Interferon gamma treatment prevents procollagen gene expression without affecting transforming growth factor-beta1 expression in pig serum-induced rat liver fibrosis in vivo.

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Journal of Hepatology

• Publication date

  1998-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0168-8278(98)80322-XPMID 9551686
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Herbal medicine Sho-saiko-to (TJ-9) prevents liver fibrosis and enzyme-altered lesions in rat liver cirrhosis induced by a choline-deficient L-amino acid-defined diet.

  1998cited by this paper
• Prolyl 4-hydroxylase inhibitor (HOE 077) inhibits pig serum-induced rat liver fibrosis by preventing stellate cell activation.

  1997cited by this paper
• Collagen content of liver biopsy specimens in patients with chronic hepatitis

  1996cited by this paper
• Contribution of immune response to the hepatic fibrosis induced by porcine serum

  1996cited by this paper
• Interferon gamma decreases hepatic stellate cell activation and extracellular matrix deposition in rat liver fibrosis

  1996cited by this paper
• The prolyl 4‐hydroxylase inhibitor HOE 077 prevents activation of Ito cells, reducing procollagen gene expression in rat liver fibrosis induced by choline‐deficient L‐amino acid‐defined diet

  1996cited by this paper
• Molecular mechanisms of antifibrotic effect of interferon gamma in bleomycin-mouse model of lung fibrosis: downregulation of TGF-beta and procollagen I and III gene expression.

  1995cited by this paper
• Signaling by the transforming growth factor-beta receptors.

  1995cited by this paper
• Interferon alfa and gamma inhibit proliferation and collagen synthesis of human ito cells in culture

  1995cited by this paper
• Collagen synthesis by human liver (myo)fibroblasts in culture: evidence fora regulatory role of IL-1β,IL-4, TGFβ and IFN gamma

  1995cited by this paper
• Signaling by the transforming growth factor-β receptor

  1995cited by this paper
• Hepatic stellate (ITO) cells: expanding roles for a liver-specific pericyte.

  1995cited by this paper
• Collagen synthesis by human liver (myo)fibroblasts in culture: evidence for a regulatory role of IL-1 beta, IL-4, TGF beta and IFN gamma.

  1995cited by this paper
• Prevention of fibrosis reduces enzyme-altered lesions in the rat liver.

  1994cited by this paper
• Modulation of transforming growth factor beta receptors of rat lipocytes during the hepatic wound healing response. Enhanced binding and reduced gene expression accompany cellular activation in culture and in vivo.

  1994cited by this paper
• Stimulation of collagen α1(I) gene expression is associated with lipid peroxidation in hepatocellular injury: A link to tissue fibrosis?

  1994cited by this paper
• Enhanced hepatic collagen type I mRNA expression into fat‐storing cells in a rodent model of hemochromatosis

  1994cited by this paper
• Seminars in medicine of the Beth Israel Hospital, Boston. The cellular basis of hepatic fibrosis. Mechanisms and treatment strategies.

  1993cited by this paper
• Improved sandwich enzyme-linked immunosorbent assays for transforming growth factor beta 1.

  1993cited by this paper
• The Cellular Basis of Hepatic Fibrosis -- Mechanisms and Treatment Strategies

  1993cited by this paper
• Role of mesenchymal cell populations in porcine serum‐induced rat liver fibrosis

  1992cited by this paper
• Activation of rat liver perisinusoidal lipocytes by transforming growth factors derived from myofibroblastlike cells. A potential mechanism of self perpetuation in liver fibrogenesis.

  1992cited by this paper
• Rat hepatic lipocytes express smooth muscle actin upon activation in vivo and in culture.

  1992cited by this paper
• Inhibition of rat hepatic lipocyte activation in culture by interferon‐γ

  1992cited by this paper
• Surival and prognostic factors in 212 Italian patients with genetic hemochromatosis

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• Expression cloning of the TGF-beta type II receptor, a functional transmembrane serine/threonine kinase.

