitin system

  2000cited by this paper
• The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein

  1999cited by this paper
• The ubiquitin system.

  1998cited by this paper
• Effects on NF-κB1/p105 processing of the interaction between the HTLV-1 transactivator Tax and the proteasome

  1996cited by this paper
• Characterization of T cells immortalized by Tax1 of human T-cell leukemia virus type 1.

  1995cited by this paper
• Mutational analysis of human T-cell leukemia virus type I Tax: regions necessary for function determined with 47 mutant proteins

  1992cited by this paper
• Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma

  1980cited by this paper

• Pin1-Catalyzed Conformation Changes Regulate Protein Ubiquitination and Degradation

  2024cites this paper
• Understanding the Cytomegalovirus Cyclin-Dependent Kinase Ortholog pUL97 as a Multifaceted Regulator and an Antiviral Drug Target

  2024cites this paper
• Pin1: Advances in pancreatic cancer therapeutic potential and inhibitors research.

  2024cites this paper
• Pin1-catalyzed conformational regulation after phosphorylation: A distinct checkpoint in cell signaling and drug discovery

  2024cites this paper
• The HTLV-I oncoprotein Tax inactivates the tumor suppressor FBXW7

  2024cites this paper
• SARS‐CoV‐2, periodontal pathogens, and host factors: The trinity of oral post‐acute sequelae of COVID‐19

  2024cites this paper
• Biological Function of Pin1 in Vivo and Its Inhibitors for Preclinical Study: Early Development, Current Strategies, and Future Directions.

  2023cites this paper
• Peptidyl-prolyl cis/trans isomerase Pin1 interacts with hepatitis B virus core particle, but not with HBc protein, to promote HBV replication

  2023cites this paper
• Roles of peptidyl prolyl isomerase Pin1 in viral propagation

  2022influential citation
• Roles of peptidyl-prolyl isomerase Pin1 in disease pathogenesis

  2021influential citation
• Prolyl isomerase Pin1 plays an essential role in SARS-CoV-2 proliferation, indicating its possibility as a novel therapeutic target

  2021cites this paper
• Targeting PIN-1 Attenuates GCB DLBCL Cell Proliferation Through Inhibition of PI3K/AKT Signaling

  2020cites this paper
• OTT_A_247429 8593..8600

  2020cites this paper
• Prolyl Isomerase Pin1 Regulates the Stability of Hepatitis B Virus Core Protein

  2020cites this paper
• BCR‐ABL enhances the prolyl isomerase activity of Pin 1 by interacting with DAPK1 in ph+ ALL

  2018cites this paper
• Host-Driven Phosphorylation Appears to Regulate the Budding Activity of the Lassa Virus Matrix Protein

  2018cites this paper
• The Roles of the Unique Prolyl Isomerase Pin1 in Cancer-Related Viral and Bacterial Infections.

  2016cites this paper
• Overexpression of PIN1 Enhances Cancer Growth and Aggressiveness with Cyclin D1 Induction in EBV-Associated Nasopharyngeal Carcinoma

  2016cites this paper
• The isomerase PIN1 controls numerous cancer-driving pathways and is a unique drug target

  2016cites this paper
• Roles of HTLV-1 basic Zip Factor (HBZ) in Viral Chronicity and Leukemic Transformation. Potential New Therapeutic Approaches to Prevent and Treat HTLV-1-Related Diseases

  2015cites this paper
• In Vitro Functional Comparisons of HTLV-1 HBZ and HTLV-2 APH-2: Implications for Viral Persistence and Pathobiology

  2014cites this paper
• Identification and Characterization of HTLV-1 HBZ Post-Translational Modifications

  2014cites this paper
• Role of prolyl isomerase pin1 in pathogenesis of diseases and remedy for the diseases from natural products.

  2014cites this paper
• Tax-1 and Tax-2 similarities and differences: focus on post-translational modifications and NF-κB activation

  2013cites this paper
• Insights into the Roles of Cyclophilin A During Influenza Virus Infection

  2013cites this paper
• Cyclophilin A Restricts Influenza A Virus Replication through Degradation of the M1 Protein

  2012cites this paper
• Pin1 Interacts with the Epstein-Barr Virus DNA Polymerase Catalytic Subunit and Regulates Viral DNA Replication

  2012cites this paper
• Human T-lymphotropic virus proteins and post-translational modification pathways.

  2012cites this paper
• Human T-cell leukemia virus type 1 (HTLV-1) and leukemic transformation: viral infectivity, Tax, HBZ and therapy

  2011cites this paper
• Move or Die: the Fate of the Tax Oncoprotein of HTLV-1

  2011cites this paper
• Peptidyl-Prolyl Isomerase Pin1 Is a Cellular Factor Required for Hepatitis C Virus Propagation

  2011cites this paper
• Human T-Cell Lymphotropic Virus: A Model of NF-κB-Associated Tumorigenesis

  2011cites this paper
• Prolyl isomerase Pin1 as a molecular switch to determine the fate of phosphoproteins.

  2011cites this paper
• Prolyl cis/trans isomerase signalling pathways in cancer.

  2011cites this paper
• Intracellular Localization and Cellular Factors Interaction of HTLV-1 and HTLV-2 Tax Proteins: Similarities and Functional Differences

  2011cites this paper
• HTLV-1 and adult T-cell leukemia: insights into viral transformation of cells 30 years after virus discovery.

  2010cites this paper
• Pinning Down Viral Proteins: A New Prototype for Virus–Host Cell Interaction

  2010cites this paper
• Pin1 Catalyzes Conformational Changes of Thr-187 in p27Kip1 and Mediates Its Stability through a Polyubiquitination Process*

  2009cites this paper