D-amino acid oxidase generates agonists of the aryl hydrocarbon receptor from D-tryptophan.

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Chemical Research in Toxicology

• Publication date

  2009-10-27

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1021/tx900043sPMID 19860415PMCID PMC2923838
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Structural identification of Diindole agonists of the aryl hydrocarbon receptor derived from degradation of indole-3-pyruvic acid.

  2009cited by this paper
• D-amino acid formation in sterilized alkali-treated olives.

  2007cited by this paper
• The aryl hydrocarbon receptor and light

  2006cited by this paper
• Cellular distribution of D-serine, serine racemase and D-amino acid oxidase in the rat vestibular sensory epithelia.

  2006cited by this paper
• D-amino acids in the central nervous system in health and disease.

  2005cited by this paper
• Identification of the tryptophan photoproduct 6-formylindolo[3,2-b]carbazole, in cell culture medium, as a factor that controls the background aryl hydrocarbon receptor activity.

  2005influential reference
• D-amino-acid oxidase is involved in D-serine-induced nephrotoxicity.

  2005cited by this paper
• Sensitive determination of D-amino acids in mammals and the effect of D-amino-acid oxidase activity on their amounts.

  2005cited by this paper
• Gestational exposure of Ahr and Arnt hypomorphs to dioxin rescues vascular development.

  2004cited by this paper
• Role of Aryl Hydrocarbon Receptor-mediated Induction of the CYP1 Enzymes in Environmental Toxicity and Cancer*

  2004cited by this paper
• Serum amino acid concentrations in aging men and women

  2003cited by this paper
• Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals.

  2003cited by this paper
• Aspartate aminotransferase generates proagonists of the aryl hydrocarbon receptor.

  2003influential reference
• Stone.vp:CorelVentura 7.0

  2001cited by this paper
• Analysis of amino acids in human serum by isocratic reversed-phase high-performance liquid chromatography with electrochemical detection.

  2001cited by this paper
• The hsp90 Chaperone Complex Regulates Intracellular Localization of the Dioxin Receptor

  2001cited by this paper
• Portosystemic shunting and persistent fetal vascular structures in aryl hydrocarbon receptor-deficient mice.

  2000cited by this paper
• Ultraviolet-B exposure of human skin induces cytochromes P450 1A1 and 1B1.

  2000cited by this paper
• D-Amino acid oxidase: new findings

  2000cited by this paper
• Chemistry, nutrition, and microbiology of D-amino acids.

  1999influential reference
• Purification of serine racemase: biosynthesis of the neuromodulator D-serine.

  1999cited by this paper
• Induction of cytochrome P4501A1.

  1999cited by this paper
• Expression of ARNT, ARNT2, HIF1α, HIF2α and Ah receptor mRNAs in the developing mouse

  1998cited by this paper
• Expression of ARNT, ARNT2, HIF1 alpha, HIF2 alpha and Ah receptor mRNAs in the developing mouse.

  1998cited by this paper
• Constitutive Activation of the Aromatic Hydrocarbon Receptor

  1998cited by this paper
• Activation of the Ah receptor by tryptophan and tryptophan metabolites.

  1998cited by this paper
• Nuclear Localization and Export Signals of the Human Aryl Hydrocarbon Receptor*

  1998cited by this paper
• d-Serine as a Neuromodulator: Regional and Developmental Localizations in Rat Brain Glia Resemble NMDA Receptors

  1997cited by this paper
• Lesions of Aryl-hydrocarbon Receptor–deficient Mice

  1997cited by this paper
• Comparison of Ah receptor-mediated luciferase and ethoxyresorufin-O-deethylase induction in H4IIE cells: implications for their use as bioanalytical tools for the detection of polyhalogenated aromatic hydrocarbons.

  1996cited by this paper
• Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor.

  1996cited by this paper
• Characterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and development.

  1996cited by this paper
• D-serine, an endogenous synaptic modulator: localization to astrocytes and glutamate-stimulated release.

  1995cited by this paper
• Developmental expression of two members of a new class of transcription factors: I. Expression of aryl hydrocarbon receptor in the C57BL/6N mouse embryo

  1995cited by this paper
• Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor

  1995cited by this paper
• The aryl hydrocarbon receptor complex.

