Highly lymphatic metastatic pancreatic cancer cells possess stem cell-like properties.

No abstract is available for this paper.

• Publication year

  2013

• Venue

  International Journal of Oncology

• Publication date

  2013-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.3892/ijo.2013.1780PMID 23338123
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Pancreatic cancer stem cells: emerging target for designing novel therapy.

  2013cited by this paper
• MicroRNAs and cancer stem cells: therapeutic approaches and future perspectives.

  2013cited by this paper
• Development of a unique mouse model for pancreatic cancer lymphatic metastasis.

  2012influential reference
• SDF-1/CXCR4 signaling induces pancreatic cancer cell invasion and epithelial-mesenchymal transition in vitro through non-canonical activation of Hedgehog pathway.

  2012cited by this paper
• [Pancreatic carcinoma].

  2012cited by this paper
• Pancreatic cancer tumour initiating cells: the molecular regulation and therapeutic values

  2012cited by this paper
• microRNA signature for human pancreatic cancer invasion and metastasis.

  2012cited by this paper
• Stroma and pancreatic ductal adenocarcinoma: an interaction loop.

  2012cited by this paper
• Imaging-guided curative surgical resection of pancreatic cancer in a xenograft mouse model.

  2012cited by this paper
• MicroRNA regulation of cancer stem cells.

  2011cited by this paper
• LyP-1-conjugated nanoparticles for targeting drug delivery to lymphatic metastatic tumors.

  2010cited by this paper
• Epigenetic regulation of miR-184 by MBD1 governs neural stem cell proliferation and differentiation.

  2010cited by this paper
• Identification of miR-34a as a potent inhibitor of prostate cancer progenitor cells and metastasis by directly repressing CD44

  2010cited by this paper
• Enhanced cell migration and invasion of CD133+ pancreatic cancer cells cocultured with pancreatic stromal cells

  2010cited by this paper
• Identification of liver metastasis-related genes in a novel human pancreatic carcinoma cell model by microarray analysis.

  2009cited by this paper
• Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway.

  2009cited by this paper
• MicroRNA miR-34 Inhibits Human Pancreatic Cancer Tumor-Initiating Cells

  2009cited by this paper
• CD44‐positive cells are responsible for gemcitabine resistance in pancreatic cancer cells

  2009cited by this paper
• RNA interference of MBD1 in BxPC-3 human pancreatic cancer cells delivered by PLGA-poloxamer nanoparticles

  2009cited by this paper
• The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

  2009cited by this paper
• Cancer Statistics, 2009

  2009cited by this paper
• Circulating microRNAs as stable blood-based markers for cancer detection

  2008cited by this paper
• Proteomic analysis of differential proteins in pancreatic carcinomas: Effects of MBD1 knock-down by stable RNA interference

  2008cited by this paper
• Cancer stem cells in solid tumours: accumulating evidence and unresolved questions

  2008cited by this paper
• Development and Characterization of Gemcitabine-Resistant Pancreatic Tumor Cells

  2007cited by this paper
• let-7 regulates self renewal and tumorigenicity of breast cancer cells.

  2007influential reference
• Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer.

  2007influential reference
• A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

  2007cited by this paper
• Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells.

  2006cited by this paper
• EXPRESSION OF UBIQUITIN-SPECIFIC PROTEASE 14 IN HUMAN PANCREATIC CANCER CELL LINES AND CANCER TISSUES

  2005cited by this paper
• Stem cell division is regulated by the microRNA pathway

  2005cited by this paper
• Identification of human brain tumour initiating cells

  2004cited by this paper
• Identification of a cancer stem cell in human brain tumors.

  2003cited by this paper
• Regulation of microtubule stability and mitotic progression by survivin.

  2002cited by this paper
• Standard versus extended lymphadenectomy associated with pancreatoduodenectomy in the surgical treatment of adenocarcinoma of the head of the pancreas: a multicenter, prospective, randomized study. Lymphadenectomy Study Group.

  1998cited by this paper
• Pancreatic carcinoma.

  1992cited by this paper

• Tumor immune evasion and the Let-7 family: insights into mechanisms and therapies

  2025cites this paper
• Rosuvastatin Enhances Lymphangiogenesis after Myocardial Infarction by Regulating the miRNAs/Vascular Endothelial Growth Factor Receptor 3 (miRNAs/VEGFR3) Pathway.

  2024cites this paper
• Evaluation of Clinically Significant miRNAs Level by Machine Learning Approaches Utilizing Total Transcriptome Data

  2024cites this paper
• Lin28 Regulates Cancer Cell Stemness for Tumour Progression

  2022cites this paper
• The Roles of the Let-7 Family of MicroRNAs in the Regulation of Cancer Stemness

  2021cites this paper
• Regulation of Pancreatic Fibrosis by Acinar Cell-Derived Exosomal miR-130a-3p via Targeting of Stellate Cell PPAR-γ

  2020cites this paper
• LncRNA TP73-AS1 sponges miR-141-3p to promote the migration and invasion of pancreatic cancer cells through the up-regulation of BDH2

  2019cites this paper
• Epigenetics: Dissecting Gene Expression Alteration in PDAC

  2018cites this paper
• Pleiotropic functions of miR107 in cancer networks

  2018influential citation
• Chapter 3 miRNAs in Pancreatic Cancer

  2017cites this paper
• microRNA regulation of human pancreatic cancer stem cells.

