Thermosensitive liposomes for the delivery of gemcitabine and oxaliplatin to tumors.

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Molecular Pharmaceutics

• Publication date

  2013-11-11

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1021/mp400321ePMID 24152292
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Characterization of Permeability, Stability and Anti-HIV-1 Activity of Decitabine and Gemcitabine Divalerate Prodrugs

  2014cited by this paper
• Capecitabine and oxaliplatin in combination as first- or second-line therapy for metastatic breast cancer: a Wisconsin Oncology Network trial

  2013cited by this paper
• Liposomes, a promising strategy for clinical application of platinum derivatives

  2013cited by this paper
• Gemcitabine-loaded biocompatible nanocapsules for the effective treatment of human cancer.

  2013cited by this paper
• Mild hyperthermia triggered doxorubicin release from optimized stealth thermosensitive liposomes improves intratumoral drug delivery and efficacy.

  2013cited by this paper
• Oral delivery of anticancer drugs: challenges and opportunities.

  2013cited by this paper
• Novel temperature-triggered liposome with high stability: formulation, in vitro evaluation, and in vivo study combined with high-intensity focused ultrasound (HIFU).

  2013cited by this paper
• Hyperthermia-induced drug targeting

  2013cited by this paper
• Thermosensitive liposomes for localized delivery and triggered release of chemotherapy.

  2013cited by this paper
• Comparison of Conventional Chemotherapy, Stealth Liposomes and Temperature-Sensitive Liposomes in a Mathematical Model

  2012cited by this paper
• Hyperthermia-triggered drug delivery from temperature-sensitive liposomes using MRI-guided high intensity focused ultrasound.

  2012cited by this paper
• Overcoming limitations in nanoparticle drug delivery: triggered, intravascular release to improve drug penetration into tumors.

  2012cited by this paper
• Thermosensitive Liposomes in Cancer Therapy

  2012cited by this paper
• A thermosensitive liposome prepared with a Cu²⁺ gradient demonstrates improved pharmacokinetics, drug delivery and antitumor efficacy.

  2012cited by this paper
• Oxaliplatin long-circulating liposomes improved therapeutic index of colorectal carcinoma

  2011cited by this paper
• Intracellular targeting delivery of liposomal drugs to solid tumors based on EPR effects.

  2011cited by this paper
• Nanoscale Drug Delivery and Hyperthermia: The Materials Design and Preclinical and Clinical Testing of Low Temperature-Sensitive Liposomes Used in Combination with Mild Hyperthermia in the Treatment of Local Cancer.

  2011cited by this paper
• Liposome based delivery systems in pancreatic cancer treatment: from bench to bedside.

  2011cited by this paper
• Gemcitabine-loaded innovative nanocarriers vs GEMZAR: Biodistribution, pharmacokinetic features and in vivo antitumor activity

  2011cited by this paper
• Efficient tumor regression by a single and low dose treatment with a novel and enhanced formulation of thermosensitive liposomal doxorubicin.

  2011cited by this paper
• Optimization of a novel and improved thermosensitive liposome formulated with DPPC and a Brij surfactant using a robust in vitro system.

  2011cited by this paper
• MRI monitoring of intratumoral drug delivery and prediction of the therapeutic effect with a multifunctional thermosensitive liposome.

  2011cited by this paper
• Preoperative/Neoadjuvant Therapy in Pancreatic Cancer: A Systematic Review and Meta-analysis of Response and Resection Percentages

  2010cited by this paper
• Hyperthermia and Thermosensitive Liposomes for Improved Delivery of Chemotherapeutic Drugs to Solid Tumors

  2010cited by this paper
• Gemcitabine-loaded PEGylated unilamellar liposomes vs GEMZAR: biodistribution, pharmacokinetic features and in vivo antitumor activity.

  2010cited by this paper
• Membrane transporters in drug development

  2010cited by this paper
• Oxaliplatin encapsulated in PEG-coated cationic liposomes induces significant tumor growth suppression via a dual-targeting approach in a murine solid tumor model.

  2009cited by this paper
• Chemoradiotherapy in the management of locally advanced pancreatic carcinoma: a qualitative systematic review.

  2009cited by this paper
• Antimetastatic Effects of Liposomal Gemcitabine and Empty Liposomes in an Orthotopic Mouse Model of Pancreatic Cancer

  2009cited by this paper
• Use of a passive equilibration methodology to encapsulate cisplatin into preformed thermosensitive liposomes.

