New Insights into the Not-So-New NR 3 Subunits of N-Methyl-D-aspartate Receptor : Localization , Structure , and Function

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Unknown venue

• Publication date

  Unknown publication date

• Fields of study

  Not labeled

• Identifiers

  No identifiers available.

• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Circadian and developmental regulation of N-methyl-d-aspartate-receptor 1 mRNA splice variants and N-methyl-d-aspartate-receptor 3 subunit expression within the rat suprachiasmatic nucleus.

  2009cited by this paper
• Downregulation of NR3A-containing NMDARs is required for synapse maturation and memory consolidation.

  2009influential reference
• X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor

  2009cited by this paper
• The amino terminal domain of GluR6 subtype glutamate receptor ion channels

  2009cited by this paper
• Crystal structure and association behaviour of the GluR2 amino‐terminal domain

  2009cited by this paper
• Structure of the zinc‐bound amino‐terminal domain of the NMDA receptor NR2B subunit

  2009cited by this paper
• Neuroprotection by the NR3A Subunit of the NMDA Receptor

  2009cited by this paper
• Supralinear potentiation of NR1/NR3A excitatory glycine receptors by Zn2+ and NR1 antagonist

  2008cited by this paper
• Modulation of NMDA receptor properties and synaptic transmission by the NR3A subunit in mouse hippocampal and cerebrocortical neurons.

  2008influential reference
• Structural insights into phenylethanolamines high-affinity binding site in NR2B from binding and molecular modeling studies

  2008cited by this paper
• Molecular mechanism of ligand recognition by NR3 subtype glutamate receptors

  2008influential reference
• Binding of spermine and ifenprodil to a purified, soluble regulatory domain of the N‐methyl‐d‐aspartate receptor

  2008cited by this paper
• Rules of engagement for NMDA receptor subunits

  2008cited by this paper
• Shuffling the Deck Anew: How NR3 Tweaks NMDA Receptor Function

  2008cited by this paper
• Formation of NR1/NR2 and NR1/NR3 Heterodimers Constitutes the Initial Step in N-Methyl-D-aspartate Receptor Assembly*

  2008cited by this paper
• Expression of the N-methyl-D-aspartate receptor subunit NR3B regulates dendrite morphogenesis in spinal motor neurons.

  2008cited by this paper
• Immunolocalization of NMDA receptor subunit NR3B in selected structures in the rat forebrain, cerebellum, and lumbar spinal cord

  2008cited by this paper
• Genetic ablation of NMDA receptor subunit NR3B in mouse reveals motoneuronal and nonmotoneuronal phenotypes

  2007influential reference
• Principal role of NR3 subunits in NR1/NR3 excitatory glycine receptor function.

  2007influential reference
• Improving solubility of NR2B amino-terminal domain of N-methyl-d-aspartate receptor expressed in Escherichia coli.

  2007cited by this paper
• Pharmacological Characterization of Glycine-Activated Currents in HEK 293 Cells Expressing N-Methyl-D-aspartate NR1 and NR3 Subunits

  2007influential reference
• Subunit-Specific Roles of Glycine-Binding Domains in Activation of NR1/NR3 N-Methyl-d-aspartate Receptors

  2007influential reference
• NR3A Modulates the Outer Vestibule of the “NMDA” Receptor Channel

  2006influential reference
• Characterization of a Soluble Ligand Binding Domain of the NMDA Receptor Regulatory Subunit NR3A

  2006influential reference
• Endocytosis and synaptic removal of NR3A-containing NMDA receptors by PACSIN1/syndapin1

  2006cited by this paper
• Subunit arrangement and function in NMDA receptors

  2005cited by this paper
• Mechanism of partial agonist action at the NR1 subunit of NMDA receptors.

  2005cited by this paper
• NMDA receptors are expressed in oligodendrocytes and activated in ischaemia

  2005cited by this paper
• NR2 to NR3B subunit switchover of NMDA receptors in early postnatal motoneurons

  2005cited by this paper
• The NR3B Subunit Does Not Alter the Anesthetic Sensitivities of Recombinant N-Methyl-d-Aspartate Receptors

  2005influential reference
• Cloning and expression of the human NMDA receptor subunit NR3B in the adult human hippocampus.

  2005cited by this paper
• Expression and characterization of soluble amino‐terminal domain of NR2B subunit of N‐methyl‐d‐aspartate receptor

  2005cited by this paper
• Alterations in ionotropic glutamate receptor subunits during binge cocaine self‐administration and withdrawal in rats

  2004cited by this paper
• Switching of NMDA Receptor 2A and 2B Subunits at Thalamic and Cortical Synapses during Early Postnatal Development

  2004cited by this paper
• Lateral organization of endocytic machinery in dendritic spines

  2004cited by this paper
• Structure and function of glutamate receptor ion channels.

