Transmissible gastroenteritis coronavirus: surface antigens induced by virulent and attenuated strains

Summary Three strains of the transmissible gastroenteritis virus (TGEV) possessing different degrees of pathogenicity for piglets were examined for their capacity to express M and S glycoproteins on the infected cell surface using a microwell immunoperoxidase test. These two viral glycoproteins were easily detected on the plasma membrane of 0.1 % paraformaldehyde-fixed swine testis (ST) or pig kidney (RP.D) cells which were infected with high-passaged Purdue-115 and low-passaged D-52 strains and a high-passaged attenuated (188-SG) mutant of TGEV. No significant differences were found between attenuated and virulent strains with regard to the viral antigen expression on the membrane of infected cells over a 14-h period.

• Publication year

  2007

• Venue

  Research in Virology

• Publication date

  2007-09-22

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0923-2516(06)80112-3PMID 1329166PMCID 7135706
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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