Human umbilical cord‐derived mesenchymal stem cells conditioned medium attenuate interstitial fibrosis and stimulate the repair of tubular epithelial cells in an irreversible model of unilateral ureteral obstruction

The growing number of patients suffering from chronic renal disease (CKD) is a challenge for the development of innovative therapies. Researchers have studied the therapeutic effects of cell therapy in acute kidney injury (AKI). However, the therapeutic effect of conditional medium (CM) in the CKD models have been rarely reported. Here, we examined the effects of umbilical cord derived‐mesenchymal stem cells (hUC‐MSCs) CM on renal fibrosis in a rat model of unilateral ureteral obstruction (UUO).

• Publication year

  2018

• Venue

  Nephrology

• Publication date

  2018-07-29

• Fields of study

  Medicine

• Identifiers
  DOI 10.1111/nep.13099PMID 28667820
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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