Discovery of Potential Diagnostic and Vaccine Antigens in Herpes Simplex Virus 1 and 2 by Proteome-Wide Antibody Profiling

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Journal of Virology

• Publication date

  2012-02-08

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/JVI.05194-11PMID 22318154PMCID PMC3318641
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Measurement of antibody responses to Modified Vaccinia virus Ankara (MVA) and Dryvax(®) using proteome microarrays and development of recombinant protein ELISAs.

  2012cited by this paper
• Identification of Potential Serodiagnostic and Subunit Vaccine Antigens by Antibody Profiling of Toxoplasmosis Cases in Turkey*

  2011cited by this paper
• Herpes simplex virus type 2 seropositivity and relationship status among U.S. adults age 20 to 49: a population-based analysis

  2010cited by this paper
• The glycoproteins C and G are equivalent target antigens for the determination of herpes simplex virus type 1-specific antibodies.

  2010influential reference
• High-throughput profiling of the humoral immune responses against thirteen human papillomavirus types by proteome microarrays.

  2010cited by this paper
• Uncovering the interplay between CD8, CD4 and antibody responses to complex pathogens.

  2010cited by this paper
• A prospective analysis of the Ab response to Plasmodium falciparum before and after a malaria season by protein microarray

  2010cited by this paper
• Seroprevalence of herpes simplex virus type 2 among persons aged 14-49 years--United States, 2005-2008.

  2010cited by this paper
• Human antibodies to herpes simplex virus type 1 glycoprotein C are neutralizing and target the heparan sulfate-binding domain.

  2010cited by this paper
• Dynamic antibody responses to the Mycobacterium tuberculosis proteome

  2010cited by this paper
• New concepts in herpes simplex virus vaccine development: notes from the battlefield

  2009cited by this paper
• A Burkholderia pseudomallei protein microarray reveals serodiagnostic and cross-reactive antigens

  2009cited by this paper
• HLA-A*0201-Restricted CD8+ Cytotoxic T Lymphocyte Epitopes Identified from Herpes Simplex Virus Glycoprotein D1

  2008cited by this paper
• An Extremely Diverse CD4 Response to Vaccinia Virus in Humans Is Revealed by Proteome-Wide T-Cell Profiling

  2008cited by this paper
• Asymptomatic Human CD4+ Cytotoxic T-Cell Epitopes Identified from Herpes Simplex Virus Glycoprotein B

  2008influential reference
• From protein microarrays to diagnostic antigen discovery: a study of the pathogen Francisella tularensis

  2007cited by this paper
• Vaccinia Virus-Specific CD4+ T Cell Responses Target a Set of Antigens Largely Distinct from Those Targeted by CD8+ T Cell Responses1

  2007cited by this paper
• Production of recombinant gG-1 protein of herpes simplex virus type 1 in a prokaryotic system in order to develop a type-specific enzyme-linked immunosorbent assay kit.

  2007cited by this paper
• Diversity of the CD8+ T-Cell Response to Herpes Simplex Virus Type 2 Proteins among Persons with Genital Herpes

  2006cited by this paper
• Trends in herpes simplex virus type 1 and type 2 seroprevalence in the United States.

  2006cited by this paper
• Herpes simplex virus 2 infection increases HIV acquisition in men and women: systematic review and meta-analysis of longitudinal studies

  2006cited by this paper
• Profiling the humoral immune response to infection by using proteome microarrays: high-throughput vaccine and diagnostic antigen discovery.

  2005cited by this paper
• Clinical trials of prophylactic and therapeutic herpes simplex virus vaccines.

  2004cited by this paper
• Interplay between Alpha/Beta and Gamma Interferons with B, T, and Natural Killer Cells in the Defense against Herpes Simplex Virus Type 1

  2004cited by this paper
• National Seroprevalence and Trends in Herpes Simplex Virus Type 1 in the United States, 1976–1994

  2004cited by this paper
• Immunodominance among herpes simplex virus-specific CD8 T cells expressing a tissue-specific homing receptor

  2003cited by this paper
• Recent Progress in Herpes Simplex Virus Immunobiology and Vaccine Research

  2003cited by this paper
• T Cell Immunity to Herpes Simplex Viruses in Seronegative Subjects: Silent Infection or Acquired Immunity?1

  2003cited by this paper
• Glycoprotein D-adjuvant vaccine to prevent genital herpes.

  2003cited by this paper
• Effect of serologic status and cesarean delivery on transmission rates of herpes simplex virus from mother to infant.