  1992cited by this paper
• Transforming growth factors beta 1 and alpha in chronic liver disease. Effects of interferon alfa therapy.

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• Cellular localization of type I III and IV procollagen gene transcripts in normal and fibrotic human liver.

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• Activation of cultured rat hepatic lipocytes by Kupffer cell conditioned medium. Direct enhancement of matrix synthesis and stimulation of cell proliferation via induction of platelet-derived growth factor receptors.

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• Isolation, culture and main characteristics of mouse fat‐storing cells: Interaction with viruses

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  1989cited by this paper
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  1988cited by this paper
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  1985cited by this paper
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  1985cited by this paper
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  1985cited by this paper
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  1985cited by this paper
• Administration of recombinant interferon gamma to cancer patients enhances monocyte secretion of hydrogen peroxide.

  1985cited by this paper
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  1985cited by this paper
• Activation of mouse peritoneal macrophages in vitro and in vivo by interferon-gamma.

  1985cited by this paper
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  1985cited by this paper
• Immune interferon inhibits collagen synthesis by rheumatoid synovial cells associated wth decreaded levels of the procollagen mRNAs(FEBS 2156)

  1985cited by this paper
• Selective inhibition of human diploid fibroblast collagen synthesis by interferons.

  1984cited by this paper
• Synthesis in vitro of keratin polypeptides directed by mRNA isolated from newborn and adult mouse epidermis.

  1980cited by this paper
• Collagen types in normal and cirrhotic liver.

  1979cited by this paper
• A new microanalytical method for determination of hydroxyproline in connective tissues.

  1978cited by this paper
• Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose.

  1972cited by this paper
• Modifications of a specific assay for hydroxyproline in urine.

  1967cited by this paper

• A histone deacetylase inhibitor, largazole, decreases liver fibrosis and angiogenesis by inhibiting transforming growth factor‐β and vascular endothelial growth factor signalling

  2013cites this paper
• Polaprezinc prevents ongoing thioacetamide-induced liver fibrosis in rats.

  2012cites this paper
• Elevated Serum IL-18 and Interferon-Gamma in Medium-Term Survivors of Biliary Atresia

  2012cites this paper
• Inhibition of PDGF, TGF-β, and Abl signaling and reduction of liver fibrosis by the small molecule Bcr-Abl tyrosine kinase antagonist Nilotinib.

  2011cites this paper
• Antifibrotic effects of chronic baicalein administration in a CCl4 liver fibrosis model in rats.

  2010cites this paper
• IL-18 downregulates collagen production in human dermal fibroblasts via the ERK pathway.

  2010cites this paper
• Interferon-gamma inhibits adenosine A2A receptor function in hepatic stellate cells by STAT1-mediated repression of adenylyl cyclase.

  2010cites this paper
• A Novel Small Compound That Promotes Nuclear Translocation of YB-1 Ameliorates Experimental Hepatic Fibrosis in Mice*

  2010cites this paper
• PTK787/ZK22258 attenuates stellate cell activation and hepatic fibrosis in vivo by inhibiting VEGF signaling

  2009cites this paper
• Effect of natural interferon α on proliferation and apoptosis of hepatic stellate cells

  2009cites this paper
• Utility of plasma circulating mRNA as a marker to detect hepatic injury.

  2008cites this paper
• Liver fibrosis.

  2008cites this paper
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  2007cites this paper
• IFN-gamma abrogates profibrogenic TGF-beta signaling in liver by targeting expression of inhibitory and receptor Smads.

  2007cites this paper
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  2007cites this paper
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  2007cites this paper
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  2007cites this paper
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  2006cites this paper
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  2005cites this paper
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  2005cites this paper
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  2005cites this paper
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  2005cites this paper
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  2005cites this paper
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  2005cites this paper
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  2005cites this paper
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  2004cites this paper
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  2003cites this paper
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  2003cites this paper
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  1998cites this paper