A possible pathogenesis for Alzheimer's disease: craniomaxillofacial dysfunction leading to localized cerebrospinal fluid stasis.

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Medical Hypotheses

• Publication date

  2009-02-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/j.mehy.2008.09.044PMID 19026494
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Molecular Pathology of Alzheimer's Disease

  2013cited by this paper
• eMedicine

  2009cited by this paper
• The Amyloid Hypothesis of Alzheimer ’ s Disease : Progress and Problems on the Road to Therapeutics

  2009cited by this paper
• Current and future uses of neuroimaging for cognitively impaired patients.

  2008cited by this paper
• Midlife activity predicts risk of dementia in older male twin pairs

  2008cited by this paper
• Olfaction in patients with mild cognitive impairment and Alzheimer's disease.

  2008cited by this paper
• Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid β-peptide

  2007cited by this paper
• Aβ Oligomers – a decade of discovery

  2007cited by this paper
• Three weeks of running wheel exposure improves cognitive performance in the aged Tg2576 mouse.

  2007cited by this paper
• 3D maps from multiple MRI illustrate changing atrophy patterns as subjects progress from mild cognitive impairment to Alzheimer's disease.

  2007cited by this paper
• Tooth loss, dementia and neuropathology in the Nun study.

  2007cited by this paper
• Exercise Is Associated with Reduced Risk for Incident Dementia among Persons 65 Years of Age and Older

  2006cited by this paper
• Olfaction in neurodegenerative disorder.

  2006cited by this paper
• Review of "The Blood-Cerebrospinal Fluid Barrier" by Wei Zheng and Adam Chodobski (editors)

  2006cited by this paper
• Filling the Gaps in the Aβ Cascade Hypothesis of Alzheimers Disease

  2006cited by this paper
• PET of brain amyloid and tau in mild cognitive impairment.

  2006cited by this paper
• Beta-amyloid, oxidative stress and down syndrome.

  2006cited by this paper
• Potentially modifiable risk factors for dementia in identical twins

  2006cited by this paper
• Filling the gaps in the abeta cascade hypothesis of Alzheimer's disease.

  2006cited by this paper
• Voluntary Exercise Decreases Amyloid Load in a Transgenic Model of Alzheimer's Disease

  2005cited by this paper
• Preventing Alzheimer's: A Lifelong Commitment?

  2005cited by this paper
• Neuroscience. Preventing Alzheimer's: a lifelong commitment?

  2005cited by this paper
• Exercise and cognitive function.

  2005cited by this paper
• Apolipoprotein ε4 is associated with more rapid decline in odor identification than in odor threshold or Dementia Rating Scale scores

  2005cited by this paper
• Traffic Noise and Risk of Myocardial Infarction

  2005cited by this paper
• The Effect of Exercise on Hippocampal Integrity: Review of Recent Research

  2005cited by this paper
• Modulatory effects of pH, Cu+2 and sheet breakers on aggregation of amyloid peptides.

  2005cited by this paper
• Olfactory involvement in aging and Alzheimer's disease: An autopsy study

  2005cited by this paper
• Play and Exercise Protect Mouse Brain From Amyloid Buildup

  2005cited by this paper
• Fluid Compartments of the Central Nervous System

  2005cited by this paper
• Exercise primes a molecular memory for brain-derived neurotrophic factor protein induction in the rat hippocampus.

  2005cited by this paper
• Occupational Exposure to Noise and Mortality From Acute Myocardial Infarction

  2005cited by this paper
• Holes in the head: Evolutionary interpretations of the paranasal sinuses in catarrhines

  2004influential reference
• Voluntary exercise protects against stress-induced decreases in brain-derived neurotrophic factor protein expression.

  2004cited by this paper
• Exercise Level and Cognitive Decline: The MoVIES Project

  2004cited by this paper
• Effects of the ApoE ε4 allele on olfactory function in Down Syndrome

  2004cited by this paper
• Exercise, aging, and Alzheimer disease.

  2004cited by this paper
• Effects of the ApoE epsilon4 allele on olfactory function in Down syndrome.

  2004cited by this paper
• The effects of exercise training on elderly persons with cognitive impairment and dementia: a meta-analysis.

  2004cited by this paper
• Early Olfactory Involvement in Alzheimer’s Disease

  2003cited by this paper
• [Down syndrome].

  2003cited by this paper
• Aging, Amyloid, and Alzheimer's Disease: A Perspective in Honor of Carl Cotman

  2003cited by this paper
• Assessment of low-flow CSF drainage as a treatment for AD: Results of a randomized pilot study

  2003cited by this paper
• Olfactory impairment increases as a function of age in persons with Down syndrome.

  2002cited by this paper
• The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics

  2002cited by this paper
• Plasma homocysteine as a risk factor for dementia and Alzheimer's disease.

  2002cited by this paper
• Intraneuronal Abeta42 accumulation in Down syndrome brain.

  2002cited by this paper
• Exercise: a behavioral intervention to enhance brain health and plasticity.

