Caveolin-1 is required for signaling and membrane targeting of EphB1 receptor tyrosine kinase

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Journal of Cell Science

• Publication date

  2006-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1242/jcs.02946PMID 16723736
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Endothelial-specific expression of caveolin-1 impairs microvascular permeability and angiogenesis.

  2005cited by this paper
• Hypoxia up‐regulates expression of Eph receptors and ephrins in mouse skin

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• EphB2 as a Therapeutic Antibody Drug Target for the Treatment of Colorectal Cancer

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• Antiangiogenic and Antitumor Efficacy of EphA2 Receptor Antagonist

  2004cited by this paper
• EphB1-mediated Cell Migration Requires the Phosphorylation of Paxillin at Tyr-31/Tyr-118*

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• EphB 2 as a Therapeutic Antibody Drug Target for the Treatment of Colorectal Cancer

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• Ephrin signaling: One raft to rule them all? One raft to sort them? One raft to spread their call and in signaling bind them?

  2003cited by this paper
• Cholesterol Dependence of Vascular ERK1/2 Activation and Growth in Response to Stretch: Role of Endothelin-1

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• Cholesterol Dependence of Vascular ERK1/2 Activation and Growth in Response to Stretch

  2003cited by this paper
• Regulation of vascular endothelial growth factor receptor-2 activity by caveolin-1 and plasma membrane cholesterol.

  2003cited by this paper
• Identification of a structural determinant necessary for the localization and function of estrogen receptor alpha at the plasma membrane.

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• EphB1 recruits c-Src and p52Shc to activate MAPK/ERK and promote chemotaxis

  2003influential reference
• Identification of a Structural Determinant Necessary for the Localization and Function of Estrogen Receptor α at the Plasma Membrane

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• Endothelin-1 activates mesangial cell ERK1/2 via EGF-receptor transactivation and caveolin-1 interaction.

  2003influential reference
• Caveolae: anchored, multifunctional platforms in the lipid ocean.

  2003cited by this paper
• Mechanisms and functions of eph and ephrin signalling

  2002cited by this paper
• Soluble Eph A receptors inhibit tumor angiogenesis and progression in vivo

  2002cited by this paper
• The Insulin Receptor Catalyzes the Tyrosine Phosphorylation of Caveolin-1*

  2002cited by this paper
• In vivo footprinting of the human 11beta-hydroxysteroid dehydrogenase type 2 promoter: evidence for cell-specific regulation by Sp1 and Sp3.

  2002cited by this paper
• Caveolae: From Cell Biology to Animal Physiology

  2002cited by this paper
• The caveolar paradox: suppressing, inducing, and terminating eNOS signaling.

  2001cited by this paper
• Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities.

  2001cited by this paper
• Cholesterol Depletion Disrupts Caveolae and Insulin Receptor Signaling for Metabolic Control via Insulin Receptor Substrate-1, but Not for Mitogen-activated Protein Kinase Control*

  2001influential reference
• Immunoseparation of sphingolipid‐enriched membrane domains enriched in Src family protein tyrosine kinases and in the neuronal adhesion molecule TAG‐1 by anti‐GD3 ganglioside monoclonal antibody

  2001cited by this paper
• Loss of Caveolae, Vascular Dysfunction, and Pulmonary Defects in Caveolin-1 Gene-Disrupted Mice

  2001cited by this paper
• Cholesterol Depletion Inhibits Epidermal Growth Factor Receptor Transactivation by Angiotensin II in Vascular Smooth Muscle Cells

  2001cited by this paper
• Role of caveolin in hemodynamic force-mediated endothelial changes.

  2000cited by this paper
• Epidermal Growth Factor-stimulated Tyrosine Phosphorylation of Caveolin-1

  2000cited by this paper
• Epidermal Growth Factor-stimulated Tyrosine Phosphorylation of Caveolin-1 ENHANCED CAVEOLIN-1 TYROSINE PHOSPHORYLATION FOLLOWING ABERRANT EPIDERMAL GROWTH FACTOR RECEPTOR STATUS*

  2000cited by this paper
• Constitutive and growth factor-regulated phosphorylation of caveolin-1 occurs at the same site (Tyr-14) in vivo: identification of a c-Src/Cav-1/Grb7 signaling cassette.

  2000cited by this paper
• Caveolin-1 interacts with the insulin receptor and can differentially modulate insulin signaling in transfected Cos-7 cells and rat adipose cells.

  1999influential reference
• Membrane microdomains and caveolae.

  1999cited by this paper
• Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, angiopoietins, and ephrins in vascular development.

  1999cited by this paper
• Angiogenesis Activators and Inhibitors Differentially Regulate Caveolin-1 Expression and Caveolae Formation in Vascular Endothelial Cells

  1999cited by this paper
• Caveolin is an inhibitor of platelet-derived growth factor receptor signaling.

  1999cited by this paper
• Nck Recruitment to Eph Receptor, EphB1/ELK, Couples Ligand Activation to c-Jun Kinase*

  1998cited by this paper
• Caveolin‐mediated regulation of signaling along the p42/44 MAP kinase cascade in vivo

  1998influential reference
• Role of plasmalemmal caveolae in signal transduction.

  1998cited by this paper
• Targeted downregulation of caveolin‐1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade

  1998cited by this paper
• Cholesterol Depletion of Caveolae Causes Hyperactivation of Extracellular Signal-related Kinase (ERK)*

  1998cited by this paper
• Vascular Endothelial Growth Factor Induces Endothelial Fenestrations In Vitro

  1998cited by this paper
• Caveolins, a Family of Scaffolding Proteins for Organizing “Preassembled Signaling Complexes” at the Plasma Membrane*

  1998cited by this paper
• Caveolin Is an Activator of Insulin Receptor Signaling*

  1998cited by this paper
• Functions of lipid rafts in biological membranes.

