Changes in Cell Wall Synthesis and Ultrastructure during Paradoxical Growth Effect of Caspofungin on Four Different Candida Species

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Antimicrobial Agents and Chemotherapy

• Publication date

  2010-11-08

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/AAC.00633-10PMID 21060107PMCID PMC3019691
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Prevalence rates and antifungal susceptibility profiles of the Candida parapsilosis species complex: results from a nationwide surveillance of candidaemia in Brazil.

  2010cited by this paper
• Paradoxical Growth of Candida dubliniensis Does Not Preclude In Vivo Response to Echinocandin Therapy

  2009cited by this paper
• Correlating Echinocandin MIC and Kinetic Inhibition of fks1 Mutant Glucan Synthases for Candida albicans: Implications for Interpretive Breakpoints

  2008cited by this paper
• Geographic and Temporal Trends in Isolation and Antifungal Susceptibility of Candida parapsilosis: a Global Assessment from the ARTEMIS DISK Antifungal Surveillance Program, 2001 to 2005

  2008cited by this paper
• Stimulation of Chitin Synthesis Rescues Candida albicans from Echinocandins

  2008cited by this paper
• Characteristics of biofilm formation by Candida tropicalis and antifungal resistance.

  2008cited by this paper
• Reduced Candida glabrata Susceptibility Secondary to an FKS1 Mutation Developed during Candidemia Treatment

  2008cited by this paper
• Paradoxical growth effects of the echinocandins caspofungin and micafungin, but not of anidulafungin, on clinical isolates of Candida albicans and C. dubliniensis

  2008cited by this paper
• Caspofungin-Resistant Candida tropicalis Strains Causing Breakthrough Fungemia in Patients at High Risk for Hematologic Malignancies

  2008cited by this paper
• Micafungin versus caspofungin for treatment of candidemia and other forms of invasive candidiasis.

  2007cited by this paper
• Paradoxical Growth Effect of Caspofungin Observed on Biofilms and Planktonic Cells of Five Different Candida Species

  2007cited by this paper
• The PKC, HOG and Ca2+ signalling pathways co‐ordinately regulate chitin synthesis in Candida albicans

  2007cited by this paper
• In Vitro Susceptibility of Invasive Isolates of Candida spp. to Anidulafungin, Caspofungin, and Micafungin: Six Years of Global Surveillance

  2007cited by this paper
• [The fungicidal activity and paradoxical effect of caspofungin against yeast. Influence of culture medium and incubation time].

  2007cited by this paper
• Putative role of beta-1,3 glucans in Candida albicans biofilm resistance.

  2007cited by this paper
• Antifungal susceptibility of 1000 Candida bloodstream isolates to 5 antifungal drugs: results of a multicenter study conducted in São Paulo, Brazil, 1995-2003.

  2007cited by this paper
• Paradoxical Effect of Echinocandins across Candida Species In Vitro: Evidence for Echinocandin-Specific and Candida Species-Related Differences

  2007influential reference
• Acquired Echinocandin Resistance in a Candida krusei Isolate Due to Modification of Glucan Synthase

  2007cited by this paper
• Attenuation of echinocandin activity at elevated concentrations: a review of the paradoxical effect

  2007cited by this paper
• In Vitro Study of Candida tropicalis Isolates Exhibiting Paradoxical Growth in the Presence of High Concentrations of Caspofungin

  2007cited by this paper
• Assessing Resistance to the Echinocandin Antifungal Drug Caspofungin in Candida albicans by Profiling Mutations in FKS1

  2006cited by this paper
• Escape of Candida from Caspofungin Inhibition at Concentrations above the MIC (Paradoxical Effect) Accomplished by Increased Cell Wall Chitin; Evidence for β-1,6-Glucan Synthesis Inhibition by Caspofungin

  2006cited by this paper
• Putative Role of β-1,3 Glucans in Candida albicans Biofilm Resistance

  2006cited by this paper
• Assessment of the Paradoxical Effect of Caspofungin in Therapy of Candidiasis

  2006cited by this paper
• Activities of Micafungin against 315 Invasive Clinical Isolates of Fluconazole-Resistant Candida spp

  2006cited by this paper
• Effects of Caspofungin against Candida guilliermondii and Candida parapsilosis

  2006cited by this paper
• Comparison of the Fungicidal Activities of Caspofungin and Amphotericin B against Candida glabrata

  2005cited by this paper
• Attenuation of the Activity of Caspofungin at High Concentrations against Candida albicans: Possible Role of Cell Wall Integrity and Calcineurin Pathways

  2005cited by this paper
• Paradoxical Effect of Caspofungin: Reduced Activity against Candida albicans at High Drug Concentrations

  2004cited by this paper
• Caspofungin: the first representative of a new antifungal class.

