Mammalian CLASPs are required for mitotic spindle organization and kinetochore alignment

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Genes to Cells

• Publication date

  2006-08-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/j.1365-2443.2006.00990.xPMID 16866869
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Xorbit/CLASP links dynamic microtubules to chromosomes in the Xenopus meiotic spindle

  2006influential reference
• The CENP-F-like proteins HCP-1 and HCP-2 target CLASP to kinetochores to mediate chromosome segregation.

  2005cited by this paper
• Drosophila CLASP is required for the incorporation of microtubule subunits into fluxing kinetochore fibres

  2005cited by this paper
• CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex

  2005influential reference
• Length control of the metaphase spindle.

  2005cited by this paper
• Microtubule plus-end-tracking proteins: mechanisms and functions.

  2005cited by this paper
• The dynamic kinetochore-microtubule interface

  2004cited by this paper
• Mutations in orbit/mast reveal that the central spindle is comprised of two microtubule populations, those that initiate cleavage and those that propagate furrow ingression

  2004cited by this paper
• Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling.

  2003cited by this paper
• The spindle assembly and spindle position checkpoints.

  2003cited by this paper
• Human CLASP1 is an outer kinetochore component that regulates spindle microtubule dynamics.

  2003influential reference
• Visualization of Microtubule Growth in Cultured Neurons via the Use of EB3-GFP (End-Binding Protein 3-Green Fluorescent Protein)

  2003influential reference
• Stu1p is physically associated with beta-tubulin and is required for structural integrity of the mitotic spindle.

  2002cited by this paper
• LIS1, CLIP-170's Key to the Dynein/Dynactin Pathway

  2002influential reference
• A monomeric red fluorescent protein

  2002influential reference
• EB1 targets to kinetochores with attached, polymerizing microtubules.

  2002cited by this paper
• MAST/Orbit has a role in microtubule–kinetochore attachment and is essential for chromosome alignment and maintenance of spindle bipolarity

  2002influential reference
• Clasps are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts.

  2001influential reference
• Orbit, a Novel Microtubule-Associated Protein Essential for Mitosis in Drosophila melanogaster

  2000cited by this paper
• Mast, a conserved microtubule‐associated protein required for bipolar mitotic spindle organization

  2000cited by this paper
• Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III

  2000cited by this paper
• Evidence for a Role of CLIP-170 in the Establishment of Metaphase Chromosome Alignment

  1998cited by this paper
• Oscillating mitotic newt lung cell kinetochores are, on average, under tension and rarely push.

  1996cited by this paper
• Force generation by microtubule assembly/disassembly in mitosis and related movements.

  1995cited by this paper
• Poleward kinetochore fiber movement occurs during both metaphase and anaphase-A in newt lung cell mitosis

  1992cited by this paper
• Induction of multipolar mitoses in cultured cells: Decay and restructuring of the mitotic apparatus and distribution of centrioles

  1991cited by this paper
• MORPHOLOGICAL AND KINETIC ASPECTS OF MITOTIC ARREST BY AND RECOVERY FROM COLCEMID

  1966cited by this paper

• GAS2L1 Facilitates Golgi-Derived Microtubule Growth and Golgi Organization.

  2025cites this paper
• CLASP2 recognizes tubulins exposed at the microtubule plus-end in a nucleotide state–sensitive manner

  2023cites this paper
• Neuron navigators: A novel frontier with physiological and pathological implications.

  2023cites this paper
• Malat1 deficiency prevents neonatal heart regeneration by inducing cardiomyocyte binucleation

  2023cites this paper
• CLASPs stabilize the intermediate state between microtubule growth and catastrophe

  2022cites this paper
• Keep Calm and Carry on with Extra Centrosomes

  2022cites this paper
• CLASP2 stabilizes GDP-associated terminal tubulins to prevent microtubule catastrophe

  2022cites this paper
• CLASP1 is essential for neonatal lung function and survival in mice

  2022cites this paper
• Theileria’s Strategies and Effector Mechanisms for Host Cell Transformation: From Invasion to Immortalization

  2021cites this paper
• SOGA1 and SOGA2/MTCL1 are CLASP-interacting proteins required for faithful chromosome segregation in human cells

  2021cites this paper
• Biomechanics of chromosome alignment at the spindle midplane.