  2003cited by this paper
• Identification of Novel Immunodominant CD4+ Th1-Type T-Cell Peptide Epitopes from Herpes Simplex Virus Glycoprotein D That Confer Protective Immunity

  2003influential reference
• Time Course of Seroconversion by HerpeSelect ELISA After Acquisition of Genital Herpes Simplex Virus Type 1 (HSV-1) or HSV-2

  2003cited by this paper
• Glycoprotein-D-adjuvant vaccine to prevent genital herpes.

  2002cited by this paper
• Risk Factors for

  2002cited by this paper
• A variance-stabilizing transformation for gene-expression microarray data

  2002cited by this paper
• Variance stabilization applied to microarray data calibration and to the quantification of differential expression

  2002cited by this paper
• A Bayesian framework for the analysis of microarray expression data: regularized t -test and statistical inferences of gene changes

  2001cited by this paper
• Sorting out the new HSV type specific antibody tests

  2001cited by this paper
• Vaccine-Induced Serum Immunoglobin Contributes to Protection from Herpes Simplex Virus Type 2 Genital Infection in the Presence of Immune T Cells

  2001cited by this paper
• CD8 CTL from Genital Herpes Simplex Lesions: Recognition of Viral Tegument and Immediate Early Proteins and Lysis of Infected Cutaneous Cells1

  2001influential reference
• Improved Statistical Inference from DNA Microarray Data Using Analysis of Variance and A Bayesian Statistical Framework

  2001cited by this paper
• Dual role of B cells in mediating innate and acquired immunity to herpes simplex virus infections.

  2000cited by this paper
• Adhesion Defects of Antibody-Mediated Target Cell Binding of Neonatal Natural Killer Cells

  1999cited by this paper
• Ability of a Rapid Serology Test To Detect Seroconversion to Herpes Simplex Virus Type 2 Glycoprotein G Soon after Infection

  1999cited by this paper
• Recombinant glycoprotein vaccine for the prevention of genital HSV-2 infection: two randomized controlled trials. Chiron HSV Vaccine Study Group.

  1999cited by this paper
• Identification of type-specific domains within glycoprotein G of herpes simplex virus type 2 (HSV-2) recognized by the majority of patients infected with HSV-2, but not by those infected with HSV-1.

  1999cited by this paper
• The Genome Sequence of Herpes Simplex Virus Type 2

  1998cited by this paper
• Herpes simplex virus type 1 glycoproteins gB, gC and gD are major targets for CD4 T-lymphocyte cytotoxicity in HLA-DR expressing human epidermal keratinocytes.

  1998influential reference
• Herpes simplex virus type 2 in the United States, 1976 to 1994.

  1998cited by this paper
• Herpes Simplex Virus Type 2 in the United States, 1976 to 1994

  1997cited by this paper
• The acquisition of herpes simplex virus during pregnancy.

  1997cited by this paper
• Frequent genital herpes simplex virus 2 shedding in immunocompetent women. Effect of acyclovir treatment.

  1997cited by this paper
• Rapid detection and typing of herpes simplex virus DNA in clinical specimens by the hybrid capture II signal amplification probe test

  1997cited by this paper
• Herpes simplex virus protein targets for CD4 and CD8 lymphocyte cytotoxicity in cultured epidermal keratinocytes treated with interferon-gamma.

  1996influential reference
• T cell recognition and cytokine production elicited by common and type-specific glycoproteins of herpes simplex virus type 1 and type 2.

  1996cited by this paper
• Herpes Simplex Virus Protein Targets for CD4 and CD8 Lymphocyte Cytotoxicity in Cultured Epidermal Keratinocytes Treated with Interferon-γ

  1996cited by this paper
• Immunization with DNA vaccines encoding glycoprotein D or glycoprotein B, alone or in combination, induces protective immunity in animal models of herpes simplex virus-2 disease.

  1996cited by this paper
• A recombinant glycoprotein vaccine for herpes simplex virus type 2: safety and immunogenicity [corrected].

  1995cited by this paper
• A Recombinant Glycoprotein Vaccine for Herpes Simplex Type 2: Safety and Efficacy

  1995cited by this paper
• Controlling the false discovery rate: a practical and powerful approach to multiple testing

  1995cited by this paper
• Escherichia coli expressed herpes simplex virus gG1 and gG2 proteins in ELISA and immunoblotting assays.

  1995cited by this paper
• Effects of the passive transfer of anti-gB antibodies in a rabbit model of HSV-1-induced keratitis.

  1995cited by this paper
• Antigenic specificities of human CD4+ T-cell clones recovered from recurrent genital herpes simplex virus type 2 lesions

  1994cited by this paper
• Direct recovery of herpes simplex virus (HSV)-specific T lymphocyte clones from recurrent genital HSV-2 lesions.