  2003cited by this paper
• Echinocandin antifungal drugs.

  2003cited by this paper
• Caspofungin Activity against Clinical Isolates of Fluconazole-Resistant Candida

  2003cited by this paper
• Morphological changes of Candida albicans induced by micafungin (FK463), a water-soluble echinocandin-like lipopeptide.

  2002cited by this paper
• Reference method for broth dilution antifungal susceptibility testing of yeasts, Approved standard-second edition

  2002cited by this paper
• Fungal beta(1,3)-D-glucan synthesis.

  2001cited by this paper
• Fungal β(1,3)-d-glucan synthesis

  2001cited by this paper
• Cell Wall and Secreted Proteins ofCandida albicans: Identification, Function, and Expression

  1998cited by this paper
• Increase in chitin as an essential response to defects in assembly of cell wall polymers in the ggp1delta mutant of Saccharomyces cerevisiae

  1997cited by this paper
• A Colorimetric Method for the Determination of Sugars

  1951cited by this paper
• A colorimetric method for the determination of N-acetylglucosamine and N-acetylchrondrosamine.

  1934cited by this paper

• In vitro biocontrol potential of plant extract-based formulation against infection structures of Phytophthora infestans along with lower non-target effects

  2025cites this paper
• Coniontins, lipopetaibiotics active against Candida auris identified from a microbial natural product fractionation library

  2025cites this paper
• Fluorene derivatives as potent antifungal and antibiofilm agents against fluconazole-resistant Candida albicans

  2025cites this paper
• A microbial natural product fractionation library screen with HRMS/MS dereplication identifies new lipopeptaibiotics against Candida auris

  2025cites this paper
• Adaptive morphological changes link to poor clinical outcomes by conferring echinocandin tolerance in Candida tropicalis

  2025cites this paper
• Died or Not Dyed: Assessment of Viability and Vitality Dyes on Planktonic Cells and Biofilms from Candida parapsilosis

  2024cites this paper
• Candida tropicalis PMT2 Is a Dispensable Gene for Viability but Required for Proper Interaction with the Host

  2024cites this paper
• BSC2 modulates AmB resistance via the maintenance of intracellular sodium/potassium ion homeostasis in Saccharomyces cerevisiae.

  2024cites this paper
• The putative error prone polymerase REV1 mediates DNA damage and drug resistance in Candida albicans

  2024cites this paper
• Rapid Antifungal Susceptibility Testing Based on Single-Cell Metabolism Analysis Using Stimulated Raman Scattering Imaging.

  2023cites this paper
• In Vitro Susceptibility Tests in the Context of Antifungal Resistance: Beyond Minimum Inhibitory Concentration in Candida spp.

  2023cites this paper
• Candida species causing fungal keratitis: molecular identification, antifungal susceptibility, biofilm formation, and clinical aspects

  2023cites this paper
• Caspofungin resistance in Candidaalbicans: genetic factors and synergistic compounds for combination therapies

  2022cites this paper
• Cellular and Extracellular Vesicle RNA Analysis in the Global Threat Fungus Candida auris

  2021cites this paper
• Analysis and application of a suite of recombinant endo-β(1,3)-d-glucanases for studying fungal cell walls

  2021cites this paper
• Adaptation of the emerging pathogenic yeast Candida auris to high caspofungin concentrations correlates with cell wall changes

  2021cites this paper
• BSC2 induces multidrug resistance via contributing to the formation of biofilm in Saccharomyces cerevisiae

  2021cites this paper
• Crosstalk between the calcineurin and cell wall integrity pathways prevents chitin overexpression in Candida albicans

  2021cites this paper
• In Situ Imaging of Candida albicans Hyphal Growth via Atomic Force Microscopy

  2020cites this paper
• Integrated transcriptional analysis of the cellular and extracellular vesicle RNA content of Candida auris in response to caspofungin

  2020cites this paper
• The effect of benzyl isothiocyanate on Candida albicans growth, cell size, morphogenesis, and ultrastructure

  2020cites this paper
• Minimal Inhibitory Concentration (MIC)-Phenomena in Candida albicans and Their Impact on the Diagnosis of Antifungal Resistance

  2019cites this paper
• Influence of subinhibitory antifungal concentrations on extracellular hydrolases and biofilm production by Candida albicans recovered from Egyptian patients

  2019cites this paper
• The Eagle Effect and Antibiotic-Induced Persistence: Two Sides of the Same Coin?

