The involvement of progesterone in the onset of human labour.

No abstract is available for this paper.

• Publication year

  2003

• Venue

  European Journal of Obstetrics, Gynecology, and Reproductive Biology

• Publication date

  2003-06-10

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0301-2115(02)00422-0PMID 12781407
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Progesterone receptor Localization and Isoforms in Myometrium, Decidua, and Fetal Membranes From Rhesus Macaques: Evidence for Function Progresterone Withdrawal at Parturtion

  2002cited by this paper
• Progesterone withdrawal and estrogen activation in human parturition are coordinated by progesterone receptor A expression in the myometrium.

  2002cited by this paper
• Perspective: female steroid hormone action.

  2001cited by this paper
• Human labour is associated with nuclear factor-kappaB activity which mediates cyclo-oxygenase-2 expression and is involved with the 'functional progesterone withdrawal'.

  2001cited by this paper
• Nongenomic action of steroids in myometrial contractility

  2001cited by this paper
• Influence of 5α- and 5β-reduced progestins on the contractility of isolated human myometrium at term

  2001cited by this paper
• Interactions between progesterone receptor isoforms in myometrial cells in human labour.

  2001cited by this paper
• Influence of 5alpha- and 5beta-reduced progestins on the contractility of isolated human myometrium at term.

  2001cited by this paper
• Regulation of the Oxytocin Receptor in Bovine Reproductive Tissues and the Role of Steroids

  2000cited by this paper
• Subgroup of reproductive functions of progesterone mediated by progesterone receptor-B isoform.

  2000cited by this paper
• NF-kappaB and AP-1 are required for cyclo-oxygenase 2 gene expression in amnion epithelial cell line (WISH).

  2000cited by this paper
• The Opposing Transcriptional Activities of the Two Isoforms of the Human Progesterone Receptor Are Due to Differential Cofactor Binding

  2000cited by this paper
• Progesterone receptor expression in the human placenta.

  1999cited by this paper
• The parturition defect in steroid 5alpha-reductase type 1 knockout mice is due to impaired cervical ripening.

  1999cited by this paper
• Expression of cyclo-oxygenase types-1 and -2 in human myometrium throughout pregnancy.

  1999cited by this paper
• Progesterone metabolite and spontaneous myometrial contractions in vitro.

  1999cited by this paper
• An N-terminal Inhibitory Function, IF, Suppresses Transcription by the A-isoform but Not the B-isoform of Human Progesterone Receptors*

  1998cited by this paper
• Oxytocin and vasopressin 1a receptor gene expression in the cycling or pregnant human uterus.

  1998cited by this paper
• Inhibition of oxytocin receptor function by direct binding of progesterone

  1998cited by this paper
• The Demonstration of Progesterone, but not of Estrogen, Receptors in the Developing Human Placenta

  1997cited by this paper
• Evidence for Involvement of NF-κB in the Transcriptional Control of COX-2 Gene Expression by IL-1β ☆

  1997cited by this paper
• Sex Steroid Receptors and Human Parturition

  1997cited by this paper
• Evidence for involvement of NF-kappaB in the transcriptional control of COX-2 gene expression by IL-1beta.

  1997cited by this paper
• Inhibition and augmentation of progesterone production during pregnancy: effects on parturition in rhesus monkeys.

  1997cited by this paper
• Cortisol blockade of progesterone: A possible molecular mechanism involved in the initiation of human labor

  1996cited by this paper
• Nongenomic effects of progesterone on human intestinal smooth muscle cells.

  1996cited by this paper
• Negative Interaction between the RelA(p65) Subunit of NF-B and the Progesterone Receptor (*)

  1996cited by this paper
• Myometrial Estradiol and Progesterone Receptor Changes in Preterm and Term Pregnancies

  1995cited by this paper
• Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities.

  1995cited by this paper
• The A and B isoforms of the human progesterone receptor operate through distinct signaling pathways within target cells

  1994cited by this paper
• A third transactivation function (AF3) of human progesterone receptors located in the unique N-terminal segment of the B-isoform.

  1994cited by this paper
• Immunohistochemical localization of estradiol and progesterone receptors in human uterus throughout pregnancy: expression in endometrial blood vessels.