  1995influential reference
• Structure elucidation of two tryptophan-derived, high affinity Ah receptor ligands.

  1995cited by this paper
• Reaction of phenylglyoxal with arginine groups in D-amino-acid oxidase from Rhodotorula gracilis.

  1994cited by this paper
• D-Amino acids in chronic renal failure and the effects of dialysis and urinary losses

  1994cited by this paper
• D-amino acid levels in human physiological fluids.

  1993cited by this paper
• Free D-serine, D-aspartate and D-alanine in central nervous system and serum in mutant mice lacking D-amino acid oxidase.

  1993cited by this paper
• Response of human CYP1-luciferase plasmids to 2,3,7,8-tetrachlorodibenzo-p-dioxin and polycyclic aromatic hydrocarbons.

  1993cited by this paper
• The presence of free D‐serine in rat brain

  1992cited by this paper
• Determination of free amino acid enantiomers in rat brain and serum by high-performance liquid chromatography after derivatization with N-tert.-butyloxycarbonyl-L-cysteine and o-phthaldialdehyde.

  1992cited by this paper
• Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo: comparisons with 2,3,7,8-tetrachlorodibenzo-p-dioxin.

  1991influential reference
• Involvement of D-amino acid oxidase in elimination of free D-amino acids in mice.

  1989cited by this paper
• Certain photooxidized derivatives of tryptophan bind with very high affinity to the Ah receptor and are likely to be endogenous signal substances.

  1987cited by this paper
• Free D-amino acids in human plasma in relation to senescence and renal diseases.

  1987cited by this paper
• The presence of free D-aspartic acid in rodents and man.

  1986cited by this paper
• Racemization kinetics of amino acid residues in alkali-treated soybean protein

  1985cited by this paper
• Studies on the mechanism of action of halogenated aromatic hydrocarbons.

  1985cited by this paper
• Thermodynamic control of D-amino acid oxidase by benzoate binding.

  1985cited by this paper
• Effect of dietary indole-3-carbinol on intestinal and hepatic monooxygenase, glutathione S-transferase and epoxide hydrolase activities in the rat.

  1984cited by this paper
• The utilization and safety of isomeric sulfur-containing amino acids in mice.

  1984cited by this paper
• The nutritive value and safety of D-phenylalanine and D-tyrosine in mice.

  1984cited by this paper
• Mouse mutant deficient in D-amino acid oxidase activity.

  1983cited by this paper
• Intraspecies and interspecies variations in the substrate specificity of D-amino acid oxidase.

  1982cited by this paper
• PCB isomers and congeners: induction of aryl hydrocarbon hydroxylase and ethoxyresorufin O-deethylase enzyme activities in rat hepatoma cells.

  1982cited by this paper
• Racemization of amino acid residues in proteins and poly (L-amino acids) during roasting.

  1975cited by this paper
• Studies on the metabolism of D- and L-isomers of 3,4-dihydroxyphenylalanine (DOPA). VI. Metabolism of D-DOPA in rat kidney.

  1974cited by this paper
• Physiology of the D-amino acids.

  1953cited by this paper

• The aryl hydrocarbon receptor: structure, signaling, physiology and pathology

  2026cites this paper
• Biological function of d-tryptophan: a bibliometric analysis and review

  2025cites this paper
• Convenient alternative synthesis of the Malassezia-derived virulence factor malassezione and related compounds

  2025cites this paper
• The aryl hydrocarbon receptor: a rehabilitated target for therapeutic immune modulation

  2025cites this paper
• Discrete interplay of gut microbiota L-tryptophan metabolites in host biology and disease

  2023cites this paper
• Ligands and agonists of the aryl hydrocarbon receptor AhR: Facts and Myths.

  2023cites this paper
• Targeting the Aryl Hydrocarbon Receptor with Microbial Metabolite Mimics Alleviates Experimental Colitis in Mice.