  2019cites this paper
• Role of Protein Mannosylation in the Candida tropicalis-Host Interaction

  2019cites this paper
• Role of protein phosphomannosylation in the Candida tropicalis–macrophage interaction

  2018cites this paper
• The cellular and molecular responses of Aspergillus fumigatus to the antifungal drug caspofungin

  2018influential citation
• Recent Insights into the Paradoxical Effect of Echinocandins

  2017cites this paper
• In vitro and in vivo antifungal activities and mechanism of heteropolytungstates against Candida species

  2017cites this paper
• Quantitative Analysis of Candida Cell Wall Components by Flow Cytometrywith Triple-Fluorescence Staining

  2017cites this paper
• Effect of Treatment with Caspofungin on the Diagnosis of Fungal Infections by Gamma Scintigraphy.

  2017cites this paper
• Fluconazole-Pyridoxine Bis-Triazolium Compounds with Potent Activity against Pathogenic Bacteria and Fungi Including Their Biofilm-Embedded Forms

  2017cites this paper
• The Emerging Pathogen Candida auris: Growth Phenotype, Virulence Factors, Activity of Antifungals, and Effect of SCY-078, a Novel Glucan Synthesis Inhibitor, on Growth Morphology and Biofilm Formation

  2017cites this paper
• Candida Biofilm Tolerance: Comparison of Planktonic and Biofilm Resistance Mechanisms

  2017cites this paper
• Creation, characterization and utilization of Cryptococcus neoformans mutants sensitive to micafungin

  2017cites this paper
• Evaluation of the possible influence of trailing and paradoxical effects on the clinical outcome of patients with candidemia.

  2017cites this paper
• Identification of the paradoxical effect of caspofungin and micafungin on Candida albicans growth in vitro using a growth curve methodology

  2017cites this paper
• AFM combined to ATR-FTIR reveals Candida cell wall changes under caspofungin treatment.

  2017cites this paper
• Nanoscopic cell-wall architecture of an immunogenic ligand in Candida albicans during antifungal drug treatment

  2016cites this paper
• Extracellular phospholipase production of oral Candida albicans isolates from smokers, diabetics, asthmatics, denture wearers and healthy individuals following brief exposure to polyene, echinocandin and azole antimycotics

  2016cites this paper
• Frequency of the Paradoxical Effect Measured Using the EUCAST Procedure with Micafungin, Anidulafungin, and Caspofungin against Candida Species Isolates Causing Candidemia

  2016cites this paper
• Caspofungin: Pharmacodynamics, pharmacokinetics, clinical uses and treatment outcomes

  2016cites this paper
• Antifungal Effect of Novel 2-Bromo-2-Chloro-2-(4-Chlorophenylsulfonyl)-1-Phenylethanone against Candida Strains

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• Exploring the In Vitro Resistance of Candida parapsilosis to Echinocandins

  2016cites this paper
• Highly Dynamic and Specific Phosphatidylinositol 4,5-Bisphosphate, Septin, and Cell Wall Integrity Pathway Responses Correlate with Caspofungin Activity against Candida albicans

  2016cites this paper
• Impact of short-term exposure of antifungal agents on hemolysin activity of oral Candida dubliniensis isolates from Kuwait and Sri Lanka.

  2016cites this paper
• Antifungal curcumin promotes chitin accumulation associated with decreased virulence of Sporothrix schenckii.

  2016cites this paper
• Drug resistance mechanisms and their regulation in non-albicans Candida species.

  2016cites this paper
• Possible role of hydrolytic enzymes (Sap, Kex2) in Candida albicans response to aromatic compounds bearing a sulfone moiety

  2016cites this paper
• Impact of brief exposure to antifungal agents on the post-antifungal effect and hemolysin activity of oral Candida albicans

  2015cites this paper
• Potential Microbiological Effects of Higher Dosing of Echinocandins.

  2015cites this paper
• The Eagle-Like Effect of the Echinocandins: Is It Relevant for Clinical Decisions?

  2015cites this paper
• Antifungal coatings by caspofungin immobilization onto biomaterials surfaces via a plasma polymer interlayer.

  2015cites this paper
• Antifungal pharmacokinetics and pharmacodynamics.

  2015cites this paper
• Tetrazole activity against Candida albicans. The role of KEX2 mutations in the sensitivity to (±)-1-[5-(2-chlorophenyl)-2H-tetrazol-2-yl]propan-2-yl acetate.