  1994cited by this paper
• Role of NK cells in immunomodulator-mediated resistance to herpesvirus infection.

  1993cited by this paper
• A cosmid-based system for constructing mutants of herpes simplex virus type 1.

  1993cited by this paper
• Risk Factors for the Sexual Transmission of Genital Herpes

  1992cited by this paper
• Genetic analysis of type-specific antigenic determinants of herpes simplex virus glycoprotein C

  1992cited by this paper
• Herpes simplex virus type 1 Fc receptor protects infected cells from antibody-dependent cellular cytotoxicity

  1991cited by this paper
• Protection from herpes simplex virus type 1 lethal and latent infections by secreted recombinant glycoprotein B constitutively expressed in human cells with a BK virus episomal vector

  1990cited by this paper
• Mucosal and systemic antiviral antibodies in mice inoculated intravaginally with herpes simplex virus type 2.

  1990cited by this paper
• Herpes Simplex Virus Type 1: A Cause of the Acute Retinal Necrosis Syndrome+

  1989cited by this paper
• A major neutralizing domain maps within the carboxyl-terminal half of the cleaved cytomegalovirus B glycoprotein.

  1989cited by this paper
• Protection of mice against lethal challenge with herpes simplex virus by vaccination with an adenovirus vector expressing HSV glycoprotein B.

  1989cited by this paper
• Immunization with a vaccinia virus recombinant expressing herpes simplex virus type 1 glycoprotein D: long-term protection and effect of revaccination

  1988cited by this paper
• Passive transfer of anti-HSV-1 IgG protects against stromal keratitis in mice.

  1988cited by this paper
• The immunoglobulin response to individual HSV-1 viral polypeptides: kinetics of the response during primary and secondary experimental infection with herpes simplex virus.

  1988cited by this paper
• Comparison of Western blot (immunoblot) and glycoprotein G-specific immunodot enzyme assay for detecting antibodies to herpes simplex virus types 1 and 2 in human sera

  1988influential reference
• Transmission of genital herpes in couples with one symptomatic and one asymptomatic partner: a prospective study.

  1988cited by this paper
• The complete DNA sequence of the long unique region in the genome of herpes simplex virus type 1.

  1988cited by this paper
• Use of densitometric analysis for interpreting HSV serologies based on Western blot.

  1987cited by this paper
• DNA sequence and genetic content of the HindIII l region in the short unique component of the herpes simplex virus type 2 genome: identification of the gene encoding glycoprotein G, and evolutionary comparisons.

  1987cited by this paper
• Expression of herpes simplex virus 1 glycoprotein B by a recombinant vaccinia virus and protection of mice against lethal herpes simplex virus 1 infection.

  1987cited by this paper
• IgG-mediated viral clearance in experimental infection with herpes simplex virus type 1: role for neutralization and Fc-dependent functions but not C' cytolysis and C5 chemotaxis.

  1985cited by this paper
• Synthetic glycoprotein D-related peptides protect mice against herpes simplex virus challenge

  1985cited by this paper
• Characterization of the 92,000-dalton glycoprotein induced by herpes simplex virus type 2

  1984cited by this paper
• DNA Sequence Analysis of the Type-Common Glycoprotein-D Genes of Herpes Simplex Virus Types 1 and 2

  1984cited by this paper
• Mechanism of Antibody‐Mediated Protection against Herpes Simplex Virus Infection in Athymic Nude Mice: Requirement of Fc Portion of Antibody

  1982cited by this paper
• Bioinformatics Original Paper Identification of Humoral Immune Responses in Protein Microarrays Using Dna Microarray Data Analysis Techniques

  year unknowncited by this paper

• Immunoproteomics: The Evolution from Classical Methods to Emerging Techniques.

  2026cites this paper
• Role of mucosal chemokines in the development of tissue-resident CD4+ and CD8+ TRM cells to fend off herpes simplex infections.

  2026cites this paper
• Varicella zoster virus and the central nervous system.