  1994cited by this paper
• Human progesterone receptor A form is a cell- and promoter-specific repressor of human progesterone receptor B function.

  1993cited by this paper
• Mifepristone (RU486) alone or in combination with a prostaglandin analogue for termination of early pregnancy: a review.

  1991cited by this paper
• Two distinct estrogen‐regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B.

  1990cited by this paper
• Enzyme immunoassay of oestrogen and progesterone receptors in uterine and intrauterine tissue during human pregnancy and labour.

  1990cited by this paper
• Progesterone and oestradiol levels and cytoplasmic receptor concentrations in the human myometrium at term, before labour and during labour.

  1988cited by this paper
• Daily hormonal changes in the maternal, fetal, and amniotic fluid compartments before parturition in a primate species.

  1984cited by this paper
• Estrogen and progesterone receptor and hormone levels in human myometrium and placenta in term pregnancy.

  1984cited by this paper
• Oxytocin receptors in the human uterus during pregnancy and parturition.

  1984cited by this paper
• Cytoplasmic and nuclear progestin receptors in human myometrium during the menstrual cycle and in pregnancy at term.

  1979cited by this paper
• New progesterone metabolites in human myometrium.

  1977cited by this paper
• Mechanism of action of glucocorticoids in induction of ovine parturition: effect on placental steroid metabolism.

  1975cited by this paper
• Plasma estrone, estradiol, estriol, progesterone, and 17-hydroxyprogesterone in human pregnancy. I. Normal pregnancy.

  1972cited by this paper
• Metabolism of progesterone in human myometrium.

  1970cited by this paper
• Metabolism of Progesterone in Human Myometrium

  1969cited by this paper
• The effect of progesterone on the human uterus.

  1965cited by this paper

• Maternal-fetal conflict and the timing of birth

  2025cites this paper
• LC-MS/MS quantitation of the primary reduced metabolites of progesterone in serum during the third trimester of human pregnancy reveals a potential role for 20β-hydroxyprogesterone and 5β-dihydroprogesterone in functional progesterone withdrawal.

  2025cites this paper
• Promegestone Prevents Lipopolysaccharide-Induced Cervical Remodeling in Pregnant Mice

  2025cites this paper
• Kir7.1 is the physiological target for hormones and steroids that regulate uteroplacental function

  2023cites this paper
• 20α-Hydroxysteroid Dehydrogenase Expression in the Human Myometrium at Term and Preterm Birth: Relationships to Fetal Sex and Maternal Body Mass Index

  2023cites this paper
• Regulation of 20α-Hydroxysteroid Dehydrogenase Expression in Term Pregnant Human Myometrium Ex Vivo

  2023cites this paper
• Immune-metabolic adaptations in pregnancy: A potential stepping-stone to sepsis

  2022cites this paper
• Identification of unusual oxysterols biosynthesised in human pregnancy by charge-tagging and liquid chromatography - mass spectrometry

  2022cites this paper
• Can maternal hormones play a significant role in delivery mode?

  2022cites this paper
• What Do We Know about Classical and Non-Classical Progesterone Receptors in the Human Female Reproductive Tract? A Review

  2021cites this paper
• Landscape of Preterm Birth Therapeutics and a Path Forward

  2021cites this paper
• Histone Deacetylase Inhibitors: Providing New Insights and Therapeutic Avenues for Unlocking Human Birth

  2021cites this paper
• The selective progesterone receptor modulator, Promegestone, delays term parturition and prevents systemic inflammation-mediated preterm birth in mice.

  2021cites this paper
• Copolymer Composition and Nanoparticle Configuration Enhance in vitro Drug Release Behavior of Poorly Water-soluble Progesterone for Oral Formulations

  2020cites this paper
• The impact of progesterone and RU-486 on classic pro-labour proteins & contractility in human myometrial tissues during 24-hour exposure to tension & Interleukin-1β.

  2020cites this paper
• Androgen Signaling in the Placenta

  2020cites this paper
• The Regulation of Uterine Function During Parturition: an Update and Recent Advances

  2020cites this paper
• Liver Enzyme Elevation in Pregnant Women Receiving Antiretroviral Therapy in the ANRS-French Perinatal Cohort

  2019cites this paper
• Prenatal administration of progestogens for preventing spontaneous preterm birth in women with a multiple pregnancy.

