Severe necrotizing pancreatitis following combined hepatitis A and B vaccination

Necrotizing pancreatitis is a severe form of pancreatitis and is associated with substantial morbidity and mortality. We report a case of necrotizing pancreatitis that developed following combined hepatitis A and B vaccination. No other causes of pancreatitis could be determined. Although confirming the diagnosis is challenging, 3 main factors suggest a possible link to the vaccine: the chronology of the events, the patient's human leukocyte antigen genotype and the incongruent immune response to the vaccine components. This report serves to alert physicians to the possible development of necrotizing pancreatitis after vaccination.

• Publication year

  2007

• Venue

  Canadian Medical Association Journal

• Publication date

  2007-01-30

• Fields of study

  Medicine

• Identifiers
  DOI 10.1503/cmaj.060360PMID 17261831PMCID PMC1780095
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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