IGF and IGF-binding protein system in the synovial fluid of osteoarthritic and rheumatoid arthritic patients.

No abstract is available for this paper.

• Publication year

  1996

• Venue

  Osteoarthritis and Cartilage

• Publication date

  1996-12-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/S1063-4584(05)80104-9PMID 11048623
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Normal expression of type 1 insulin-like growth factor receptor by human osteoarthritic chondrocytes with increased expression and synthesis of insulin-like growth factor binding proteins.

  1996cited by this paper
• Detection of insulin-like growth factor I and II in synovial tissue specimens of patients with rheumatoid arthritis and osteoarthritis by in situ hybridization.

  1995cited by this paper
• RS3PE syndrome associated with advanced ankylosing spondylitis.

  1995cited by this paper
• Increased insulin-like growth factor 1 production by human osteoarthritic chondrocytes is not dependent on growth hormone action.

  1995cited by this paper
• Proteolytic degradation of insulin-like growth factor (IGF)-binding protein-3 by porcine ovarian granulosa cells in culture: regulation by IGF-I.

  1994cited by this paper
• Serum levels of insulin-like growth factor in subjects with osteoarthritis of the knee. Data from the Baltimore Longitudinal Study of Aging.

  1994cited by this paper
• Regulation of immunoreactive insulin-like growth factor binding protein-6 in normal and transformed human fibroblasts.

  1994cited by this paper
• Effects of interleukin-1 beta on insulin-like growth factor-I autocrine/paracrine axis in cultured rat articular chondrocytes.

  1994cited by this paper
• Evidence that human bone cells in culture produce insulin-like growth factor-binding protein-4 and -5 proteases.

  1994cited by this paper
• Human osteoarthritic chondrocytes possess an increased number of insulin-like growth factor 1 binding sites but are unresponsive to its stimulation. Possible role of IGF-1-binding proteins.

  1994cited by this paper
• Acid-activated insulin-like growth factor-binding protein-3 proteolysis in normal and transformed cells. Role of cathepsin D.

  1994cited by this paper
• Matrix metalloproteinases degrade insulin-like growth factor-binding protein-3 in dermal fibroblast cultures.

  1994cited by this paper
• Human fibroblasts secrete a serine protease that cleaves insulin-like growth factor-binding protein-5.

  1994cited by this paper
• Glucocorticoid regulation of insulin-like growth factor-binding protein expression in normal human osteoblast-like cells.

  1994cited by this paper
• Regulation of insulin‐like growth factor binding protein 4 by a specific insulin‐like growth factor binding protein 4 proteinase in normal human osteoblast‐like cells: Implications in bone cell physiology

  1994cited by this paper
• IGF binding proteins and their functions

  1993cited by this paper
• Metalloproteinases, tissue inhibitor, and proteoglycan fragments in knee synovial fluid in human osteoarthritis.

  1993cited by this paper
• Insulin-like growth factor (IGF) binding proteins and insulin-like growth factor secretion by cultured chondrocyte cells: identification, characterization and ontogeny during cell differentiation.

  1993cited by this paper
• Insulin‐like growth factor‐l blood levels in severely burned patients: effects of time post injury, age of patient and severity of burn

  1993cited by this paper
• Levels of insulin related growth factor 1 in osteoarthritis of the knee.

  1993cited by this paper
• Production and hormonal regulation of insulin-like growth factor binding proteins in bovine chondrocytes.

  1993cited by this paper
• Generalized osteoarthritis associated with increased insulin-like growth factor types I and II and transforming growth factor beta in cortical bone from the iliac crest. Possible mechanism of increased bone density and protection against osteoporosis.

  1993cited by this paper
• Cytokines modulate the sensitivity of human fibroblasts to stimulation with insulin-like growth factor-I (IGF-I) by altering endogenous IGF-binding protein production.

  1993cited by this paper
• Measurement and characterization of insulin-like growth factor binding protein-3 in human biological fluids: discrepancies between radioimmunoassay and ligand blotting.

  1992cited by this paper
• Detection of stromelysin and collagenase in synovial fluid from patients with rheumatoid arthritis and posttraumatic knee injury.

  1992cited by this paper
• Upregulation of insulin-like growth factor I gene expression in the lesions of osteoarthritic human articular cartilage.

  1992cited by this paper
• Basal and regulated secretion of insulin-like growth factor binding proteins in osteoblast-like cells is cell line specific.

  1992cited by this paper
• Identification of the forms of insulin-like growth factor-binding proteins produced by human fibroblasts and the mechanisms that regulate their secretion.