  2019cites this paper
• Marantodes pumilum (Blume) Kuntze (Kacip Fatimah) stimulates uterine contraction in rats in post-partum period.

  2019cites this paper
• The Link Between Human Menstruation and Placental Delivery: A Novel Evolutionary Interpretation

  2019cites this paper
• Epigenetic regulation of progesterone receptors and the onset of labour.

  2019cites this paper
• Effect of copolymer composition on particle morphology and release behavior in vitro using progesterone

  2018cites this paper
• Preterm Labour

  2018cites this paper
• Associations of Immunological Markers and Anthropometric Measures with Linear and Nonlinear Electrohysterographic Parameters at Term Active Labor

  2018cites this paper
• Modulation of Human Sperm Capacitation by Progesterone, Estradiol, and Luteinizing Hormone

  2017cites this paper
• Modulation of Progesterone Receptor Isoform Expression in Pregnant Human Myometrium

  2017cites this paper
• Women Serum Concentrations of the IL-10 Family of Cytokines and IFN-γ Decrease from the Third Trimester of Pregnancy to Active Labor

  2017cites this paper
• The value of oral micronized progesterone in the prevention of recurrent spontaneous preterm birth: a randomized controlled trial

  2017cites this paper
• Role of oral micronized progesterone versus vaginal progesterone for prevention of preterm labour

  2017cites this paper
• Prenatal administration of progestogens for preventing spontaneous preterm birth in women with a singleton pregnancy

  2017cites this paper
• Characterization of Maternal and Fetal CYP3A-Mediated Progesterone Metabolism

  2017cites this paper
• Prenatal administration of progestogens for preventing spontaneous preterm birth in women with a multiple pregnancy.

  2017cites this paper
• Population differences and the effect of vaginal progesterone on preterm birth in women with threatened preterm labor*

  2016cites this paper
• Prenatal administration of progestogens for preventing preterm birth in women with a multiple pregnancy

  2016cites this paper
• Aromatase: Contributions to Physiology and Disease in Women and Men.

  2016cites this paper
• Risk assessment and management to prevent preterm birth.

  2016cites this paper
• Spontaneous Preterm Birth in Multiples

  2015cites this paper
• A randomised controlled double‐blind clinical trial of 17‐hydroxyprogesterone caproate for the prevention of preterm birth in twin gestation (PROGESTWIN): evidence for reduced neonatal morbidity

  2015cites this paper
• Enhanced Human Decidual Cell-Expressed FKBP51 May Promote Labor-Related Functional Progesterone Withdrawal.

  2015cites this paper
• Progesteron zur Prävention der Frühgeburt – Evidenz-basierte Indikationen

  2015cites this paper
• Progesterone for the Prevention of Preterm Birth

  2014cites this paper
• 16-week successful tocolysis with three agents on a twin gestation: case report and literature review

  2014cites this paper
• Progesterone Elicits an Inhibitory Effect upon LPS‐Induced Innate Immune Response in Pre‐Labor Human Amniotic Epithelium

  2014cites this paper
• Strategies to Prevent Preterm Birth

  2014cites this paper
• Efficacy of 17α- hydroxy progestrone on decreasing preterm labor in ART pregnancies: A randomized clinical trial

  2013cites this paper
• Matched sample comparison of intramuscular versus vaginal micronized progesterone for prevention of preterm birth

  2013cites this paper
• The Rebirth of Progesterone in the Prevention of Preterm Labor

  2013cites this paper
• Prenatal administration of progesterone for preventing preterm birth in women considered to be at risk of preterm birth.

  2013cites this paper
• Salivary progesterone as a biochemical marker to predict early preterm birth in asymptomatic high‐risk women

  2013cites this paper
• Progesteron zur Prävention der Frühgeburt – Evidenz-basierte Indikationen Progesterone for Prevention of Preterm Birth – Evidence-based Indications

  2013cites this paper
• Progesterone to prevent preterm birth in twin gestations: what is the next step forward?

  2013cites this paper
• Prevention of preterm delivery by 17 alpha-hydroxyprogesterone caproate in asymptomatic twin pregnancies with a short cervix: a randomized controlled trial.