  2004cited by this paper
• Receptor compartmentalization and trafficking at glutamate synapses: a developmental proposal.

  2004cited by this paper
• Specific Assembly with the NMDA Receptor 3B Subunit Controls Surface Expression and Calcium Permeability of NMDA Receptors

  2003influential reference
• Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes

  2003cited by this paper
• Structural basis for partial agonist action at ionotropic glutamate receptors

  2003cited by this paper
• Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand‐binding core

  2003influential reference
• Mapping the Binding Site of the Neuroprotectant Ifenprodil on NMDA Receptors

  2002cited by this paper
• Characterization and comparison of the NR3A subunit of the NMDA receptor in recombinant systems and primary cortical neurons.

  2002cited by this paper
• Cloning and characterization of a novel NMDA receptor subunit NR3B: a dominant subunit that reduces calcium permeability.

  2002influential reference
• Association of NR3A with the N-methyl-D-aspartate receptor NR1 and NR2 subunits.

  2002cited by this paper
• Excitatory glycine receptors containing the NR3 family of NMDA receptor subunits

  2002influential reference
• Cloning and expression of the human N-methyl-D-aspartate receptor subunit NR3A.

  2002cited by this paper
• Dynamics and regulation of clathrin coats at specialized endocytic zones of dendrites and spines.

  2002cited by this paper
• Temporal and regional expression of NMDA receptor subunit NR3A in the mammalian brain

  2002influential reference
• Structural basis for AMPA receptor activation and ligand selectivity: crystal structures of five agonist complexes with the GluR2 ligand-binding core.

  2002cited by this paper
• Assembly with the NR1 Subunit Is Required for Surface Expression of NR3A-Containing NMDA Receptors

  2001cited by this paper
• Motoneuron-Specific Expression of NR3B, a Novel NMDA-Type Glutamate Receptor Subunit That Works in a Dominant-Negative Manner

  2001influential reference
• NMDAR EPSC kinetics do not regulate the critical period for LTP at thalamocortical synapses

  2001influential reference
• Mechanisms for ligand binding to GluR0 ion channels: crystal structures of the glutamate and serine complexes and a closed apo state.

  2001cited by this paper
• Nucleotide sequence, genomic organization, and chromosomal localization of genes encoding the human NMDA receptor subunits NR3A and NR3B.

  2001influential reference
• Do NMDA receptor kinetics regulate the end of critical periods of plasticity?

  2001cited by this paper
• Single-cell RT-PCR analysis of N-methyl-D-aspartate receptor subunit expression in rat locus coeruleus neurones

  2000cited by this paper
• Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core.

  2000cited by this paper
• NMDA receptor subunit gene expression in the rat brain: a quantitative analysis of endogenous mRNA levels of NR1Com, NR2A, NR2B, NR2C, NR2D and NR3A.

  1999cited by this paper
• Central nervous system neuronal migration.

  1999cited by this paper
• Expression of NMDA glutamate receptor subunit mRNAs in neurochemically identified projection and interneurons in the striatum of the rat.

  1999cited by this paper
• The glutamate receptor ion channels.

  1999influential reference
• Early postnatal switch in magnesium sensitivity of NMDA receptors in rat CA1 pyramidal cells

  1999cited by this paper
• Structure of a glutamate-receptor ligand-binding core in complex with kainate

  1998cited by this paper
• Increased NMDA current and spine density in mice lacking the NMDA receptor subunit NR3A

  1998cited by this paper
• Identification of a long variant of mRNA encoding the NR3 subunit of the NMDA receptor: its regional distribution and developmental expression in the rat brain

  1998cited by this paper
• Internal Mg2+ block of recombinant NMDA channels mutated within the selectivity filter and expressed in Xenopus oocytes

  1998cited by this paper
• Overexpression of a glutamate receptor (GluR2) ligand binding domain in Escherichia coli: application of a novel protein folding screen.

  1997cited by this paper
• Regional, developmental and interspecies expression of the four NMDAR2 subunits, examined using monoclonal antibodies.

  1997influential reference
• Expression of NMDAR2D glutamate receptor subunit mRNA in neurochemically identified interneurons in the rat neostriatum, neocortex and hippocampus.

  1996cited by this paper
• Activation of N-methyl-D-aspartate receptors by glycine: role of an aspartate residue in the M3-M4 loop of the NR1 subunit.

  1996cited by this paper
• Ontogeny of NMDA R1 subunit protein expression in five regions of rat brain.