  1992cited by this paper
• Involvement of the plasmin system in dissociation of the insulin-like growth factor-binding protein complex.

  1992cited by this paper
• Are cytokines involved in osteoarthritic pathophysiology?

  1991cited by this paper
• Measurement of insulin-like growth factor-II in physiological fluids and tissues. I. An improved extraction procedure and radioimmunoassay for human and rat fluids.

  1991cited by this paper
• Differential effects of insulin-like growth factors I and II on growth, differentiation and glucoregulation in differentiating chondrocyte cells in culture.

  1991cited by this paper
• A novel human insulin-like growth factor binding protein secreted by osteoblast-like cells.

  1991cited by this paper
• Growth promoting peptides in osteoarthritis: insulin, insulin-like growth factor-1, growth hormone.

  1991cited by this paper
• A simple assay for proteolysis of IGFBP-3.

  1991cited by this paper
• Synovial membrane histology and immunopathology in rheumatoid arthritis and osteoarthritis. In vivo effects of antirheumatic drugs.

  1991cited by this paper
• Isolation of a novel insulin-like growth factor (IGF) binding protein from human bone: a potential candidate for fixing IGF-II in human bone.

  1991cited by this paper
• Growth promoting peptides in osteoarthritis: insulin, insulin-like growth factor-1, growth hormone.

  1990cited by this paper
• Evidence of enzymatic degradation of insulin-like growth factor-binding proteins in the 150K complex during pregnancy.

  1990cited by this paper
• In vitro insulin-like growth factor I interaction with cartilage cells derived from postnatal animals.

  1990cited by this paper
• Insulin-like growth factor binding proteins in maternal serum throughout gestation and in the puerperium: effects of a pregnancy-associated serum protease activity.

  1990cited by this paper
• Insulin-like growth factor-I concentration in Holstein female cattle: variations with age, stage of lactation and growth hormone-releasing factor administration.

  1990cited by this paper
• Insulin-like growth factor 1 can decrease degradation and promote synthesis of proteoglycan in cartilage exposed to cytokines.

  1989cited by this paper
• CHONDROCYTE NONRESPONSIVENESS TO INSULIN‐LIKE GROWTH FACTOR 1 IN EXPERIMENTAL ARTHRITIS

  1989cited by this paper
• Production of insulin-like growth factors and their binding proteins by rabbit articular chondrocytes: relationships with cell multiplication.

  1989cited by this paper
• Insulin-like growth factor stimulation of chondrocyte proteoglycan synthesis by human synovial fluid.

  1989cited by this paper
• The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis.

  1988cited by this paper
• Cytokines in synovial fluid. I. The presence of biologically active and immunoreactive IL-1.

  1988cited by this paper
• Stimulation of proteoglycan biosynthesis by serum and insulin-like growth factor-I in cultured bovine articular cartilage.

  1986cited by this paper
• Analysis of serum insulin-like growth factor binding proteins using western blotting: use of the method for titration of the binding proteins and competitive binding studies.

  1986cited by this paper
• Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association.

  1986cited by this paper
• Radioimmunological determination of insulinlike growth factors I and II in normal subjects and in patients with growth disorders and extrapancreatic tumor hypoglycemia.

  1981cited by this paper
• Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

  1979cited by this paper
• Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

  1970cited by this paper

• IGFBP4 is a Metric for Primary Biliary Cholangitis and Attenuates Biliary Epithelial Cell Injury

  2026cites this paper
• IGFBP-6 as a potential therapeutic target in musculoskeletal disorders.

  2026cites this paper
• A systematic review of mesenchymal stem cell secretome: Functional annotations, gene clusters and proteomics analyses for bone formation.

  2024cites this paper
• Plasma Proteomic Analysis Based on 4D-DIA Evaluates the Clinical Response to Imrecoxib in the Early Treatment of Osteoarthritis

  2024cites this paper
• TNFα has differential effects on the transcriptome profile of selected populations in murine cartilage

  2024cites this paper
• Cross-species transcriptomics identifies obesity associated genes between human and mouse studies

  2024cites this paper
• Identification of Potential HUB Genes and Associated Transcription Factors in Rheumatoid Arthritis

  2023cites this paper
• Cross-sectional study of plasma Axl, ferritin, IGFBP4 and sTNFR2 as biomarkers of disease activity in childhood-onset SLE: A study of the Pediatric Nephrology Research Consortium

  2021cites this paper
• Effect of hypoxia/reoxygenation on the biological effect of IGF system and the inflammatory mediators in cultured synoviocytes.