  2013cites this paper
• Crinone versus duphaston in the prevention and treatment of threatened preterm labour

  2012cites this paper
• [Progesterone receptor-mediated molecular mechanisms on mammalian female reproduction].

  2012cites this paper
• Research on the Expression of HOXA10 in Placental Villi during the Onset of Labor

  2012cites this paper
• Outcome of Vaginal Progesterone as a Tocolytic Agent: Randomized Clinical Trial

  2012cites this paper
• Prevention of preterm delivery after successful tocolysis in preterm labor by 17 alpha-hydroxyprogesterone caproate: a randomized controlled trial.

  2012cites this paper
• The role of inflammation and infection in preterm birth.

  2011cites this paper
• Remodeling of the Cervix and Parturition in Mice Lacking the Progesterone Receptor B Isoform1

  2011cites this paper
• Increased Expression of Enzymes for Sphingosine 1-Phosphate Turnover and Signaling in Human Decidua During Late Pregnancy1

  2010cites this paper
• Toll-like receptors and mechanism of human parturition

  2010cites this paper
• Human labor is associated with reduced decidual cell expression of progesterone, but not glucocorticoid, receptors.

  2010cites this paper
• The onset of human parturition

  2010cites this paper
• Depletion of calcium stores contributes to progesterone-induced attenuation of calcium signaling of G protein-coupled receptors

  2010cites this paper
• MAINTENANCE THERAPY BY VAGINAL PROGESTERONE AFTER THREATENED IDIOPATHIC PRETERM LABOR: A RANDOMIZED PLACEBO-CONTROLLED DOUBLE-BLIND TRIAL

  2010cites this paper
• Interplay between polypyrimidine tract binding protein-associated splicing factor and human myometrial progesterone receptors.

  2009cites this paper
• Biology of Parturition

  2009cites this paper
• Progesterone Withdrawal Promotes Remodeling Processes in the Nonpregnant Mouse Cervix1

  2009cites this paper
• Systematic review of progesterone for the prevention of preterm birth in singleton pregnancies

  2009cites this paper
• The role of progesterone in prevention of preterm birth

  2009cites this paper
• A Short Cervical Length in Pregnancy: Management Options

  2009cites this paper
• Progesterone for the Prevention of Preterm Birth: A Systematic Review

  2008cites this paper
• Prevention of Preterm Birth

  2008cites this paper
• Non-genomic progesterone actions in female reproduction.

  2008cites this paper
• Progesterone receptor profile in the decidua and fetal membrane.

  2007cites this paper
• Neuroimmunology of Pregnancy-Related Sleep Disturbances

  2007cites this paper
• Physiologie der Geburt

  2007cites this paper
• [Immunological role of progesterone in the maintenance of pregnancy].

  2007cites this paper
• Examining the spatio-temporal expression of mRNA encoding the membrane-bound progesterone receptor-alpha isoform in human cervix and myometrium during pregnancy and labour.

  2006cites this paper
• SMOKING AND PREGNANCY, with special reference to preterm birth and the feto-placental unit

  2006cites this paper
• Prenatal administration of progesterone for preventing preterm birth.

  2006cites this paper
• Mechanisms of progesterone action in inhibiting prematurity

  2006cites this paper
• Progesterone enhances the tocolytic effect of ritodrine in isolated pregnant human myometrium.

  2005cites this paper
• Regulated expression of putative membrane progestin receptor homologues in human endometrium and gestational tissues.

  2005influential citation
• Progesterone supplementation for preventing preterm birth: a systematic review and meta‐analysis

  2005influential citation
• The Molecular Pathophysiology of Bacterially Induced Preterm Labor: Insights From the Murine Model

  2005cites this paper
• Progesterone receptors in the human uterus and their possible role in parturition.

  2005cites this paper
• Progesterone receptor expression in human decidua and fetal membranes before and after contractions: possible mechanism for functional progesterone withdrawal.

  2005cites this paper
• Steroid hormone synthesis in pregnancy.

  2004cites this paper
• Effect of Proteasome Pathway on Initiation of Mouse Labor Induced by Antiprogesterone

  2004cites this paper
• Bmc Pregnancy and Childbirth Progesterone after Previous Preterm Birth for Prevention of Neonatal Respiratory Distress Syndrome (progress): a Randomised Controlled Trial

  year unknowncites this paper