An epidemic of veno-occlusive disease of the liver in Afghanistan. Pathologic features.

No abstract is available for this paper.

• Publication year

  1978

• Venue

  American Journal of Gastroenterology

• Publication date

  Unknown publication date

• Fields of study

  Medicine

• Identifiers
  PMID 742612
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A pathological study of the liver in an epidemic outbreak of veno-occlusive disease.

  1977cited by this paper
• Study of an epidemic of venoocclusive disease in India.

  1976cited by this paper
• An outbreak of hepatic veno-occlusive disease in north-western Afghanistan.

  1976cited by this paper
• Hepatic veins of monkeys with veno-occlusive disease. Sequential ultrastructural changes.

  1969cited by this paper
• Portal hypertension in acute experimental veno-occlusive disease of the liver in rats.

  1969cited by this paper
• The early lesions in veno-occlusive disease of the liver.

  1962cited by this paper
• Cirrhosis of the liver in Jamaica.

  1961cited by this paper
• The world-wide distribution of seneciosis in man and animals.

  1960cited by this paper
• The chronic pathological effects on the liver of the rat of the pyrrolizidine alkaloids heliotrine, lasiocarpine, and their N-oxides.

  1959cited by this paper
• Veno-occlusive disease of liver with nonportal type of cirrhosis, occurring in Jamaica.

  1954cited by this paper
• Serous Hepatosis: A Pathogenesis of Hepatic Fibrosis in Jamaican Children

  1953cited by this paper
• Senecio poisoning exhibiting as Chiari's syndrome; a report on twelve cases.

  1951cited by this paper

• The pyrrolizidine alkaloid lasiocarpine impairs cell cycle progression in vitro

  2025cites this paper
• Metabolic Toxification of 1,2-Unsaturated Pyrrolizidine Alkaloids Causes Human Hepatic Sinusoidal Obstruction Syndrome: The Update

  2021cites this paper
• Pyrrolizidine Alkaloids Disturb Bile Acid Homeostasis in the Human Hepatoma Cell Line HepaRG

  2021cites this paper
• Heliotropium; a genus rich in pyrrolizidine alkaloids: A systematic review following its phytochemistry and pharmacology

  2021cites this paper
• Pyrrolizidine alkaloids - Tumorigenic components in Chinese herbal medicines and dietary supplements

  2020cites this paper
• Drug induced liver injury and vascular liver disease.

  2020cites this paper
• Investigation Of Pyrrolizidine Alkaloids In Foods Using Liquid Chromatography Mass Spectrometry

  2020cites this paper
• Novel strategies for risk assessment of pyrrolizidine alkaloids

  2019cites this paper
• Use of an in vitro–in silico testing strategy to predict inter-species and inter-ethnic human differences in liver toxicity of the pyrrolizidine alkaloids lasiocarpine and riddelliine

  2019cites this paper
• BIOLOGICAL AND PHARMACOLOGICAL STUDIES OF HELIOTROPIUM

  2019cites this paper
• Pyrrolizidine alkaloids act by toxicity to sinusoidal endothelial cells of the liver

  2019cites this paper
• The pyrrolizidine alkaloid senecionine induces CYP-dependent destruction of sinusoidal endothelial cells and cholestasis in mice

  2019cites this paper
• The History of the Glycosidase Inhibiting Hyacinthacine C-type Alkaloids: From Discovery to Synthesis

  2019cites this paper
• New glutathione conjugate of pyrrolizidine alkaloids produced by human cytosolic enzyme-dependent reactions in vitro.

  2018cites this paper
• CYTOTOXIC, α-CHYMOTRYPSIN AND UREASE INHIBITION ACTIVITIES OF THE PLANT Heliotropium dasycarpum L.

  2016cites this paper
• Ethnopharmacological, Phytochemical and Pharmacognostic Potential of Genus Heliotropıum L.

  2016cites this paper
• Species-Specific Differences in the in Vitro Metabolism of Lasiocarpine.

  2015cites this paper
• THE EFFECTS OF AQUEOUS LEAF EXTRACT OF SYMPHYTUM OFFICINALE (COMMON COMFREY) ON THE LIVER ENZYMES OF ADULT WISTAR RATS

  2015cites this paper
• Herbal hepatotoxicity in traditional and modern medicine: actual key issues and new encouraging steps

  2015cites this paper
• In silico prediction of the site of oxidation by cytochrome P450 3A4 that leads to the formation of the toxic metabolites of pyrrolizidine alkaloids.

  2015cites this paper
• Safety concerns of herbal products and traditional Chinese herbal medicines: dehydropyrrolizidine alkaloids and aristolochic acid

  2015cites this paper
• Identification of a new reactive metabolite of pyrrolizidine alkaloid retrorsine: (3H-pyrrolizin-7-yl)methanol.

  2014cites this paper
• Hepatotoxicity of Botanicals

  2014cites this paper
• ANTIMICROBIAL AND PHYTOTOXIC EFFECTS OF THE PLANT HELIOTROPIUM DASYCARPUM L.

  2013cites this paper
• Aetiology of an unknown liver disease in northern Ethiopia

  2012cites this paper
• Diagnostisches Vorgehen bei Lebererkrankungen durch pflanzliche Mittel

  2012cites this paper
• Herbal hepatotoxicity: a tabular compilation of reported cases

  2012cites this paper
• ¹H NMR study of monocrotaline and its metabolites in human blood.