  2019cites this paper
• Gene Expression Analysis of Chondrogenic Markers in Hair Follicle Dermal Papillae Cells Under the Effect of Laser Photobiomodulation and the Synovial Fluid.

  2019cites this paper
• IGFs and IGF-Binding Proteins in the Synovial Fluid of Patients with Rheumatoid Arthritis and Osteoarthritis

  2019cites this paper
• Insulin-Like Growth Factor Binding Proteins in Autoimmune Diseases

  2018cites this paper
• Onset and Progression of Human Osteoarthritis—Can Growth Factors, Inflammatory Cytokines, or Differential miRNA Expression Concomitantly Induce Proliferation, ECM Degradation, and Inflammation in Articular Cartilage?

  2018cites this paper
• Insulin-Like Growth Factor Binding Protein 6 in Rheumatoid Arthritis: A Possible Novel Chemotactic Factor?

  2017cites this paper
• Correlation of insulin-like growth factor 1 and osteoarthritic cartilage degradation: a spontaneous osteoarthritis in guinea-pig.

  2017cites this paper
• Polyphenol-Related Epigenetic Modifications in Osteoarthritis: Current Therapeutic Perspectives.

  2017cites this paper
• Systemic immune markers characterizing early stages of rheumatoid arthritis

  2016cites this paper
• Altération du phénotype chondrocytaire : Rôle de l’homéostasie locale de facteurs modulant la balance Pi/Ppi

  2016cites this paper
• Profiling drugs for rheumatoid arthritis that inhibit synovial fibroblast activation

  2016cites this paper
• A computational model for investigating the effects of changes in bioavailability of insulin-like growth factor-1 on the homeostasis of the intervertebral disc

  2016cites this paper
• IGFBP-3 may trigger osteoarthritis by inducing apoptosis of chondrocytes through Nur77 translocation.

  2015cites this paper
• Rheumatoid Arthritis, Immunosenescence and the Hallmarks of Aging

  2015cites this paper
• The ECM-Cell Interaction of Cartilage Extracellular Matrix on Chondrocytes

  2014cites this paper
• Regulation of chondrogenesis by protein kinase C: Emerging new roles in calcium signalling.

  2014cites this paper
• Modeling the role of IGF-1 on extracellular matrix biosynthesis and cellularity in intervertebral disc.

  2014cites this paper
• Cell/Tissue Microenvironment Engineering and Monitoring in Tissue Engineering, Regenerative Medicine, and In Vitro Tissue Models

  2014cites this paper
• Integrative studies on cartilage tissue engineering and joint homeostasis

  2014cites this paper
• Modeling the Insulin-Like Growth Factor System in Articular Cartilage

  2013cites this paper
• Generation of Scaffold Free 3-D Cartilage-Like Microtissues from Human Chondrocytes

  2013cites this paper
• Overview of cartilage biology and new trends in cartilage stimulation.

  2013cites this paper
• Functional relationship between high mobility group A1 (HMGA1) protein and insulin-like growth factor-binding protein 3 (IGFBP-3) in human chondrocytes

  2012cites this paper
• Reconstruct large osteochondral defects of the knee with hIGF-1 gene enhanced Mosaicplasty.

  2012cites this paper
• Regulatory Functions of Insulin-like Growth Factor Binding Proteins in Osteoarthritis

  2011cites this paper
• Beneficial Effects of Marine Bioactive Substances on Bone Health, via Osteoarthritis Inhibition and Osteoblast Differentiation

  2011cites this paper
• The transport of Insulin-Like growth factor through cartilage

  2010cites this paper
• Bioreactor Systems for Tissue Engineering II

  2010cites this paper
• Strategies for the expansion and directed differentiation of stem cells

  2010cites this paper
• IGFBP-5 Metabolism Is Disrupted in the Rat Medial Meniscal Tear Model of Osteoarthritis

  2010cites this paper
• REVIEW

  2010cites this paper
• Cartilage engineering from mesenchymal stem cells.

  2010cites this paper
• Complement 1s is the serine protease that cleaves IGFBP-5 in human osteoarthritic joint fluid.

  2009cites this paper
• Joint injury and osteoarthritis: soluble mediators in the course and treatment of cartilage pathology.

  2009cites this paper
• Enhanced Meniscal Repair by Overexpression of hIGF-1 in a Full-thickness Model

  2009cites this paper
• Cartilage in normal and osteoarthritis conditions.

  2008cites this paper
• Future tools for early diagnosis and monitoring of musculoskeletal injury: biomarkers and CT.