  1996cited by this paper
• Regional and Ontogenic Expression of the NMDA Receptor Subunit NR2D Protein in Rat Brain Using a Subunit‐Specific Antibody

  1996cited by this paper
• Cloning and characterization of chi-1: a developmentally regulated member of a novel class of the ionotropic glutamate receptor family

  1995influential reference
• D-serine, an endogenous synaptic modulator: localization to astrocytes and glutamate-stimulated release.

  1995cited by this paper
• Structure and function of the NMDA receptor channel.

  1995cited by this paper
• Developmental and regional expression pattern of a novel NMDA receptor- like subunit (NMDAR-L) in the rodent brain

  1995influential reference
• Developmental and regional expression in the rat brain and functional properties of four NMDA receptors.

  1994cited by this paper
• Regulation of NMDA receptor subunit mRNA expression in the rat brain during postnatal development.

  1994cited by this paper
• The NMDA receptor subunits NR2A and NR2B show histological and ultrastructural localization patterns similar to those of NR1

  1994cited by this paper
• Light and electron microscope distribution of the NMDA receptor subunit NMDAR1 in the rat nervous system using a selective anti-peptide antibody

  1994cited by this paper
• NMDA-receptor channel diversity in the developing cerebellum

  1994cited by this paper
• Cloned glutamate receptors.

  1994cited by this paper
• Expression of the gene coding for the NR1 subunit of the NMDA receptor during rat brain development.

  1993cited by this paper
• Developmental switch in the expression of NMDA receptors occurs in vivo and in vitro.

  1993cited by this paper
• The glycine site of the NMDA receptor--five years on.

  1993cited by this paper
• Subtypes of NMDA receptors.

  1993cited by this paper
• Heteromeric NMDA Receptors: Molecular and Functional Distinction of Subtypes

  1992cited by this paper
• Functional localization and lateralization of human olfactory cortex

  1992cited by this paper
• Glycine is required for NMDA receptor activation: electrophysiological evidence from intact rat hippocampus.

  1992cited by this paper
• Molecular cloning and characterization of the rat NMDA receptor

  1991cited by this paper
• Requirement for glycine in activation of NMDA-receptors expressed in Xenopus oocytes.

  1988cited by this paper
• Glycine potentiates the NMDA response in cultured mouse brain neurons

  1987cited by this paper
• Magnesium gates glutamate-activated channels in mouse central neurones

  1984cited by this paper
• Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neurones

  1984cited by this paper
• Inhibition of spinal neurons by glycine.

  1967cited by this paper

• Maternal High-Fat diet During Pregnancy and Lactation Disrupts NMDA Receptor Expression and Spatial Memory in the Offspring

  2022cites this paper
• Cerebellar developmental deficits underlie neurodegenerative disorder spinocerebellar ataxia type 23

  2020cites this paper
• The Role of NMDA Receptors in Alzheimer’s Disease

  2019cites this paper
• The molecular neuropathology of spinocerebellar ataxia type 23 Smeets

  2018cites this paper
• GRIN3B missense mutation as an inherited risk factor for schizophrenia: whole-exome sequencing in a family with a familiar history of psychotic disorders

  2017cites this paper
• Functional Properties of Human Stem Cell-Derived Neurons in Health and Disease

  2016cites this paper
• Emerging roles of GluN3-containing NMDA receptors in the CNS

  2016cites this paper
• The molecular neuropathology of spinocerebellar ataxia type 23

  2016cites this paper
• The molecular neuropathology of spinocerebellar ataxia type 23

  2016cites this paper
• Development of PET and SPECT Probes for Glutamate Receptors

  2015cites this paper
• Evidence for glycinergic GluN1/GluN3 NMDA receptors in hippocampal metaplasticity.

  2015cites this paper
• Oscillations dans la bande de fréquence gamma dans des modèles de rongeurs pour la schizophrénie

  2014cites this paper
• NMDA and AMPA receptors: development and status epilepticus.

  2013cites this paper
• Cortical activation of accumbens hyperpolarization-active NMDARs mediates aversion-resistant alcohol intake

  2013cites this paper
• GluN3A: An NMDA Receptor Subunit with Exquisite Properties and Functions

  2013cites this paper
• Intrinsically photosensitive retinal ganglion cells are resistant to N-methyl-D-aspartic acid excitotoxicity

  2012cites this paper
• Identification of four functional NR3B isoforms in developing white matter reveals unexpected diversity among glutamate receptors

  2011cites this paper
• Selective inhibition of GluN2D-containing N-methyl-D-aspartate receptors prevents tissue plasminogen activator-promoted neurotoxicity both in vitro and in vivo

  2011cites this paper