  2017influential citation
• Emerging roles of the CXCL12/CXCR4 axis in pancreatic cancer progression and therapy☆

  2017cites this paper
• Pancreatic Cancer Stem Cells and Therapeutic Approaches.

  2017cites this paper
• miR-141-3p Suppresses Expression of Androgen Receptors and Functions as a Tumor Suppressor Gene in Prostate Carcinogenesis

  2017cites this paper
• Metastatic Pancreatic Cancer

  2017cites this paper
• Chapter 2 Stem Cells in Pancreatic Cancer

  2017cites this paper
• Human thymic stromal lymphopoietin promotes the proliferation and invasion of cervical cancer cells by downregulating microRNA-132 expression.

  2017cites this paper
• MiR‐107 down‐regulates SIAH1 expression in human breast cancer cells and silencing of miR‐107 inhibits tumor growth in a nude mouse model of triple‐negative breast cancer

  2016cites this paper
• Suppressing H19 Modulates Tumorigenicity and Stemness in U251 and U87MG Glioma Cells

  2016cites this paper
• Downregulation of microRNA-132 indicates progression in hepatocellular carcinoma

  2016cites this paper
• The ever-changing landscape of pancreatic cancer stem cells.

  2016cites this paper
• miR-128 regulates differentiation of hair follicle mesenchymal stem cells into smooth muscle cells by targeting SMAD2.

  2016cites this paper
• Targeting cancer stem cells and signaling pathways by phytochemicals: Novel approach for breast cancer therapy.

  2016cites this paper
• eview argeting cancer stem cells and signaling pathways by hytochemicals : Novel approach for breast cancer therapy

  2016cites this paper
• Principles of Stem Cell Biology and Cancer: Future Applications and Therapeutics

  2015cites this paper
• Recent advances in pancreatic cancer: biology, treatment, and prevention.

  2015cites this paper
• Antisense inhibition of microRNA-21 and microRNA-221 in tumor-initiating stem-like cells modulates tumorigenesis, metastasis, and chemotherapy resistance in pancreatic cancer

  2015cites this paper
• Concise Review: Custodians of the Transcriptome: How MicroRNAs Guard Stemness in Squamous Epithelia

  2015cites this paper
• Standardizing Variant Interpretation in Genomic Sequencing: Implications for Genetic Counseling Practice

  2015cites this paper
• Lymph node status predicts the benefit of adjuvant chemoradiotherapy for patients with resected pancreatic cancer.

  2015cites this paper
• GSK3β mediates pancreatic cancer cell invasion in vitro via the CXCR4/MMP-2 Pathway

  2015cites this paper
• Prostate cancer and prostate cancer stem cells

  2015cites this paper
• Clinical implications of miRNAs in the pathogenesis, diagnosis and therapy of pancreatic cancer.

  2015cites this paper
• Effect of the number of positive lymph nodes and lymph node ratio on prognosis of patients after resection of pancreatic adenocarcinoma.

  2014cites this paper
• Cancer stem cells: involvement in pancreatic cancer pathogenesis and perspectives on cancer therapeutics.

  2014cites this paper
• MicroRNAs in cancer stem cells: new regulators of stemness.

  2014cites this paper
• MicroRNA modulation in combination with chemotherapeutic drugs as a novel therapeutic strategy for pancreatic cancer

  2014cites this paper
• miRNAs in Pancreatic Cancer

  2014cites this paper
• H19 promotes pancreatic cancer metastasis by derepressing let-7’s suppression on its target HMGA2-mediated EMT

  2014cites this paper
• TOPIC HIGHLIGHT

  2014cites this paper
• Stem Cells in Pancreatic Cancer

  2014cites this paper
• Identification and comparative analysis of the Pseudosciaena crocea microRNA transcriptome response to poly(I:C) infection using a deep sequencing approach.

  2014cites this paper
• Transient Activation of Hedgehog Pathway Rescued Irradiation-Induced Hyposalivation by Preserving Salivary Stem/Progenitor Cells and Parasympathetic Innervation

  2013cites this paper
• Functional role of miR-34 family in human cancer.

  2013cites this paper
• miR-139 targets CXCR4 and inhibits the proliferation and metastasis of laryngeal squamous carcinoma cells

  2013cites this paper
• Functional role of solid tumor stem cells in disease etiology and susceptibility to therapeutic interventions.

  2013cites this paper