The coding sequence mediates induction of 5-lipoxygenase expression by Smads3/4.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Biochemical and Biophysical Research Communications - BBRC

• Publication date

  2006-10-06

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/J.BBRC.2006.08.011PMID 16919603
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Analysis of the 5-lipoxygenase promoter and characterization of a vitamin D receptor binding site.

  2006cited by this paper
• Regulation of 5-lipoxygenase enzyme activity.

  2005cited by this paper
• Smad transcription factors.

  2005cited by this paper
• Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits

  2005cited by this paper
• The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke

  2004cited by this paper
• Differential Activation of Smads in HeLa and SiHa Cells That Differ in Their Response to Transforming Growth Factor-β*

  2004cited by this paper
• 5-Lipoxygenase and atherosclerosis

  2003cited by this paper
• Trichostatin A and Structurally Related Histone Deacetylase Inhibitors Induce 5-Lipoxygenase Promoter Activity

  2003cited by this paper
• The 5-Lipoxygenase Promoter Is Regulated by DNA Methylation*

  2002cited by this paper
• 1,25-(OH(2))D(3) alters the transforming growth factor beta signaling pathway in renal tissue.

  2001cited by this paper
• The Smads

  2001cited by this paper
• 1,25-(OH2)D3 Alters the Transforming Growth Factor β Signaling Pathway in Renal Tissue

  2001cited by this paper
• Autocrine TGFβ signaling mediates vitamin D3 analog‐induced growth inhibition in breast cells

  2001cited by this paper
• How cells read TGF-β signals

  2000cited by this paper
• How cells read TGF-beta signals.

  2000cited by this paper
• Positive and Negative Modulation of Vitamin D Receptor Function by Transforming Growth Factor-β Signaling through Smad Proteins*

  1999cited by this paper
• Transcriptional and posttranscriptional regulation of 5-lipoxygenase mRNA expression in the human monocytic cell line Mono Mac 6 by transforming growth factor-beta and 1,25-dihydroxyvitamin D3.

  1999cited by this paper
• 5-Lipoxygenase: a target for antiinflammatory drugs revisited.

  1999cited by this paper
• Regulation of 5-Lipoxygenase mRNA Expression in the Human Monocytic Cell Line Mono Mac 6 by Transforming Growth Factor-ß and 1,25-Dihydroxyvitamin D 3

  1999cited by this paper
• Calcitriol and transforming growth factor-beta upregulate 5-lipoxygenase mRNA expression by increasing gene transcription and mRNA maturation.

  1998cited by this paper
• Quantification of gene expression with a secreted alkaline phosphatase reporter system.

  1997cited by this paper
• Dual luminescence-based reporter gene assay for luciferase and beta-galactosidase.

  1996cited by this paper
• Purification of transforming growth factor beta 1 from human platelets.

  1996cited by this paper
• Dual Luminescence-Based Reporter Gene Assay for Luciferase andβ-Galactosidase

  1996cited by this paper
• Interleukin-3 Regulates Development of the 5-Lipoxygenase/Leukotriene C4 Synthase Pathway in Mouse Mast Cells (*)

  1995cited by this paper
• Sequential induction of 5-lipoxygenase gene expression and activity in Mono Mac 6 cells by transforming growth factor beta and 1,25-dihydroxyvitamin D3.

  1995cited by this paper
• On the induction of 5-lipoxygenase expression and activity in HL-60 cells: effects of vitamin D3, retinoic acid, DMSO and TGF beta.

  1994cited by this paper
• Identification of a TGF-beta responsive element in the human elastin promoter.

  1994cited by this paper
• Identification of a TGF-β Responsive Element in the Human Elastin Promoter

  1994cited by this paper
• Mutagenesis of some conserved residues in human 5-lipoxygenase: Effects on enzyme activity

  1992cited by this paper
• Mutagenesis of some conserved residues in human 5-lipoxygenase: effects on enzyme activity.

  1992cited by this paper
• Granulocyte-macrophage colony-stimulating factor increases the synthesis of leukotriene B4 by human neutrophils in response to platelet-activating factor. Enhancement of both arachidonic acid availability and 5-lipoxygenase activation.

  1991cited by this paper
• Establishment of a human cell line (mono mac 6) with characteristics of mature monocytes

  1988cited by this paper

• LPS induces ALOX5 promoter activation and 5-lipoxygenase expression in human monocytic cells.

  2020cites this paper
• Vitamin D modulates E-cadherin turnover by regulating TGF-β and Wnt signalings during EMT-mediated myofibroblast differentiation in A459 cells.

  2020cites this paper
• Phenotypically-Silent Bone Morphogenetic Protein Receptor 2 (Bmpr2) Mutations Predispose Rats to Inflammation-Induced Pulmonary Arterial Hypertension by Enhancing The Risk for Neointimal Transformation.

  2019cites this paper
• Beyond leukotriene formation-The noncanonical functions of 5-lipoxygenase.

  2019cites this paper
• Phenotypically Silent Bone Morphogenetic Protein Receptor 2 Mutations Predispose Rats to Inflammation- Induced Pulmonary Arterial Hypertension by Enhancing the Risk for Neointimal Transformation

  2019cites this paper
• Apoptotic Cancer Cells Suppress 5-Lipoxygenase in Tumor-Associated Macrophages

  2018cites this paper
• TGFβ/SMAD signalling modulates MLL and MLL-AF4 mediated 5-lipoxygenase promoter activation.

  2017cites this paper
• AF4 and AF4-MLL mediate transcriptional elongation of 5-lipoxygenase mRNA by 1, 25-dihydroxyvitamin D3

  2015cites this paper
• 5-Lipoxygenase Is a Direct Target of miR-19a-3p and miR-125b-5p

  2015cites this paper
• Binding of a Smad4/Ets-1 complex to a novel intragenic regulatory element in exon12 of FPGS underlies decreased gene expression and antifolate resistance in leukemia

  2014cites this paper
• Inhibition of class I HDACs abrogates the dominant effect of MLL-AF4 by activation of wild-type MLL

  2014cites this paper
• CD69 Is a TGF-β/1α,25-dihydroxyvitamin D3 Target Gene in Monocytes

  2013cites this paper
• Contrôle physiologique et pharmacologique de la biosynthèse des leucotriènes

  2012cites this paper
• Transforming growth factor β1-induced astrocyte migration is mediated in part by activating 5-lipoxygenase and cysteinyl leukotriene receptor 1

  2012cites this paper
• Trichostatin A induces 5-lipoxygenase promoter activity and mRNA expression via inhibition of histone deacetylase 2 and 3

  2012cites this paper
• Novel 5‐lipoxygenase isoforms affect the biosynthesis of 5‐lipoxygenase products

  2011cites this paper
• Regulation of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase-activating protein/5-lipoxygenase by 4-hydroxynonenal in human osteoarthritic chondrocytes

  2010cites this paper
• Calcitriol upregulates open chromatin and elongation markers at functional vitamin D response elements in the distal part of the 5-lipoxygenase gene.

  2010cites this paper
• 5-Lipoxygenase : mechanisms of regulation 1

  2009cites this paper
• 5-Lipoxygenase: mechanisms of regulation 1

  2009cites this paper
• Functional characterization of vitamin D responding regions in the human 5-Lipoxygenase gene.

  2007cites this paper
• 5-Lipoxygenase: regulation of expression and enzyme activity.

  2007cites this paper
• Biosynthesis and metabolism of leukotrienes.

  2007cites this paper
• miR-19a-3p and miR-125b-5p 5-Lipoxygenase Is a Direct Target of

  year unknowncites this paper