  2008cites this paper
• Molecular network of cartilage homeostasis and osteoarthritis

  2008cites this paper
• The Potential of IGF-1 and TGFβ1 for Promoting “Adult” Articular Cartilage Repair: An In Vitro Study

  2008cites this paper
• Targeting Growth Factors in Arthritis: A Rational for Restoring the IGF-I Response in Chondrocytes

  2008cites this paper
• IGF uptake with competitive binding in articular cartilage

  2008cites this paper
• Gene Expression Profiling of Rheumatoid Arthritis Synovial Cells Treated with Antirheumatic Drugs

  2007cites this paper
• The effect of cyclic deformation and solute binding on solute transport in cartilage.

  2007cites this paper
• Expression of insulin‐like growth factor binding proteins in healing tendon lesions

  2006cites this paper
• Modulation of insulin-like growth factor 1 levels in human osteoarthritic subchondral bone osteoblasts.

  2006cites this paper
• Signaling through the small G‐protein Cdc42 is involved in insulin‐like growth factor‐I resistance in aging articular chondrocytes

  2006cites this paper
• La leptine est-elle le maillon manquant entre l'arthrose et l'obésité ?

  2005cites this paper
• Distribution of components of the insulin-like growth factor system in the temporomandibular joint of the aging mouse.

  2005cites this paper
• [Is leptin the missing link between osteoarthritis and obesity?].

  2005cites this paper
• Role of the growth hormone/insulin-like growth factor-1 paracrine axis in rheumatic diseases.

  2005cites this paper
• Effects of long-term estrogen replacement therapy on articular cartilage IGFBP-2, IGFBP-3, collagen and proteoglycan levels in ovariectomized cynomolgus monkeys.

  2004cites this paper
• Pharmacological disruption of insulin-like growth factor 1 binding to IGF-binding proteins restores anabolic responses in human osteoarthritic chondrocytes

  2004cites this paper
• Osteophyte development--molecular characterization of differentiation stages.

  2003cites this paper
• Signaling Mechanisms Leading to the Regulation of Differentiation and Apoptosis of Articular Chondrocytes by Insulin-like Growth Factor-1*

  2003cites this paper
• Changes in the local regulation of insulin-like growth factors I and II and insulin-like growth factor-binding proteins in osteoarthritis of the canine stifle joint secondary to cruciate ligament rupture.

  2003cites this paper
• One of two chondrocyte-expressed isoforms of cartilage intermediate-layer protein functions as an insulin-like growth factor 1 antagonist.

  2003cites this paper
• Articular Cartilage Biology

  2003cites this paper
• Novel strategies for enhancing tissue integration in cartilage repair

  2003cites this paper
• Review Neural immune pathways and their connection to inflammatory

  2003cites this paper
• Neural immune pathways and their connection to inflammatory diseases

  2003cites this paper
• Evidence for a key role of leptin in osteoarthritis.

  2003cites this paper
• Arthritis-induced increase in serum levels of IGF-binding protein-3 in rats is secondary to the decrease in its proteolytic activity.

  2002cites this paper
• Inhibition of insulin-like growth factor binding protein 5 proteolysis in articular cartilage and joint fluid results in enhanced concentrations of insulin-like growth factor 1 and is associated with improved osteoarthritis.

  2002cites this paper
• Fibronectin fragments upregulate insulin-like growth factor binding proteins in chondrocytes.

  2002cites this paper
• The Novartis-ILAR Rheumatology Prize 2001 Osteoarthritis: from molecule to man

  2001cites this paper
• Insulin‐like growth factor‐I gene expression patterns during spontaneous repair of acute articular cartilage injury

  2001cites this paper
• The Insulin-like Growth Factors (IGFs) I and II Bind to Articular Cartilage via the IGF-binding Proteins*

  2000cites this paper
• Alterations in insulin-like growth factor binding protein-3 proteolysis and complex formation in the arthritic joint.

  2000cites this paper
• The Insulin-Like Growth Factor (IGF) Binding Proteins (IGFBPS)

  1999cites this paper
• Metabolic disturbances and synovial joint responses in osteoarthritis.

  1999cites this paper
• IGF/IGFBP axis in cartilage and bone in osteoarthritis pathogenesis

  1998cites this paper
• The role and content of endogenous insulin-like growth factor-binding proteins in bovine articular cartilage.

  1997cites this paper
• Normal expression of type 1 insulin-like growth factor receptor by human osteoarthritic chondrocytes with increased expression and synthesis of insulin-like growth factor binding proteins.

  1996cites this paper