  2026cites this paper
• An African swine fever virus-specific antibody reactome reveals antigens as potential candidates for vaccine development

  2025cites this paper
• The immunobiology of corneal HSV-1 infection and herpetic stromal keratitis

  2024cites this paper
• Structures of Epstein-Barr virus and Kaposi’s sarcoma-associated herpesvirus virions reveal species-specific tegument and envelope features

  2024cites this paper
• Therapeutic prime/pull vaccination of HSV-2-infected guinea pigs with the ribonucleotide reductase 2 (RR2) protein and CXCL11 chemokine boosts antiviral local tissue-resident and effector memory CD4+ and CD8+ T cells and protects against recurrent genital herpes

  2024cites this paper
• High Frequencies of Antiviral Effector Memory TEM Cells and Memory B Cells Mobilized into Herpes Infected Vaginal Mucosa Associated With Protection Against Genital Herpes

  2023cites this paper
• Immunization of Mice with Virus-Like Vesicles of Kaposi Sarcoma-Associated Herpesvirus Reveals a Role for Antibodies Targeting ORF4 in Activating Complement-Mediated Neutralization

  2023cites this paper
• Mucosal CCL28 Chemokine Improves Protection against Genital Herpes through Mobilization of Antiviral Effector Memory CCR10+CD44+ CD62L-CD8+ T Cells and Memory CCR10+B220+CD27+ B Cells into the Infected Vaginal Mucosa.

  2023cites this paper
• Association between human herpes simplex virus and periodontitis: results from the continuous National Health and Nutrition Examination Survey 2009–2014

  2023cites this paper
• Estimation of Seroprevalence of Anti-Herpes Simplex Virus Type-1 IgG Among Healthy Blood Donors in Sakaka City, Aljouf, Saudi Arabia

  2023cites this paper
• Therapeutic Prime/Pull Vaccination of HSV-2 Infected Guinea Pigs with the Ribonucleotide Reductase 2 (RR2) Protein and CXCL11 Chemokine Boosts Antiviral Local Tissue-Resident and Effector Memory CD4+ and CD8+ T Cells and Protects Against Recurrent Genital Herpes

  2023cites this paper
• A Prime/Pull RR2/CXCL11 Therapeutic Vaccine that Bolsters the Number and Function of Dorsal Root Ganglia Tissue-Resident HSV-Specific CD8+ TRM Cells Protects Latently Infected Guinea Pigs from Recurrent Genital Herpes

  2022cites this paper
• Role of Multiomics Data to Understand Host–Pathogen Interactions in COVID-19 Pathogenesis

  2021cites this paper
• Serum and Cervicovaginal Fluid Antibody Profiling in Herpes Simplex Virus (HSV) Seronegative Recipients of the HSV529 Vaccine.

  2021cites this paper
• Serum and Cervicovaginal Fluid Antibody Profiling in Herpes Simplex Virus–Seronegative Recipients of the HSV529 Vaccine

  2021cites this paper
• Human Epitopes Identified from Herpes Simplex Virus Tegument Protein VP11/12 (UL46) Recall Multifunctional Effector Memory CD4+ TEM Cells in Asymptomatic Individuals and Protect from Ocular Herpes Infection and Disease in “Humanized” HLA-DR Transgenic Mice

  2020cites this paper
• Risk Factors and Seroepidemiologic Analyses of Herpes Simplex Virus Types 1 and 2 in Asymptomatic Persons in a Tertiary Institution in South Eastern Nigeria Obi International Journal of Virology & Infectious Diseases

  2020cites this paper
• Cytotoxic and Antiviral Activities of Vacuum Liquid Chromatography Fractions of Azadirachta Indica

  2020cites this paper
• Developments and Applications of Functional Protein Microarrays*

  2020influential citation
• Therapeutic Mucosal Vaccination of Herpes Simplex Virus 2-Infected Guinea Pigs with Ribonucleotide Reductase 2 (RR2) Protein Boosts Antiviral Neutralizing Antibodies and Local Tissue-Resident CD4+ and CD8+ TRM Cells Associated with Protection against Recurrent Genital Herpes

  2019cites this paper
• Blockade of PD-1 and LAG-3 Immune Checkpoints Combined with Vaccination Restores the Function of Antiviral Tissue-Resident CD8+ TRM Cells and Reduces Ocular Herpes Simplex Infection and Disease in HLA Transgenic Rabbits

  2019cites this paper
• Immunoproteomics Methods and Techniques.

  2019cites this paper
• Herpes simplex virus type 1 and Alzheimer’s disease: link and potential impact on treatment

  2019cites this paper
• A trivalent gC2/gD2/gE2 vaccine for herpes simplex virus generates antibody responses that block immune evasion domains on gC2 better than natural infection.

  2019cites this paper
• Rapid immunodiagnostics of multiple viral infections in an acoustic microstreaming device with serum and saliva samples.

