Changes in frequency of delayed graft function in deceased donor renal transplant recipient in a tertiary care center in Mexico.

A. L. Noriega-Salas,J. Alberú,Aczel I Sánchez-Cedillo,Luis Navarro-Vargas,Víctor Visag,Agustín Vintimilla-Moscoso,J. L. López-Jiménez,J. Madrigal-Bustamante,A. Contreras,M. Vilatobá-Chapa

Published 2015 in Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion

ABSTRACT

BACKGROUND Delayed graft function (DGF) is defined as the need for dialysis within the first seven days of transplantation. The frequency of DGF has decreased in the last five years compared with the previous 20 years of the kidney transplant program at a Mexican referral hospital. OBJECTIVE To determine the incidence and risk factors for DGF in the past five years (2009-2013). METHODS We analyzed a retrospective cohort of renal transplant recipients from deceased donors at our hospital between March 2009 and May 2013 (Period 2), and compared the results with a previously evaluated cohort (Period 1, between January 1990 and February 2009). RESULTS During the analyzed period, 78 deceased donor transplants were performed. The frequency of DGF was 9%. Multivariate analysis showed that recipient older age (OR: 1.074419; 95% CI: 1.0009-1.155116; p = 0.05), transoperative amines administration (OR: 7.73; 95% CI: 1.037-57.6; p = 0.046), and hypotension during surgery in the recipient (OR: 11.6; 95% CI: 1.33-100.8; p = 0.026) were risk factors for DGF. CONCLUSION The incidence of DGF has significantly decreased in the past five years when compared to the previous 20 years in our hospital.

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