  2008cited by this paper
• A new liposomal formulation of Gemcitabine is active in an orthotopic mouse model of pancreatic cancer accessible to bioluminescence imaging

  2008cited by this paper
• Simultaneous determination of gemcitabine and gemcitabine-squalene by liquid chromatography-tandem mass spectrometry in human plasma.

  2007cited by this paper
• Antitumor activity and pharmacokinetics of liposomes containing lipophilic gemcitabine prodrugs.

  2007cited by this paper
• Long-Circulating, Temperature-Sensitive and EGFR-Targeted Liposomes for Drugs Delivery

  2007cited by this paper
• Liposomal oxaliplatin in the treatment of advanced cancer: a phase I study.

  2006cited by this paper
• Effects of lipid segregation and lysolipid dissociation on drug release from thermosensitive liposomes.

  2005cited by this paper
• Predictive Value of Heparanase Expression in the Palliative Therapy of Pancreatic Cancer

  2005cited by this paper
• Kinetic behavior of urea is different from that of other water-soluble compounds: the case of the guanidino compounds.

  2005cited by this paper
• Novel Temperature-Sensitive Liposomes with Prolonged Circulation Time

  2004cited by this paper
• Measurement of the anti-cancer agent gemcitabine in human plasma by high-performance liquid chromatography.

  2003cited by this paper
• A new temperature-sensitive liposome for use with mild hyperthermia: characterization and testing in a human tumor xenograft model.

  2000cited by this paper
• Predictive value of preclinical toxicology studies for platinum anticancer drugs.

  1999cited by this paper
• Functional nucleoside transporters are required for gemcitabine influx and manifestation of toxicity in cancer cell lines.

  1998cited by this paper
• Thermosensitive Sterically Stabilized Liposomes: Formulation and in Vitro Studies on Mechanism of Doxorubicin Release by Bovine Serum and Human Plasma

  1995cited by this paper
• Kinetic analysis of P-glycoprotein-mediated doxorubicin efflux.

  1992cited by this paper
• Liposomes and local hyperthermia: selective delivery of methotrexate to heated tumors.

  1979cited by this paper
• Design of liposomes for enhanced local release of drugs by hyperthermia.

  1978cited by this paper

• Synthesis, characterization of ultrasmall gold nanocluster conjugated with Gemcitabine for anticancer activity

  2025cites this paper
• Nanostructures for site-specific delivery of oxaliplatin cancer therapy: Versatile nanoplatforms in synergistic cancer therapy

  2023cites this paper
• Hybrid Magnetic Lipid-Based Nanoparticles for Cancer Therapy

  2023cites this paper
• Biomedical and clinical applications of platinum-based nanohybrids: An update review.

  2023cites this paper
• Review of the Delivery Kinetics of Thermosensitive Liposomes

  2023influential citation
• Heat-activated nanomedicine formulation improves the anticancer potential of the HSP90 inhibitor luminespib in vitro

  2021cites this paper
• Gemcitabine Peptide-Based Conjugates and Their Application in Targeted Tumor Therapy

  2021cites this paper
• Design, Synthesis and Characterization of a Novel Type of Thermo-Responsible Phospholipid Microcapsule–Alginate Composite Hydrogel for Drug Delivery

  2020cites this paper
• Nanotechnology as a Platform for the Development of Injectable Parenteral Formulations: A Comprehensive Review of the Know-Hows and State of the Art

  2020cites this paper
• The effect of low‐ and high‐penetration light on localized cancer therapy

  2019cites this paper
• Heat-activated drug delivery increases tumor accumulation of synergistic chemotherapies.

  2019cites this paper
• Gemcitabine-loaded RGD modified liposome for ovarian cancer: preparation, characterization and pharmacodynamic studies

  2019cites this paper
• DDDT_A_211168 3281..3290

  2019cites this paper
• Tumor-specific delivery of gemcitabine with activatable liposomes.