  2015cites this paper
• The lipopeptides pseudofactin II and surfactin effectively decrease Candida albicans adhesion and hydrophobicity

  2015cites this paper
• Atomic Force Microscopy Tools to Characterize the Physicochemical and Mechanical Properties of Pathogens

  2015cites this paper
• Combination of biochemical, molecular and biophysical approaches to investigate the impact of strain background and production process on the yeast cell wall composition and molecular architecture

  2014cites this paper
• The effect of K101 Nail Solution on Trichophyton rubrum and Candida albicans growth and ultrastructure

  2014cites this paper
• Antifungal Pharmacokinetics and Pharmacodynamics Subject Collection Human Fungal Pathogens Pneumocystis

  2014cites this paper
• Paradoxical antifungal activity and structural observations in biofilms formed by echinocandin-resistant Candida albicans clinical isolates.

  2014cites this paper
• , Olivier Determined by Microcalorimetry Planktonic and Biofilm Candida Species Anidulafungin , and Amphotericin B on Activities of Fluconazole , Caspofungin

  2014cites this paper
• Trailing or paradoxical growth of Aspergillus flavus exposed to caspofungin is independent of genotype.

  2014cites this paper
• Echinocandins--new antifungal agents.

  2014cites this paper
• Activities of Fluconazole, Caspofungin, Anidulafungin, and Amphotericin B on Planktonic and Biofilm Candida Species Determined by Microcalorimetry

  2014cites this paper
• Effect of a silver nanoparticles solution on staphylococcus aureus and candida spp.

  2014cites this paper
• PARADOXICAL GROWTH TO CASPOFUNGIN IN Candida albicans IS 1 ASSOCIATED WITH MULTIPLE CELL WALL REARRANGEMENTS AND 2 DECREASED VIRULENCE

  2013influential citation
• The Eagle-like effect of echinocandins: what’s in a name?

  2013cites this paper
• Nanoscale analysis of caspofungin-induced cell surface remodelling in Candida albicans.

  2013cites this paper
• The pharmacodynamics of antifungal agents against Aspergillus

  2013cites this paper
• Paradoxical Growth of Candida albicans in the Presence of Caspofungin Is Associated with Multiple Cell Wall Rearrangements and Decreased Virulence

  2013influential citation
• The History and Shaping of Caribbean Literature

  2013cites this paper
• Paradoxical effect to caspofungin in Candida species does not confer survival advantage in a Drosophila model of candidiasis

  2013cites this paper
• Species-Specific and Drug-Specific Differences in Susceptibility of Candida Biofilms to Echinocandins: Characterization of Less Common Bloodstream Isolates

  2013cites this paper
• Nanoscale Effects of Caspofungin against Two Yeast Species, Saccharomyces cerevisiae and Candida albicans

  2013cites this paper
• Mechanisms of Candida biofilm drug resistance.

  2013cites this paper
• Recent progress in the chemotherapy of human fungal diseases. Emphasis on 1,3-β-glucan synthase and chitin synthase inhibitors.

  2013cites this paper
• Unraveling the antifungal activity of a South American rattlesnake toxin crotamine.

  2013cites this paper
• Role of Innate Immune Receptors in Paradoxical Caspofungin Activity In Vivo in Preclinical Aspergillosis

  2012cites this paper
• Elevated Chitin Content Reduces the Susceptibility of Candida Species to Caspofungin

  2012cites this paper
• The high‐osmolarity glycerol– and cell wall integrity–MAP kinase pathways of Saccharomyces cerevisiae are involved in adaptation to the action of killer toxin HM‐1

  2012cites this paper
• Novel dendrimeric lipopeptides with antifungal activity.

  2012cites this paper
• The postantifungal and paradoxical effects of echinocandins against Candida spp.

  2012cites this paper
• Effect of nikkomycin Z and 50% human serum on the killing activity of high-concentration caspofungin against Candida species using time-kill methodology

  2012cites this paper
• Accurate Identification of Candida parapsilosis (Sensu Lato) by Use of Mitochondrial DNA and Real-Time PCR

  2012cites this paper
• The potential impact of antifungal drug resistance mechanisms on the host immune response to Candida

  2012cites this paper
• Mitochondrial DNA and Real-Time PCR parapsilosis ( Sensu Lato ) by Use of Accurate Identification of Candida

  2012cites this paper
• Accurate identification of Candida parapsilosis ( sensu lato ) using 1 mitochondrial DNA and real-time PCR 2

  2012cites this paper
• In vitro assessment of the antifungal and paradoxical activity of different echinocandins against Candida tropicalis biofilms.

  2011cites this paper
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  2011cites this paper
• Efg1 Controls Caspofungin-Induced Cell Aggregation of Candida albicans through the Adhesin Als1

  2011cites this paper
• Echinocandins: Are They All The Same?

  2011cites this paper
• Antimicrobial drug resistance is an obstacle to the treatment of numerous infectious diseases

  2010cites this paper