  2019cites this paper
• A Novel Shigella Proteome Microarray Discriminates Targets of Human Antibody Reactivity following Oral Vaccination and Experimental Challenge

  2018cites this paper
• CXCL17 Chemokine–Dependent Mobilization of CXCR8+CD8+ Effector Memory and Tissue-Resident Memory T Cells in the Vaginal Mucosa Is Associated with Protection against Genital Herpes

  2018cites this paper
• Laser Adjuvant-Assisted Peptide Vaccine Promotes Skin Mobilization of Dendritic Cells and Enhances Protective CD8+ TEM and TRM Cell Responses against Herpesvirus Infection and Disease

  2018cites this paper
• Phenotypic and Functional Signatures of Herpes Simplex Virus–Specific Effector Memory CD73+CD45RAhighCCR7lowCD8+ TEMRA and CD73+CD45RAlowCCR7lowCD8+ TEM Cells Are Associated with Asymptomatic Ocular Herpes

  2018cites this paper
• Blockade of LAG-3 Immune Checkpoint Combined With Therapeutic Vaccination Restore the Function of Tissue-Resident Anti-viral CD8+ T Cells and Protect Against Recurrent Ocular Herpes Simplex Infection and Disease

  2018cites this paper
• CXCL17 Chemokine-Dependent Mobilization of Memory CXCR8 + CD8 + T EM and T RM Cells in the Vaginal Mucosa is Associated with Protection Against Genital Herpes

  2018cites this paper
• Characterization of rubella-specific humoral immunity following two doses of MMR vaccine using proteome microarray technology

  2017cites this paper
• Identification of Novel Serodiagnostic Signatures of Typhoid Fever Using a Salmonella Proteome Array

  2017cites this paper
• Human Asymptomatic Epitopes Identified from the Herpes Simplex Virus Tegument Protein VP13/14 (UL47) Preferentially Recall Polyfunctional Effector Memory CD44high CD62Llow CD8+ TEM Cells and Protect Humanized HLA-A*02:01 Transgenic Mice against Ocular Herpesvirus Infection

  2016cites this paper
• Applications in high-content functional protein microarrays.

  2016cites this paper
• A systems biology approach for diagnostic and vaccine antigen discovery in tropical infectious diseases

  2015cites this paper
• HLA-A02:01–Restricted Epitopes Identified from the Herpes Simplex Virus Tegument Protein VP11/12 Preferentially Recall Polyfunctional Effector Memory CD8+ T Cells from Seropositive Asymptomatic Individuals and Protect Humanized HLA-A*02:01 Transgenic Mice against Ocular Herpes

  2015cites this paper
• Profiling of Measles-Specific Humoral Immunity in Individuals Following Two Doses of MMR Vaccine Using Proteome Microarrays

  2015cites this paper
• Identification of immuno-reactive capsid proteins of malignant catarrhal fever viruses.

  2014cites this paper
• The Challenges and Opportunities for Development of a T-Cell Epitope-Based Herpes Simplex Vaccine

  2014cites this paper
• Asymptomatic memory CD8+ T cells

  2014cites this paper
• Functional Characterization of Ocular-Derived Human Alphaherpesvirus Cross-Reactive CD4 T Cells

  2014cites this paper
• The challenges and opportunities for the development of a T-cell epitope-based herpes simplex vaccine.

  2014cites this paper
• Cross-Reactive CD4 T Cells Ocular-Derived Human Alphaherpesvirus Functional Characterization of

  2014cites this paper
• Current status and prospects for development of an HSV vaccine.

  2014cites this paper
• Clinical use of anti-TNF therapy and increased risk of infections

  2013cites this paper
• Malaria vaccines: high-throughput tools for antigens discovery with potential for their development

  2013cites this paper
• Immunoproteomics: current technology and applications.

  2013cites this paper
• Development of Recombinant Antigen Array for Simultaneous Detection of Viral Antibodies

  2013cites this paper
• Immune profiling with a Salmonella Typhi antigen microarray identifies new diagnostic biomarkers of human typhoid

  2013cites this paper
• Review Point Malaria vaccines: high-throughput tools for antigen discovery with development potential Vacunas contra la malaria: estrategias de alto rendimiento para el descubrimiento de antígenos con potencial para su desarrollo

  2013cites this paper
• Future of an "Asymptomatic" T-cell Epitope-Based Therapeutic Herpes Simplex Vaccine.

  2012cites this paper
• Immunodominant “Asymptomatic” Herpes Simplex Virus 1 and 2 Protein Antigens Identified by Probing Whole-ORFome Microarrays with Serum Antibodies from Seropositive Asymptomatic versus Symptomatic Individuals

  2012cites this paper
• Characterization of the Viral O-Glycopeptidome: a Novel Tool of Relevance for Vaccine Design and Serodiagnosis

  2012cites this paper
• Malaria vaccines : high-throughput tools for antigen discovery with development potential

  year unknowncites this paper