  2011cites this paper
• Pyrrolizidine alkaloid toxicity in livestock: a paradigm for human poisoning?

  2011influential citation
• Extrapulmonary tuberculosis in Kabul, Afghanistan: a hospital-based retrospective review.

  2010cites this paper
• An Outbreak of Hepatic Veno-Occlusive Disease in Western Afghanistan Associated with Exposure to Wheat Flour Contaminated with Pyrrolizidine Alkaloids

  2010influential citation
• Pyrrolizidine alkaloids - chemistry, biosynthesis, pathway, toxicity, safety and perspectives of medicinal usage

  2009cites this paper
• Toxicity profile of pyrrolizidine alkaloid-containing medicinal plants : Emphasis on Senecio species

  2009cites this paper
• Final report on carcinogens background document for riddelliine.

  2008cites this paper
• Senecio latifolius induces in vitro hepatocytotoxicity in a human cell line.

  2007cites this paper
• Safety issues associated with herbal ingredients.

  2005cites this paper
• Pyrrolizidine Alkaloids—Genotoxicity, Metabolism Enzymes, Metabolic Activation, and Mechanisms

  2004cites this paper
• Pyrrolizidine alkaloids in foods.

  2003cites this paper
• Honey from plants containing pyrrolizidine alkaloids: a potential threat to health.

  2002cites this paper
• Toxic injury to hepatic sinusoids: sinusoidal obstruction syndrome (veno-occlusive disease).

  2002cites this paper
• Toxic Injury to Hepatic Sinusoids: Sinusoidal Obstruction Syndrome (Veno-Occlusive Disease)

  2002cites this paper
• Human carcinogenesis and bracken fern: a review of the evidence.

  2002cites this paper
• Toxic pyrrolyzidine alkaloids from three mongolian plants. a possible risk for cattle poisoning.

  2002cites this paper
• GENOTOXIC PYRROLIZIDINE ALKALOIDS AND PYRROLIZIDINE ALKALOID N-OXIDES—MECHANISMS LEADING TO DNA ADDUCT FORMATION AND TUMORIGENICITY

  2001cites this paper
• Pyrrolizidine Poisoning: A Neglected Area in Human Toxicology

  2001cites this paper
• Medicinal plants in China containing pyrrolizidine alkaloids.

  2000cites this paper
• Pyrrolizidine alkaloid plants, metabolism and toxicity.

  1999cites this paper
• Pyrrolizidine alkaloids in human diet.

  1999cites this paper
• Safety of botanicals: historical perspective.

  1998cites this paper
• Pyrrolizidine alkaloid-induced depletion of taurine from rat liver in vivo and in vitro.

  1998cites this paper
• Role of copper in Indian childhood cirrhosis.

  1998cites this paper
• Hepatic circulation and toxicology.

  1997cites this paper
• Fatal hepatic veno-occlusive disease in a newborn infant.

  1997cites this paper
• Noncirrhotic portal hypertension.

  1997cites this paper
• Fatal Hepatic Veno-Occlusive Disease in a Newborn Infant

  1997cites this paper
• Effects of taurine and guanidinoethane sulfonate on toxicity of the pyrrolizidine alkaloid monocrotaline.

  1996cites this paper
• Effect of taurine on toxicity of the pyrrolizidine alkaloid monocrotaline in rats.

  1996cites this paper
• The effect of the pyrrolizidine alkaloids, monocrotaline and trichodesmine, on tissue pyrrole binding and glutathione metabolism in the rat.

  1995cites this paper
• Medicinal plants in Europe containing pyrrolizidine alkaloids.

  1995cites this paper
• The comparative metabolism of the four pyrrolizidine alkaloids, seneciphylline, retrorsine, monocrotaline, and trichodesmine in the isolated, perfused rat liver.

  1995cites this paper
• Relationship between glutathione concentration and metabolism of the pyrrolizidine alkaloid, monocrotaline, in the isolated, perfused liver.

  1995cites this paper
• Dietary pulmonary hypertension.

  1994cites this paper
• Exploration of the pulmonary circulation. Festschrift to Professor Donald Heath.

  1994cites this paper
• The Budd-Chiari syndrome and hepatic veno-occlusive disease. Recognition and treatment.

  1990cites this paper
• Comfrey herb tea and hepatic veno-occlusive disease.

  1989cites this paper
• Comfrey herb tea-induced hepatic veno-occlusive disease.

  1989cites this paper
• Drug-induced vascular and sinusoidal lesions of the liver.

  1988cites this paper
• Hypothesis: plant and fungal biocides, copper and Indian childhood liver disease.

  1987cites this paper
• Genotoxicity of a variety of pyrrolizidine alkaloids in the hepatocyte primary culture-DNA repair test using rat, mouse, and hamster hepatocytes.

  1985cites this paper
• Estimated intakes of pyrrolizidine alkaloids by humans. A comparison with dose rates causing tumors in rats.

  1983cites this paper
• An analysis of hepatic venocclusive disease and centrilobular hepatic degeneration following bone marrow transplantation.

  1980cites this paper
• Role of copper in Indian childhood cirrhosis 1 , 2

  year unknowncites this paper