Rationale The CANTAB object-location paired-associate learning (PAL) test can detect cognitive deficits in schizophrenia and Alzheimer’s disease. A rodent version of touch screen PAL (dPAL) has been developed, but the underlying neural mechanisms are not fully understood. Although there is evidence that inactivation of the hippocampus following training leads to impairments in rats, this has not been tested in mice. Furthermore, it is not known whether acquisition, as opposed to performance, of the rodent version depends on the hippocampus. This is critical as many mouse models may have hippocampal dysfunction prior to the onset of task training.
Erratum to: The role of the dorsal hippocampus in two versions of the touchscreen automated paired associates learning (PAL) task for mice
C. Kim,C. J. Heath,Brianne A. Kent,Alexa E. Horner,T. Bussey,L. Saksida
Published 2015 in Psychopharmacology
ABSTRACT
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- Publication year
2015
- Venue
Psychopharmacology
- Publication date
2015-05-13
- Fields of study
Biology, Medicine, Psychology
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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