Differential regulation of survivin by p53 contributes to cell cycle dependent apoptosis

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Cell Research

• Publication date

  2005-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/sj.cr.7290303PMID 15916722
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Acute Ablation of Survivin Uncovers p53-dependent Mitotic Checkpoint Functions and Control of Mitochondrial Apoptosis*

  2004cited by this paper
• Survivin is required for a sustained spindle checkpoint arrest in response to lack of tension

  2003cited by this paper
• p21/CDKN1A Mediates Negative Regulation of Transcription by p53*

  2003cited by this paper
• The Role of TP 53 in Cervical Carcinogenesis

  2003cited by this paper
• A mediates negative regulation of transcription by p 53

  2003cited by this paper
• The role of TP53 in Cervical carcinogenesis

  2003cited by this paper
• Survivin, versatile modulation of cell division and apoptosis in cancer

  2003cited by this paper
• Cell cycle and apoptosis

  2003cited by this paper
• Induction of mitochondrion-mediated apoptosis of CHO cells by tripchloro- lide

  2003cited by this paper
• c-Myc degradation induced by DNA damage results in apoptosis of CHO cells

  2003cited by this paper
• A novel assay for discovery and characterization of pro-apoptotic drugs and for monitoring apoptosis in patient sera

  2003cited by this paper
• Human survivin is negatively regulated by wild-type p53 and participates in p53-dependent apoptotic pathway

  2002cited by this paper
• Antiproliferative and proapoptotic activities of triptolide (PG490), a natural product entering clinical trials, on primary cultures of human prostatic epithelial cells.

  2002cited by this paper
• Transcriptional Repression of the Anti-apoptoticsurvivin Gene by Wild Type p53*

  2002cited by this paper
• c-Myc Is Necessary for DNA Damage-Induced Apoptosis in the G2 Phase of the Cell Cycle

  2001cited by this paper
• p53 modulates base excision repair activity in a cell cycle-specific manner after genotoxic stress.

  2001cited by this paper
• Staurosporine-induced apoptosis of HPV positive and negative human cervical cancer cells from different points in the cell cycle

  2001cited by this paper
• Functional p53 is required for triptolide-induced apoptosis and AP-1 and nuclear factor-κB activation in gastric cancer cells

  2001cited by this paper
• P53-responsive genes and the potential for cancer diagnostics and therapeutics development.

  2001cited by this paper
• Kinetics of p53 Binding to Promoter Sites In Vivo

  2001cited by this paper
• Anti-inflammatory effects of triptolide in human bronchial epithelial cells.

  2000cited by this paper
• Activation of p53 in cervical carcinoma cells by small molecules.

  2000cited by this paper
• Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2.

  2000cited by this paper
• Sensitivity of myelomonocytic leukemia cells to arsenite-induced cell cycle disruption, apoptosis, and enhanced differentiation is dependent on the inter-relationship between arsenic concentration, duration of treatment, and cell cycle phase.

  2000cited by this paper
• Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin.

  2000cited by this paper
• Surfing the p53 network

  2000cited by this paper
• Repression of human papillomavirus oncogenes in HeLa cervical carcinoma cells causes the orderly reactivation of dormant tumor suppressor pathways.

  2000cited by this paper
• Immunosuppressant PG490 (Triptolide) Inhibits T-cell Interleukin-2 Expression at the Level of Purine-box/Nuclear Factor of Activated T-cells and NF-κB Transcriptional Activation*

  1999cited by this paper
• PG490 (Triptolide) Cooperates with Tumor Necrosis Factor-α to Induce Apoptosis in Tumor Cells*

  1999cited by this paper
• Immunocytochemical detection and mapping of a cytokeratin 18 neo‐epitope exposed during early apoptosis

  1999cited by this paper
• A role for ATR in the DNA damage-induced phosphorylation of p53.

  1999cited by this paper
• Control of apoptosis and mitotic spindle checkpoint by survivin

  1998cited by this paper
• Apoptosis detection: an overview.

