Thioredoxin inhibits MPK38-induced ASK1, TGF-β, and p53 function in a phosphorylation-dependent manner.

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Free Radical Biology & Medicine

• Publication date

  2013-10-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.freeradbiomed.2013.05.020PMID 23747528
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Thioredoxin

  2020cited by this paper
• Thioredoxin and glutaredoxin systems.

  2019cited by this paper
• Thioredoxin-1 functions as a molecular switch regulating the oxidative stress-induced activation of MST1.

  2012cited by this paper
• Murine Protein Serine-threonine Kinase 38 Activates p53 Function through Ser15 Phosphorylation*

  2012cited by this paper
• Positive Regulation of Apoptosis Signal-regulating Kinase 1 Signaling by ZPR 9 , a Zinc Finger Protein

  2011cited by this paper
• Positive Regulation of Apoptosis Signal-regulating Kinase 1 Signaling by ZPR9 Protein, a Zinc Finger Protein*

  2011cited by this paper
• Thioredoxin-1 phosphorylated at T100 is needed for its anti-apoptotic activity in HepG2 cancer cells.

  2010cited by this paper
• Murine Protein Serine/Threonine Kinase 38 Stimulates TGF-β Signaling in a Kinase-dependent Manner via Direct Phosphorylation of Smad Proteins*

  2010cited by this paper
• Apoptosis signal-regulating kinase 1 mediates denbinobin-induced apoptosis in human lung adenocarcinoma cells

  2009cited by this paper
• Serine-Threonine Kinase Receptor-associated Protein Inhibits Apoptosis Signal-regulating Kinase 1 Function through Direct Interaction*

  2009cited by this paper
• Thrombin-Induced Connective Tissue Growth Factor Expression in Human Lung Fibroblasts Requires the ASK1/JNK/AP-1 Pathway1

  2009cited by this paper
• Murine Protein Serine/Threonine Kinase 38 Activates Apoptosis Signal-regulating Kinase 1 via Thr838 Phosphorylation*

  2008cited by this paper
• 3-Phosphoinositide-dependent PDK1 Negatively Regulates Transforming Growth Factor-β-induced Signaling in a Kinase-dependent Manner through Physical Interaction with Smad Proteins*

  2007cited by this paper
• NM23-H1 Tumor Suppressor Physically Interacts with Serine-Threonine Kinase Receptor-associated Protein, a Transforming Growth Factor-β (TGF-β) Receptor-interacting Protein, and Negatively Regulates TGF-β Signaling*

  2007cited by this paper
• NM23-H1 tumor suppressor physically interacts with serine-threonine kinase receptor-associated protein, a transforming growth factor-beta (TGF-beta) receptor-interacting protein, and negatively regulates TGF-beta signaling.

  2007cited by this paper
• NM23-H1 Tumor Suppressor and Its Interacting Partner STRAP Activate p53 Function*

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• Redox-regulated cochaperone activity of the human DnaJ homolog Hdj2.

  2006cited by this paper
• Maternal embryonic leucine zipper kinase/murine protein serine-threonine kinase 38 is a promising therapeutic target for multiple cancers.

  2005cited by this paper
• Substrate Specificity and Activity Regulation of Protein Kinase MELK*

  2005cited by this paper
• Melk-Like Kinase Plays a Role in Hematopoiesis in the Zebra Fish

  2005cited by this paper
• Direct association of hepatopoietin with thioredoxin constitutes a redox signal transduction in activation of AP-1/NF-kappaB.

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• Thioredoxin and its role in toxicology.

  2004cited by this paper
• Inhibition of Spliceosome Assembly by the Cell Cycle-regulated Protein Kinase MELK and Involvement of Splicing Factor NIPP1*

  2004cited by this paper
• Thioredoxin modulates activator protein 1 (AP-1) activity and p27Kip1 degradation through direct interaction with Jab1

  2004cited by this paper
• Redox regulation of PI 3‐kinase signalling via inactivation of PTEN

  2003cited by this paper
• Enhancement of B-MYB Transcriptional Activity by ZPR9, a Novel Zinc Finger Protein*

  2003cited by this paper
• C-propeptide region of human pro alpha 1 type 1 collagen interacts with thioredoxin.

  2002cited by this paper
• C-propeptide region of human pro α 1 type 1 collagen interacts with thioredoxin

  2002cited by this paper
• Phosphorylation of a novel zinc-finger-like protein, ZPR9, by murine protein serine/threonine kinase 38 (MPK38).

  2002cited by this paper
• Thioredoxin Promotes ASK1 Ubiquitination and Degradation to Inhibit ASK1-Mediated Apoptosis in a Redox Activity-Independent Manner

  2002cited by this paper
• Thioredoxin Promotes ASK1 Ubiquitination and Degradation to Inhibit ASK1-Mediated Apoptosis in a Redox Activity-Independent Manner

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• Properties and biological activities of thioredoxins.

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• Direct Association with Thioredoxin Allows Redox Regulation of Glucocorticoid Receptor Function*

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  1999cited by this paper
• Identification of Thioredoxin-binding Protein-2/Vitamin D3 Up-regulated Protein 1 as a Negative Regulator of Thioredoxin Function and Expression*

  1999cited by this paper
• Mammalian thioredoxin is a direct inhibitor of apoptosis signal‐regulating kinase (ASK) 1

  1998influential reference
• Cloning and expression of a cDNA encoding a novel protein serine/threonine kinase predominantly expressed in hematopoietic cells.

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• New member of the Snf1/AMPK kinase family, Melk, is expressed in the mouse egg and preimplantation embryo

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• Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

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• Beyond Antioxidants: How Redox Pathways Shape Cellular Signaling and Disease Outcomes

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• Thioredoxin (Trx): A redox target and modulator of cellular senescence and aging-related diseases

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• Exosomal long non-coding RNAs: novel molecules in gastrointestinal cancers’ progression and diagnosis

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