  2002cited by this paper
• Alzheimer's Disease Is a Synaptic Failure

  2002cited by this paper
• Hippocampal brain‐derived neurotrophic factor gene regulation by exercise and the medial septum

  2002cited by this paper
• Exercise Enhances and Protects Brain Function

  2002cited by this paper
• Assessment of low-flow CSF drainage as a treatment for AD

  2002cited by this paper
• The cerebrospinal fluid production rate is reduced in dementia of the Alzheimer's type.

  2002cited by this paper
• Intraneuronal Aβ42 accumulation in Down syndrome brain

  2002cited by this paper
• Plasma Homocysteine as a Risk Factor for Dementia and Alzheimer's Disease

  2002cited by this paper
• Evidence for involvement of dysfunctional teeth in the senile process in the hippocampus of SAMP8 mice.

  2001cited by this paper
• Effects of exercise on gene-expression profile in the rat hippocampus.

  2001cited by this paper
• Targeting small Aβ oligomers: the solution to an Alzheimer's disease conundrum?

  2001influential reference
• The cerebrospinal fluid production rate is reduced in dementia of the Alzheimer’s type

  2001cited by this paper
• Oxidation of Abeta and plaque biogenesis in Alzheimer's disease and Down syndrome.

  2001cited by this paper
• Oxidation of Aβ and Plaque Biogenesis in Alzheimer's Disease and Down Syndrome

  2001cited by this paper
• Risk factors for Alzheimer's disease: a population-based, longitudinal study in Manitoba, Canada.

  2001cited by this paper
• Olfactory deficits in patients with mild cognitive impairment predict Alzheimer's disease at follow-up.

  2000cited by this paper
• Impairment of spatial memory and changes in astroglial responsiveness following loss of molar teeth in aged SAMP8 mice.

  2000cited by this paper
• Morphological alterations of the choroid plexus in late-onset Alzheimer’s disease

  2000cited by this paper
• The Brain's Microenvironment, Early Functional Loss, and the Conversion to Alzheimer's Disease

  2000cited by this paper
• Neuroprotective signaling and the aging brain: take away my food and let me run.

  2000cited by this paper
• The aging skeleton

  1999cited by this paper
• The Aging Maxillofacial Skeleton

  1999cited by this paper
• Reduced mastication stimulates impairment of spatial memory and degeneration of hippocampal neurons in aged SAMP8 mice.

  1999cited by this paper
• Dramatic Aggregation of Alzheimer Aβ by Cu(II) Is Induced by Conditions Representing Physiological Acidosis*

  1998cited by this paper
• Relationship of senescence of cerebrospinal fluid circulatory system to dementias of the aged.

  1998cited by this paper
• Olfactory dysfunction in Down's Syndrome.

  1996cited by this paper
• In vitro growth of Alzheimer's disease beta-amyloid plaques displays first-order kinetics.

  1996cited by this paper
• Odor identification as an early marker for Alzheimer's disease: impact of lexical functioning and detection sensitivity.

  1995cited by this paper
• Dental amalgam and cognitive function in older women: findings from the Nun Study.

  1995cited by this paper
• Cortical CSF volume fluctuations by MRI in brain aging, dementia and hydrocephalus.

  1994cited by this paper
• Anosmia in Alzheimer Disease

  1994cited by this paper
• A case-control study of Alzheimer's disease in Japan--significance of life-styles.

  1994cited by this paper
• Solution conformations and aggregational properties of synthetic amyloid beta-peptides of Alzheimer's disease. Analysis of circular dichroism spectra.

  1992cited by this paper
• Analysis of circular dichroism spectra.

  1992cited by this paper
• Alzheimer's disease: the amyloid cascade hypothesis.

  1992cited by this paper
• Amyloid deposition as the central event in the aetiology of Alzheimer's disease.

  1991cited by this paper
• The molecular pathology of Alzheimer's disease.

  1991cited by this paper
• The nature and course of olfactory deficits in Alzheimer's disease.

  1991cited by this paper
• Cerebrospinal fluid production is reduced in healthy aging

  1990cited by this paper
• Olfactory thresholds are associated with degree of dementia in Alzheimer's disease.

  1990cited by this paper
• Pathological changes in olfactory neurons in patients with Alzheimer's disease

  1989cited by this paper
• Presence of both odor identification and detection deficits in Alzheimer's disease.

  1987cited by this paper
• Changes at the base of skull and cervical spine in Down syndrome.

  1986cited by this paper
• Olfactory dysfunction in Alzheimer's disease and Parkinson's disease.

  1985cited by this paper
• DSM-III Case Book. A Learning Companion to the Diagnostic and Statistical Manual of Mental Disorders, 3rd Ed

  1982cited by this paper
• Craniofacial complex in the trisomy 21 syndrome (Down's syndrome).

  1971cited by this paper

• Vascular and respiratory impact in neurodegenerative diseases

  2017cites this paper
• Mechanical stress related to brain atrophy in Alzheimer's disease

  2016cites this paper
• Mechanical Stress as the Common Denominator between Chronic Inflammation, Cancer, and Alzheimer’s Disease

  2015cites this paper
• The micron stroke hypothesis of Alzheimer's disease and dementia.

  2012cites this paper
• Reciprocal influence of masticatory apparatus, craniofacial structure and whole body homeostasis.

  2012cites this paper