Effect of Deletion of Ghrelin‐O‐Acyltransferase on the Pulsatile Release of Growth Hormone in Mice

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Journal of neuroendocrinology

• Publication date

  2015-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/jne.12327PMID 26442444
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• [The regulation of growth hormone secretion].

  2018cited by this paper
• Somatostatin is essential for the sexual dimorphism of GH secretion, corticosteroid-binding globulin production, and corticosterone levels in mice.

  2015cited by this paper
• Nutrient Sensing Overrides Somatostatin and Growth Hormone‐Releasing Hormone to Control Pulsatile Growth Hormone Release

  2015cited by this paper
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  2015cited by this paper
• The suppression of ghrelin signaling mitigates age-associated thermogenic impairment

  2014cited by this paper
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  2014cited by this paper
• Age-dependent decline in acyl-ghrelin concentrations and reduced association of acyl-ghrelin and growth hormone in healthy older adults.

  2014cited by this paper
• Integrating Systems Biology Markup Language (SBML) with NEURON

  2014cited by this paper
• An early reduction in GH peak amplitude in preproghrelin-deficient male mice has a minor impact on linear growth.

  2014cited by this paper
• Ghrelin accelerates synapse formation and activity development in cultured cortical networks

  2014cited by this paper
• Increased adiposity and insulin correlates with the progressive suppression of pulsatile GH secretion during weight gain.

  2013cited by this paper
• Hypothalamic Distribution of Somatostatin mRNA Expressing Neurones Relative to Pubertal and Adult Changes in Pulsatile Growth Hormone Secretion in Mice

  2013cited by this paper
• Ablation of Ghrelin O-Acyltransferase Does Not Improve Glucose Intolerance or Body Adiposity in Mice on a Leptin-Deficient ob/ob Background

  2013cited by this paper
• Acylated and unacylated ghrelin impair skeletal muscle atrophy in mice.

  2013cited by this paper
• Hormonal regulation of Cyp4a isoforms in mouse liver and kidney

  2013cited by this paper
• The decline in pulsatile GH secretion throughout early adulthood in mice is exacerbated by dietary-induced weight gain.

  2012cited by this paper
• GH does not modulate the early fasting-induced release of free fatty acids in mice.

  2012cited by this paper
• The effect of growth hormone deficiency on size-corrected bone mineral measures in pre-pubertal children

  2012cited by this paper
• Ablation of ghrelin receptor reduces adiposity and improves insulin sensitivity during aging by regulating fat metabolism in white and brown adipose tissues

  2011cited by this paper
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  2011cited by this paper
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  2010cited by this paper
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  2010cited by this paper
• Development of hypothalamic neural networks controlling appetite.

  2010cited by this paper
• Ghrelin O-acyltransferase (GOAT) is essential for growth hormone-mediated survival of calorie-restricted mice

  2010cited by this paper
• Ghrelin alters postnatal endocrine secretion and behavior in mouse offspring.

  2009cited by this paper
• Relative effects of estrogen, age, and visceral fat on pulsatile growth hormone secretion in healthy women.

  2009cited by this paper
• Ghrelin octanoylation mediated by an orphan lipid transferase

  2008cited by this paper
• Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone.

  2008cited by this paper
• Growth hormone (GH)–releasing hormone and GH secretagogues in normal aging: Fountain of Youth or Pool of Tantalus?

  2008cited by this paper
• Evidence for acyl-ghrelin modulation of growth hormone release in the fed state.

  2008cited by this paper
• Active and total ghrelin concentrations increase in breast milk during lactation

  2007cited by this paper
• Loss of sexually dimorphic liver gene expression upon hepatocyte-specific deletion of Stat5a-Stat5b locus.

  2007cited by this paper
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  2007cited by this paper
• Maternal ghrelin plays an important role in rat fetal development during pregnancy.

  2006cited by this paper
• Sex-dependent liver gene expression is extensive and largely dependent upon signal transducer and activator of transcription 5b (STAT5b): STAT5b-dependent activation of male genes and repression of female genes revealed by microarray analysis.

  2006cited by this paper
• Ghrelin is present in human colostrum, transitional and mature milk.

  2006cited by this paper
• Codependence of growth hormone-responsive, sexually dimorphic hepatic gene expression on signal transducer and activator of transcription 5b and hepatic nuclear factor 4alpha.

  2006cited by this paper
• Ghrelin and cholecystokinin in term and preterm human breast milk

  2006cited by this paper
• Endogenous ghrelin regulates episodic growth hormone (GH) secretion by amplifying GH Pulse amplitude: evidence from antagonism of the GH secretagogue-R1a receptor.

  2005cited by this paper
• Transgenic mice overexpressing des-acyl ghrelin show small phenotype.

  2005cited by this paper
• Absence of ghrelin protects against early-onset obesity.

  2005cited by this paper
• Endogenous circulating ghrelin does not mediate growth hormone rhythmicity or response to fasting.