  1998cited by this paper
• The p53 Network*

  1998cited by this paper
• A link between cell cycle and cell death: Bax and Bcl‐2 modulate Cdk2 activation during thymocyte apoptosis

  1998cited by this paper
• Expression of a novel antiapoptosis gene, survivin, correlated with tumor cell apoptosis and p53 accumulation in gastric carcinomas.

  1998cited by this paper
• The inhibitors of apoptosis (IAPs) and their emerging role in cancer

  1998cited by this paper
• Evaluation of the mutagenic, cytotoxic, and antitumor potential of triptolide, a highly oxygenated diterpene isolated from Tripterygium wilfordii.

  1997cited by this paper
• DNA damage induces phosphorylation of the amino terminus of p53.

  1997cited by this paper
• Cloning and characterization of Chinese hamster p53 cDNA.

  1997cited by this paper
• Suppression of Apoptosis by Dominant Negative Mutants of Cyclin-dependent Protein Kinases (*)

  1996cited by this paper
• A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V.

  1995cited by this paper
• p53-dependent G1 arrest involves pRB-related proteins and is disrupted by the human papillomavirus 16 E7 oncoprotein.

  1994cited by this paper
• Activation of cyclin A-dependent protein kinases during apoptosis.

  1994cited by this paper
• The cell cycle related differences in susceptibility of HL-60 cells to apoptosis induced by various antitumor agents.

  1993cited by this paper
• The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53.

  1993cited by this paper
• p53-mediated cell death: relationship to cell cycle control

  1993cited by this paper
• [Structure modification of triptolide, a diterpenoid from Tripterygium wilfordii].

  1992cited by this paper
• [Structure modification of triptolide, a diterpenoid from Tripterygium wilfordii].

  1992cited by this paper
• Inhibitory effect of triptolide on colony formation of breast and stomach cancer cell lines.

  1991cited by this paper
• Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2

  1990cited by this paper

• A novel Gboxin analog induces OXPHOS inhibition and mitochondrial dysfunction-mediated apoptosis in diffuse large B-cell lymphoma.

  2022cites this paper
• Immunohistochemical evaluation of survivin in oral lichen planus and oral squamous cell carcinoma - a retrospective study

  2021cites this paper
• Therapeutic potential of p53 reactivation in cervical cancer.

  2020cites this paper
• IFI16 promotes human embryonic stem cell trilineage specification through interaction with p53

  2020cites this paper
• Targeting the mevalonate pathway is a novel therapeutic approach to inhibit oncogenic FoxM1 transcription factor in human hepatocellular carcinoma

  2018cites this paper
• Synergy between Prkdc and Trp53 regulates stem cell proliferation and GI-ARS after irradiation

  2017cites this paper
• Inhibition of antiviral drug cidofovir on proliferation of human papillomavirus-infected cervical cancer cells

  2016cites this paper
• Developing Michigan Cancer Foundation 7 Cells with Stable Expression of E7 Gene of Human Papillomavirus Type 16

  2016cites this paper
• Comparison of the Radiosensitizing Effect of ATR, ATM and DNA-PK Kinase Inhibitors on Cervical Carcinoma Cells.

  2016cites this paper
• The Isomer ΔASPP2 Abrogates ASPP2-promoted p53 Apoptosis

  2012cites this paper
• Anti-proliferative and apoptotic effects of the derivatives from 4-aryl-4H-chromene family on human leukemia K562 cells

  2012cites this paper
• Innovative Ansätze in der Diagnostik und Therapie gastrointestinaler Tumore

  2010cites this paper
• Bexarotene activates the p53/p73 pathway in human cutaneous T‐cell lymphoma

  2009cites this paper
• Involvement of multiple signaling pathways in diallyl sulfide mediated apoptosis in mouse skin tumors.

  2006cites this paper
• p53-independent pRB degradation contributes to a drug-induced apoptosis in AGS cells

  2005cites this paper