  2019cites this paper
• Clinical Trials of Thermosensitive Nanomaterials: An Overview

  2019cites this paper
• Biocompatible tumor micro-environment responsive CS-g-PNIPAAm co-polymeric nanoparticles for targeted Oxaliplatin delivery

  2018cites this paper
• Experimental Basis for the Use of Hyperthermia in Oncology

  2018cites this paper
• Current update of a thermosensitive liposomes composed of DPPC and Brij78

  2018cites this paper
• Diels Alder-mediated release of gemcitabine from nanoparticles : developing improved methods for pancreatic cancer drug delivery

  2017cites this paper
• New pH-responsive gemini lipid derived co-liposomes for efficacious doxorubicin delivery to drug resistant cancer cells.

  2017cites this paper
• Cellular uptake and anti-tumor activity of gemcitabine conjugated with new amphiphilic cell penetrating peptides

  2017cites this paper
• Comparing the therapeutic potential of thermosensitive liposomes and hyperthermia in two distinct subtypes of breast cancer

  2017cites this paper
• To heat or not to heat: Challenges with clinical translation of thermosensitive liposomes

  2017cites this paper
• Tumor microenvironment determines response to a heat-activated thermosensitive liposome formulation of cisplatin in cervical carcinoma.

  2017cites this paper
• Effects of cell penetrating Notch inhibitory peptide conjugated to elastin-like polypeptide on glioblastoma cells

  2017cites this paper
• Multifunctional platinum-based nanoparticles for biomedical applications.

  2017cites this paper
• Revisiting the use of sPLA2‐sensitive liposomes in cancer therapy

  2017cites this paper
• Core–shell drug carriers: liposomes, polymersomes, and niosomes

  2017cites this paper
• Preclinical evaluation of paramagnetic temperature sensitive liposomes for image-guided drug delivery

  2017cites this paper
• A pH-sensitive stearoyl-PEG-poly(methacryloyl sulfadimethoxine)-decorated liposome system for protein delivery: An application for bladder cancer treatment.

  2016cites this paper
• Natural and synthetic polymers for drug delivery and targeting

  2016cites this paper
• Versatile Nanosystem-Based Cancer Theranostics: Design Inspiration and Predetermined Routing

  2016cites this paper
• Preparation, characterization, and efficacy of thermosensitive liposomes containing paclitaxel

  2016cites this paper
• Recent advances in drug delivery strategies for improved therapeutic efficacy of gemcitabine.

  2016cites this paper
• Review of current trends in enhancing bioavailability of poorly water soluble drugs by liposomal interventions

  2016influential citation
• Preparation and Evaluation of Oxaliplatin Thermosensitive Liposomes with Rapid Release and High Stability

  2016cites this paper
• Nanomedicines for advanced cancer treatments: Transitioning towards responsive systems.

  2016cites this paper
• Characterization and cytotoxicity studies of DPPC:M(2+) novel delivery system for cisplatin thermosensitivity liposome with improving loading efficiency.

  2015cites this paper
• ATP-responsive DNA-graphene hybrid nanoaggregates for anticancer drug delivery.

  2015cites this paper
• Light induced cytosolic drug delivery from liposomes with gold nanoparticles.

  2015cites this paper
• Acid-responsive PEGylated doxorubicin prodrug nanoparticles for neuropilin-1 receptor-mediated targeted drug delivery.

  2015cites this paper
• In vitro and in vivo antitumor activity of gemcitabine loaded thermosensitive liposomal nanoparticles and mild hyperthermia in pancreatic cancer.

  2015cites this paper
• DSPE-PEG: a distinctive component in drug delivery system.

  2015cites this paper
• Advancement in Gemcitabine Delivery for Cancer Treatment

  2015cites this paper
• Stimuli-Sensitive Liposomes: Lipids as Gateways for Cargo Release

  2015cites this paper
• Thermosensitive nanoplatforms for photothermal release of cargo from liposomes under intracellular temperature monitoring

  2015cites this paper
• Near‐Infrared Light‐Absorptive Stealth Liposomes for Localized Photothermal Ablation of Tumors Combined with Chemotherapy

  2015cites this paper
• Doxorubicin-loaded poly(lactic-co-glycolic acid) hollow microcapsules for targeted drug delivery to cancer cells

  2014cites this paper
• Applications of lipid based formulation technologies in the delivery of biotechnology-based therapeutics.

  2014cites this paper
• pH-sensitive stearoyl-PEG-poly(methacryloyl sulfadimethoxine) decorated liposomes for the delivery of gemcitabine to cancer cells.

  2014influential citation
• Thermosensitive liposomal drug delivery systems: state of the art review

  2014influential citation