  1998cited by this paper
• Use of cyclodextrins for manipulating cellular cholesterol content.

  1997cited by this paper
• Interaction of a Receptor Tyrosine Kinase, EGF-R, with Caveolins

  1997influential reference
• Identification of Peptide and Protein Ligands for the Caveolin-scaffolding Domain

  1997influential reference
• Insulin-stimulated Tyrosine Phosphorylation of Caveolin Is Specific for the Differentiated Adipocyte Phenotype in 3T3-L1 Cells*

  1997cited by this paper
• A Role for Caveolin in Transport of Cholesterol from Endoplasmic Reticulum to Plasma Membrane*

  1996influential reference
• Localization of Epidermal Growth Factor-stimulated Ras/Raf-1 Interaction to Caveolae Membrane (*)

  1996cited by this paper
• Endothelial Nitric Oxide Synthase Is Regulated by Tyrosine Phosphorylation and Interacts with Caveolin-1*

  1996influential reference
• Expression and Characterization of Recombinant Caveolin

  1996cited by this paper
• Cellular Cholesterol Efflux Mediated by Cyclodextrins

  1996cited by this paper
• Role of GTP Hydrolysis in Fission of Caveolae Directly from Plasma Membranes

  1996cited by this paper
• Co-purification and Direct Interaction of Ras with Caveolin, an Integral Membrane Protein of Caveolae Microdomains

  1996influential reference
• Expression of Caveolin-3 in Skeletal, Cardiac, and Smooth Muscle Cells

  1996influential reference
• Phosphorylation of Caveolin by Src Tyrosine Kinases

  1996cited by this paper
• Localization of Platelet-derived Growth Factor-stimulated Phosphorylation Cascade to Caveolae (*)

  1996influential reference
• Plasma membrane caveolae mediate the efflux of cellular free cholesterol.

  1995cited by this paper
• Angiogenesis in cancer, vascular, rheumatoid and other disease

  1995influential reference
• Evidence for a Regulated Interaction between Heterotrimeric G Proteins and Caveolin

  1995influential reference
• Filipin-sensitive caveolae-mediated transport in endothelium: reduced transcytosis, scavenger endocytosis, and capillary permeability of select macromolecules

  1994cited by this paper
• Characterization of caveolin-rich membrane domains isolated from an endothelial-rich source: implications for human disease

  1994cited by this paper
• Lowering the cholesterol content of MA104 cells inhibits receptor- mediated transport of folate

  1992cited by this paper
• The plasma membrane

  1988cited by this paper
• Highly specific antibody to Rous sarcoma virus src gene product recognizes a novel population of pp60v-src and pp60c-src molecules

  1985cited by this paper
• Monoclonal antibodies specific for the avian sarcoma virus transforming protein pp60src.

  1984cited by this paper
• Localization of the ASV src gene product to the plasma membrane of transformed cells by electron microscopic immunocytochemistry.

  1979cited by this paper

• Caveolae: Metabolic Platforms at the Crossroads of Health and Disease

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• Mechanisms for Regulating and Organizing Receptor Signaling by Endocytosis.

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• Caveolin-1 Regulates Cellular Metabolism: A Potential Therapeutic Target in Kidney Disease

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• Pathophysiologic Role of Molecules Determining Arteriovenous Differentiation in Adult Life

  2020cites this paper
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  2020cites this paper
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  2019cites this paper
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  2019influential citation
• Effect of Caveolin-1 upon Stat3-ptyr705 levels in breast and lung carcinoma cells.

  2019cites this paper
• EphB1 in Endothelial Cells Regulates Caveolae Formation and Endocytosis

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  2018cites this paper
• Reciprocal regulation of the Cadherin-11/Stat3 axis by caveolin-1 in mouse fibroblasts and lung carcinoma cells.

  2018cites this paper
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  2017influential citation
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  2016cites this paper
• Leptin suppresses adenosine triphosphate‐induced impairment of spinal cord astrocytes

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• Methylphenidate-triggered ROS generation promotes caveolae-mediated transcytosis via Rac1 signaling and c-Src-dependent caveolin-1 phosphorylation in human brain endothelial cells

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• Changes in protein expression and activation in rat arteriovenous fistula in vitro

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• Membrane-mediated regulation of vascular identity.

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• Charming neighborhoods on the cell surface: plasma membrane microdomains regulate receptor tyrosine kinase signaling.

  2015cites this paper
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• The role of syntenin-1 in modulating ephrin-b2 pathways in breast epithelial cells

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• Tagging Strategies Strongly Affect the Fate of Overexpressed Caveolin-1

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• Cross-talk between EphA2 and BRaf/CRaf Is a Key Determinant of Response to Dasatinib

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• Eph- and ephrin-dependent mechanisms in tumor and stem cell dynamics

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• Interaction of Human Follicle Stimulating Hormone Receptor with Caveolin within the cell membrane

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• Ligand stimulation induces clathrin- and Rab5-dependent downregulation of the kinase-dead EphB6 receptor preceded by the disruption of EphB6-Hsp90 interaction.

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• Role of caveolin-1 and caveolae signaling in endotoxemia and sepsis.

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• EphA2-Induced Angiogenesis in Ewing Sarcoma Cells Works through bFGF Production and Is Dependent on Caveolin-1

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• Internalization of pathogens in mammalian cells via CEACAM1

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• Caveolin-1: role in cell signaling.

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• Evaluating Caveolin Interactions: Do Proteins Interact with the Caveolin Scaffolding Domain through a Widespread Aromatic Residue-Rich Motif?

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• Essential roles of EphB receptors and EphrinB ligands in endothelial cell function and angiogenesis.

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