Solution structure of the DFF-C domain of DFF45/ICAD. A structural basis for the regulation of apoptotic DNA fragmentation.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Journal of Molecular Biology

• Publication date

  2002-08-09

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/S0022-2836(02)00588-0PMID 12144788
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2002influential reference
• Solution structure of DFF40 and DFF45 N-terminal domain complex and mutual chaperone activity of DFF40 and DFF45

  2001cited by this paper
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  2000cited by this paper
• Characterization of the Rat DNA Fragmentation Factor 35/Inhibitor of Caspase-activated DNase (Short Form)

  2000cited by this paper
• Identification and Developmental Expression of Inhibitor of Caspase-activated DNase (ICAD) in Drosophila melanogaster*

  2000cited by this paper
• Antiproliferative effects of trapidil in vascular smooth muscle cells are associated by inhibition of MAPK and P34(cdc2) activity.

  2000cited by this paper
• Specific Chaperone-like Activity of Inhibitor of Caspase-activated DNase for Caspase-activated DNase*

  2000cited by this paper
• Structure of the heterodimeric complex between CAD domains of CAD and ICAD

  2000cited by this paper
• Differential localization of ICAD-L and ICAD-S in cells due to removal of a C-terminal NLS from ICAD-L by alternative splicing.

  2000cited by this paper
• Identification of Regulatory and Catalytic Domains in the Apoptosis Nuclease DFF40/CAD*

  1999cited by this paper
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  1999influential reference
• Protein backbone angle restraints from searching a database for chemical shift and sequence homology

  1999cited by this paper
• Functional Interaction of DFF35 and DFF45 with Caspase-activated DNA Fragmentation Nuclease DFF40*

  1999cited by this paper
• Multiple domains of DFF45 bind synergistically to DFF40: roles of caspase cleavage and sequestration of activator domain of DFF40.

  1999cited by this paper
• Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis

  1998cited by this paper
• A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

  1998cited by this paper
• Measurement of J and dipolar couplings from simplified two-dimensional NMR spectra.

  1998cited by this paper
• A robust method for determining the magnitude of the fully asymmetric alignment tensor of oriented macromolecules in the absence of structural information.

  1998influential reference
• Tunable alignment of macromolecules by filamentous phage yields dipolar coupling interactions

  1998cited by this paper
• Crystallography & NMR system: A new software suite for macromolecular structure determination.

  1998cited by this paper
• CIDE, a novel family of cell death activators with homology to the 45 kDa subunit of the DNA fragmentation factor

  1998influential reference
• Resistance to DNA fragmentation and chromatin condensation in mice lacking the DNA fragmentation factor 45.

  1998cited by this paper
• Programmed cell death in animal development.

  1997cited by this paper
• DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis.

  1997cited by this paper
• Torsion-angle molecular dynamics as a new efficient tool for NMR structure calculation.

  1997cited by this paper
• AQUA and PROCHECK-NMR: Programs for checking the quality of protein structures solved by NMR

  1996cited by this paper
• MOLMOL: a program for display and analysis of macromolecular structures.

  1996cited by this paper
• NMRPipe: A multidimensional spectral processing system based on UNIX pipes

  1995cited by this paper
• Backbone dynamics of Escherichia coli ribonuclease HI: correlations with structure and function in an active enzyme.

  1995cited by this paper
• Solution structure of a de novo helical protein by 2D-NMR spectroscopy.

  1994influential reference
• NMR View: A computer program for the visualization and analysis of NMR data

  1994cited by this paper
• Protein structure comparison by alignment of distance matrices.

  1993cited by this paper
• Methodological advances in protein NMR

  1993influential reference
• Primary structure effects on peptide group hydrogen exchange

  1993cited by this paper
• A biochemical hallmark of apoptosis: Internucleosomal degradation of the genome

  1992cited by this paper
• Determination of three-dimensional structures of proteins by simulated annealing with interproton distance restraints. Application to crambin, potato carboxypeptidase inhibitor and barley serine proteinase inhibitor 2.

  1988cited by this paper
• Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and dependence on macromolecular synthesis

  1984cited by this paper
• Dictionary of protein secondary structure: Pattern recognition of hydrogen‐bonded and geometrical features

  1983cited by this paper
• Programmed cell death.

  1974cited by this paper
• Primary structure effects on peptide group hydrogen exchange.

  1972cited by this paper

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  2020cites this paper
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  2018cites this paper
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  2017cites this paper
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  2017cites this paper
• DNA fragmentation factors 40 and 45 (DFF40/DFF45) and B-cell lymphoma 2 (Bcl-2) protein are underexpressed in uterine leiomyosarcomas and may predict survival

  2017influential citation
• Profiles of teleost DNA fragmentation factor alpha and beta from rock bream (Oplegnathus fasciatus): molecular characterization and genomic structure and gene expression in immune stress

  2016cites this paper
• Fragment Assembly Approach Based on Graph/Network Theory with Quantum Chemistry Verifications for Assigning Multidimensional NMR Signals in Metabolite Mixtures.

  2016cites this paper
• Physics-based potentials for the coupling between backbone- and side-chain-local conformational states in the UNited RESidue (UNRES) force field for protein simulations.

  2015cites this paper
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• Engineering of TEV Protease for Manipulation of Biosystems

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  2013cites this paper
• Improvement of the treatment of loop structures in the UNRES force field by inclusion of coupling between backbone- and side-chain-local conformational states.

  2013cites this paper
• When a domain is not a domain, and why it is important to properly filter proteins in databases

  2012cites this paper
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• Identification of ICAD‐derived peptides capable of inhibiting caspase‐activated DNase

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• DFF45 Expression in Human Endometrium Is Associated with Menstrual Cycle Phases and Decreases after Menopause

  2012cites this paper
• An improved functional form for the temperature scaling factors of the components of the mesoscopic UNRES force field for simulations of protein structure and dynamics.

  2009cites this paper
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  2009influential citation
• Practical aspects of uniform stable isotope labeling of higher plants for heteronuclear NMR-based metabolomics.

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• Phylogenomics of caspase-activated DNA fragmentation factor.

  2007cites this paper
• Computer‐aided NMR assay for detecting natively folded structural domains

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