Control activity of yeast geranylgeranyl diphosphate synthase from dimer interface through H-bonds and hydrophobic interaction.

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Biochemistry

• Publication date

  2013-04-11

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1021/bi4001276PMID 23534508
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Roles of amino acids in the Escherichia coli octaprenyl diphosphate synthase active site probed by structure-guided site-directed mutagenesis.

  2012cited by this paper
• Strategies in the design of antiviral drugs

  2010cited by this paper
• Combined experimental and theoretical study of long-range interactions modulating dimerization and activity of yeast geranylgeranyl diphosphate synthase.

  2009cited by this paper
• Reaction kinetics, catalytic mechanisms, conformational changes, and inhibitor design for prenyltransferases.

  2009cited by this paper
• Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases

  2007cited by this paper
• Structure and reaction geometry of geranylgeranyl diphosphate synthase from Sinapis alba.

  2006cited by this paper
• The Crystal Structure of Human Geranylgeranyl Pyrophosphate Synthase Reveals a Novel Hexameric Arrangement and Inhibitory Product Binding*

  2006cited by this paper
• Crystal Structure of Type-III Geranylgeranyl Pyrophosphate Synthase from Saccharomyces cerevisiae and the Mechanism of Product Chain Length Determination*

  2006cited by this paper
• Homodimeric Hexaprenyl Pyrophosphate Synthase from the Thermoacidophilic Crenarchaeon Sulfolobus solfataricus Displays Asymmetric Subunit Structures

  2005cited by this paper
• Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: Implications for drug design

  2005cited by this paper
• Crystal Structure of Octaprenyl Pyrophosphate Synthase from Hyperthermophilic Thermotoga maritima and Mechanism of Product Chain Length Determination*

  2004cited by this paper
• Structural Basis for Bisphosphonate-mediated Inhibition of Isoprenoid Biosynthesis*

  2004cited by this paper
• Strategies in the design of antiviral drugs

  2002cited by this paper
• Gibberellin Signaling Article, publication date, and citation information can be found at www.plantcell.org/cgi/doi/10.1105/tpc.010476.

  2002cited by this paper
• Human Geranylgeranyl Diphosphate Synthase

  1999cited by this paper
• Enzymatic Aspects of Isoprenoid Chain Elongation.

  1998cited by this paper
• Creating Isoprenoid Diversity

  1997cited by this paper
• BTS1 Encodes a Geranylgeranyl Diphosphate Synthase in Saccharomyces cerevisiae(*)

  1995cited by this paper
• Isoprenyl diphosphate synthases: Protein sequence comparisons, a phylogenetic tree, and predictions of secondary structure

  1994cited by this paper
• Crystal structure of recombinant farnesyl diphosphate synthase at 2.6-A resolution.

  1994cited by this paper
• Protein isoprenylation and methylation at carboxyl-terminal cysteine residues.

  1992cited by this paper
• Carotenoid biosynthesis: Isolation and characterization of a bifunctional enzyme catalyzing the synthesis of phytoene.

  1988cited by this paper
• Detection and partial characterization of activity of chlorophyll synthetase in etioplast membranes.

  1980cited by this paper
• Interaction of an apolipoprotein (apoLP-alanine) with phosphatidylcholine.

  1973cited by this paper

• Structures of Mycobacterium tuberculosis isoprenyl diphosphate synthase Rv2173 in substrate-bound forms

  2025cites this paper
• Characterisation of lepidopteran geranylgeranyl diphosphate synthase as a putative pesticide target

  2023cites this paper
• Cloning and functional characterization of the geranylgeranyl diphosphate synthase(GGPPS)from Elizabethkingia meningoseptica sp.F2.

  2021cites this paper