Small Jab1‐containing subcomplex is regulated in an anchorage‐ and cell cycle‐dependent manner, which is abrogated by ras transformation

No abstract is available for this paper.

• Publication year

  2005

• Venue

  FEBS Letters

• Publication date

  2005-02-14

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.febslet.2004.12.076PMID 15710389
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The Jab1/COP9 signalosome subcomplex is a downstream mediator of Bcr-Abl kinase activity and facilitates cell-cycle progression.

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• Skp2-mediated degradation of p27 regulates progression into mitosis.

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• Multiple Functions of Jab1 Are Required for Early Embryonic Development and Growth Potential in Mice*

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• Prognostic significance of localized p27Kip1 and potential role of Jab1/CSN5 in pancreatic cancer.

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• Distinct aerobic and hypoxic mechanisms of HIF-α regulation by CSN5

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• Expression of cell cycle inhibitor p27Kip1 and its inactivator Jab1 in melanocytic lesions

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• The COP9 signalosome: an assembly and maintenance platform for cullin ubiquitin ligases?

  2003cited by this paper
• 14-3-3 sigma possibly plays a constitutive role in papillary carcinoma, but not in follicular tumor of the thyroid.

  2003cited by this paper
• The COP9 signalosome.

  2003cited by this paper
• Expression of p27(Kip1) and c-Jun activation binding protein 1 are inversely correlated in systemic anaplastic large cell lymphoma.

  2003cited by this paper
• Expression of p27Kip1 and c-Jun Activation Binding Protein 1 Are Inversely Correlated in Systemic Anaplastic Large Cell Lymphoma

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• Jun activation domain binding protein 1 expression is associated with low p27(Kip1)levels in node-negative breast cancer.

  2003cited by this paper
• Jun activation domain-binding protein 1 expression in malignant lymphoma of the thyroid: its linkage to degree of malignancy and p27 expression.

  2003cited by this paper
• Skp2 and Jab1 Expression Are Associated with Inverse Expression of p27KIP1 and Poor Prognosis in Oral Squamous Cell Carcinomas

  2003cited by this paper
• Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome

  2003cited by this paper
• 14-3-3 sigma possibly plays a constitutive role in papillary carcinoma, but not in follicular tumor of the thyroid.

  2003cited by this paper
• Jun activation domain-binding protein 1 expression in breast cancer inversely correlates with the cell cycle inhibitor p27(Kip1).

  2003cited by this paper
• COP9 signalosome: a multifunctional regulator of SCF and other cullin-based ubiquitin ligases.

  2003cited by this paper
• The Cytoplasmic Shuttling and Subsequent Degradation of p27Kip1 Mediated by Jab1/CSN5 and the COP9 Signalosome Complex*

  2002cited by this paper
• Deletion mutants in COP9/signalosome subunits in fission yeast Schizosaccharomyces pombe display distinct phenotypes.

  2002cited by this paper
• Role of Predicted Metalloprotease Motif of Jab1/Csn5 in Cleavage of Nedd8 from Cul1

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• Expression of Cyclin‐dependent Kinase Inhibitor p27/Kipl and AP‐1 Coactivator p38/Jabl Correlates with Differentiation of Embryonal Rhabdomyosarcoma

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• COP9 signalosome subunits 4 and 5 regulate multiple pleiotropic pathways in Drosophila melanogaster.

  2002cited by this paper
• The COP9 signalosome: at the interface between signal transduction and ubiquitin-dependent proteolysis.

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• Protein stability: the COP9 signalosome gets in on the act.

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  2001cited by this paper
• COP9 signalosome‐specific phosphorylation targets p53 to degradation by the ubiquitin system

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  2001cited by this paper
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  2000cited by this paper
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  1998influential reference
• Arabidopsis Homologs of a c-Jun Coactivator Are Present Both in Monomeric Form and in the COP9 Complex, and Their Abundance Is Differentially Affected by the Pleiotropic cop/det/fus Mutations

  1998cited by this paper

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  2020cites this paper
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  2014cites this paper
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  2013cites this paper
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  2007influential citation
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• The Emerging Role of the COP 9 Signalosome in Cancer

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• Author Index

  2005cites this paper
• The Emerging Role of the COP9 Signalosome in Cancer

  2005cites this paper