  2005cited by this paper
• Nocturnal ghrelin pulsatility and response to growth hormone secretagogues in healthy men.

  2004cited by this paper
• Comparing adiposity profiles in three mouse models with altered GH signaling.

  2004cited by this paper
• Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor.

  2004cited by this paper
• Cellular distribution and regulation of ghrelin messenger ribonucleic acid in the rat pituitary gland.

  2003cited by this paper
• Human GH pulsatility: An ensemble property regulated by age and gender

  2003cited by this paper
• Role of Ghrelin in the Control of Growth Hormone Secretion in Prepubertal Rats: Interactions with Excitatory Amino Acids

  2003cited by this paper
• Deletion of Ghrelin Impairs neither Growth nor Appetite

  2003cited by this paper
• Ghrelin main action on the regulation of growth hormone release is exerted at hypothalamic level.

  2003cited by this paper
• Ultradian rhythmicity of ghrelin secretion in relation with GH, feeding behavior, and sleep-wake patterns in rats.

  2002cited by this paper
• Regulation of the expression of two female-predominant CYP3A mRNAs (CYP3A41 and CYP3A44) in mouse liver by sex and growth hormones.

  2002cited by this paper
• The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats.

  2002cited by this paper
• Roles of growth hormone and insulin-like growth factor 1 in mouse postnatal growth.

  2001cited by this paper
• Ghrelin, an endogenous growth hormone secretagogue, is a novel orexigenic peptide that antagonizes leptin action through the activation of hypothalamic neuropeptide Y/Y1 receptor pathway.

  2001cited by this paper
• Ghrelin causes hyperphagia and obesity in rats.

  2001cited by this paper
• A low dose of ghrelin stimulates growth hormone (GH) release synergistically with GH-releasing hormone in humans.

  2001cited by this paper
• Abdominal visceral fat and fasting insulin are important predictors of 24-hour GH release independent of age, gender, and other physiological factors.

  2001cited by this paper
• Impact of pulsatility on the ensemble orderliness (approximate entropy) of neurohormone secretion.

  2001cited by this paper
• Somatostatin is required for masculinization of growth hormone-regulated hepatic gene expression but not of somatic growth.

  2001cited by this paper
• A role for ghrelin in the central regulation of feeding

  2001cited by this paper
• Ghrelin enhances appetite and increases food intake in humans.

  2001cited by this paper
• Insulin-Like Growth Factor I

  2000cited by this paper
• The relative importance of endocrine versus autocrine/paracrine insulin-like growth factor-I in the regulation of body growth

  2000cited by this paper
• Ghrelin elicits a marked stimulatory effect on GH secretion in freely-moving rats.

  2000cited by this paper
• Ghrelin strongly stimulates growth hormone release in humans.

  2000cited by this paper
• Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice.

  1999cited by this paper
• Ghrelin is a growth-hormone-releasing acylated peptide from stomach

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  1998cited by this paper
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  1990cited by this paper
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• Growth hormone stimulates c-fos gene expression by means of protein kinase C without increasing inositol lipid turnover.

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• Pulsatile intravenous growth hormone (GH) infusion to hypophysectomized rats increases insulin-like growth factor I messenger ribonucleic acid in skeletal tissues more effectively than continuous GH infusion.

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  1987cited by this paper
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• Negative feedback loops and hormonal factors that regulate growth hormone secretion.

  2025cites this paper
• Ghrelin as a treatment for amyotrophic lateral sclerosis

  2021cites this paper
• Ghrelin Gene Deletion Alters Pulsatile Growth Hormone Secretion in Adult Female Mice

  2021cites this paper
• A skeleton in the cupboard in ghrelin research: Where are the skinny dwarfs?

  2021cites this paper
• Effect of Growth Hormone Secretagogue Receptor Deletion on Growth, Pulsatile Growth Hormone Secretion, and Meal Pattern in Male and Female Mice

  2021cites this paper
• Tyrosine Hydroxylase Neurons Regulate Growth Hormone Secretion via Short-Loop Negative Feedback

  2020cites this paper
• Pregnancy, but not dietary octanoic acid supplementation, stimulates the ghrelin-pituitary growth.

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• An overview of ghrelin O-acyltransferase inhibitors: a literature and patent review for 2010-2019

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• The Mouse Microbiome Is Required for Sex-Specific Diurnal Rhythms of Gene Expression and Metabolism

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• Acylated Ghrelin Supports the Ovarian Transcriptome and Follicles in the Mouse: Implications for Fertility

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• Loss of HCN2 leads to delayed gastrointestinal motility and reduced energy intake in mice

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• Aromatized Estrogens Amplify Nocturnal Growth Hormone Secretion in Testosterone-Replaced Older Hypogonadal Men

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  2017cites this paper
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  2016cites this paper
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• Normal Physiology of ACTH and GH Release in the Hypothalamus and Anterior Pituitary in Man

  2014cites this paper