  2022cites this paper
• Tryptophan Metabolism ‘Hub’ Gene Expression Associates with Increased Inflammation and Severe Disease Outcomes in COVID-19 Infection and Inflammatory Bowel Disease

  2022cites this paper
• The aryl hydrocarbon receptor as a model PAS sensor

  2021cites this paper
• Indole scaffolds as a promising class of the aryl hydrocarbon receptor ligands.

  2021cites this paper
• Complexities of the chemogenetic toolkit: Differential mDAAO activation by d-amino substrates and subcellular targeting.

  2021cites this paper
• The Ah Receptor: Adaptive Metabolism, Ligand Diversity, and the Xenokine Model

  2020cites this paper
• Conditional deletion of Ahr alters gene expression profiles in hematopoietic stem cells

  2018cites this paper
• 8.09 – The Aryl Hydrocarbon Receptor as a Regulator of Barrier Physiology

  2018cites this paper
• Towards an Integrative Understanding of tRNA Aminoacylation–Diet–Host–Gut Microbiome Interactions in Neurodegeneration

  2018cites this paper
• Aryl Hydrocarbon Receptor: An Environmental Sensor in Control of Allergy Outcomes

  2017cites this paper
• Trypanosoma brucei metabolite indolepyruvate decreases HIF-1α and glycolysis in macrophages as a mechanism of innate immune evasion

  2016cites this paper
• Role of d‐amino acid oxidase in the production of kynurenine pathway metabolites from d‐tryptophan in mice

  2016cites this paper
• The urinary ratio of 3-hydroxykynurenine/3-hydroxyanthranilic acid is an index to predicting the adverse effects of D-tryptophan in rats.

  2014cites this paper
• The human Ah receptor: hints from dioxin toxicities to deregulated target genes and physiological functions

  2013cites this paper
• The aryl hydrocarbon receptor: a molecular pathway for the environmental control of the immune response

  2013cites this paper
• Expression of the aryl hydrocarbon receptor is not required for the proliferation, migration, invasion, or estrogen‐dependent tumorigenesis of MCF‐7 breast cancer cells

  2013cites this paper
• Regulation of central nervous system autoimmunity by the aryl hydrocarbon receptor

  2013cites this paper
• AUTOIMMUNITY BY THE ARYL HYDROCARBON RECEPTOR

  2013cites this paper
• The aryl hydrocarbon receptor regulates gut immunity through modulation of innate lymphoid cells.

  2012cites this paper
• Alterations in extracellular tryptophan and dopamine concentrations in rat striatum following peripheral administration of D- and L-tryptophan: an in vivo microdialysis study.

  2012cites this paper
• d-Amino acids and cross-linked amino acids as food contaminants

  2012cites this paper
• History of Research on the AHR

  2011cites this paper
• Dioxin toxicity, aryl hydrocarbon receptor signaling, and apoptosis—Persistent pollutants affect programmed cell death

  2011cites this paper
• Influence of light on aryl hydrocarbon receptor signaling and consequences in drug metabolism, physiology and disease

  2011cites this paper
• Fluorescence determination of D- and L-tryptophan concentrations in rat plasma following administration of tryptophan enantiomers using HPLC with pre-column derivatization.

  2011cites this paper
• Nutritional and medicinal aspects of d-amino acids

  2011cites this paper
• This information is current as Regulatory T Cells Aryl Hydrocarbon Receptor Can Generate An Interaction between Kynurenine and the

  2010cites this paper
• Potent 3-methylindole-mediated DNA damage, cytochrome p450 induction, and mutagenicity in human lung

  2010cites this paper
• The aryl hydrocarbon receptor: regulation of hematopoiesis and involvement in the progression of blood diseases.

  2010cites this paper
• An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells

  2010cites this paper
• Dioxins, the aryl hydrocarbon receptor and the central regulation of energy balance.

  2010cites this paper
• Induction of cytochrome P450 1 genes and stress response genes in developing zebrafish exposed to ultraviolet radiation.

  2010cites this paper
• 3-Methylindole metabolites induce lung CYP1A1 and CYP2F1 enzymes by AhR and non-AhR mechanisms, respectively.

  2010cites this paper
• Structural identification of Diindole agonists of the aryl hydrocarbon receptor derived from degradation of indole-3-pyruvic acid.

  2009cites this paper