  2021cites this paper
• Microtubule poleward flux in human cells is driven by the coordinated action of four kinesins

  2020cites this paper
• CLASPs at a glance

  2020influential citation
• CLASP promotes microtubule bundling in metaphase spindle independently of Ase1/PRC1 in fission yeast

  2019cites this paper
• CLASP2 binding to curved microtubule tips promotes flux and stabilizes kinetochore attachments

  2019influential citation
• CLASP2 lattice-binding near microtubule plus ends stabilizes kinetochore attachments

  2019cites this paper
• Regulators of spindle microtubules and their mechanisms: Living together matters

  2018cites this paper
• Human CLASP2 specifically regulates microtubule catastrophe and rescue

  2018cites this paper
• GSK3-mediated CLASP2 phosphorylation modulates kinetochore dynamics

  2017cites this paper
• Clasp2 ensures mitotic fidelity and prevents differentiation of epidermal keratinocytes

  2017cites this paper
• The Microtubule-Stabilizing Protein CLASP1 Associates with the Theileria annulata Schizont Surface via Its Kinetochore-Binding Domain

  2017cites this paper
• The MgcRacGAP SxIP motif tethers Centralspindlin to microtubule plus ends in Xenopus laevis

  2017influential citation
• Mechanisms of Chromosome Congression during Mitosis

  2017cites this paper
• Kinetochore-microtubule interactions in chromosome segregation: lessons from yeast and mammalian cells.

  2017cites this paper
• Clasp2 ensures mitotic fidelity and prevents differentiation of epidermal keratinocytes

  2017cites this paper
• The Mitotic Spindle

  2016cites this paper
• Cell–Cell Interactions, Cell Polarity, and the Blood–Testis Barrier

  2015cites this paper
• Cell Polarity 1

  2015cites this paper
• CLASPs link focal adhesion-associated microtubule capture to localized exocytosis and adhesion site turnover

  2014cites this paper
• Regulated by the interplay of multiple CLASP domains, the localization of the TOGL2 domain to microtubules drives spindle formation in Saccharomyces cerevisiae

  2014cites this paper
• Microtubule organization and microtubule-associated proteins in plant cells.

  2014cites this paper
• JCB_201407095 1..12

  2014cites this paper
• The contribution of αβ-tubulin curvature to microtubule dynamics

  2014cites this paper
• Microtubule plus-end tracking proteins and their roles in cell division.

  2014influential citation
• Maintenance of epidermal architecture by CLASP2 and p120-catenin

  2013cites this paper
• Spatiotemporal regulation of microtubule function by human End Binding proteins

  2013influential citation
• Host microtubule plus‐end binding protein CLASP1 influences sequential steps in the Trypanosoma cruzi infection process

  2013cites this paper
• Microtubule plus-ends within a mitotic cell are ‘moving platforms’ with anchoring, signalling and force-coupling roles

  2012cites this paper
• Mitotic Spindle Form and Function

  2012cites this paper
• CLASPs prevent irreversible multipolarity by ensuring spindle-pole resistance to traction forces during chromosome alignment

  2012cites this paper
• Multiple Domains of Human CLASP Contribute to Microtubule Dynamics and Organization In Vitro and in Xenopus Egg Extracts

  2012cites this paper
• Multisite Phosphorylation Disrupts Arginine-Glutamate Salt Bridge Networks Required for Binding of Cytoplasmic Linker-associated Protein 2 (CLASP2) to End-binding Protein 1 (EB1)*

  2012cites this paper
• Prevention and Correction Mechanisms behind Anaphase Synchrony: Implications for the Genesis of Aneuploidy

  2011cites this paper
• Regulation of microtubule dynamics by TOG-domain proteins XMAP215/Dis1 and CLASP.

  2011cites this paper
• CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore‐microtubule dynamics to promote mitotic progression and fidelity

  2010cites this paper
• Force-Generating Proteins Assemble And Position Mitotic Spindles In Saccharomyces Cerevisiae

  2010influential citation
• Kinetochore-microtubule dynamics and attachment stability.

  2010cites this paper
• PRC1 Cooperates with CLASP1 to Organize Central Spindle Plasticity in Mitosis*

  2009cites this paper
• Motor-independent targeting of CLASPs to kinetochores by CENP-E promotes microtubule turnover and poleward flux.

  2009cites this paper
• Report of CLASPs to Kinetochores by CENP-E Promotes Microtubule Turnover and Poleward Flux

  2009cites this paper
• Stu1 inversely regulates kinetochore capture and spindle stability.

  2009influential citation
• Key players in chromosome segregation in Caenorhabditis elegans.

  2009influential citation
• Mechanisms for maintaining microtubule bundles.

  2008cites this paper
• Mechanisms of mitotic spindle assembly and function.

  2008cites this paper
• Stabilization of overlapping microtubules by fission yeast CLASP.

  2007cites this paper
• CLASP localizes in two discrete patterns on cortical microtubules and is required for cell morphogenesis and cell division in Arabidopsis

  2007cites this paper
• Index

  2006cites this paper