Gene transfer in hepatocarcinoma cell lines: in vitro optimization of a virus-free system.

No abstract is available for this paper.

• Publication year

  1996

• Venue

  Gene Therapy

• Publication date

  1996-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 8789797
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Virus-free transfer of the herpes simplex virus thymidine kinase gene followed by ganciclovir treatment induces tumor cell death.

  1996cited by this paper
• Effect of Herpes Simplex Virus Thymidine Kinase Expression Levels on Ganciclovir-Mediated Cytotoxicity and the “Bystander Effect”

  1995cited by this paper
• Cationic lipids for reporter gene and CFTR transfer to rat pulmonary epithelium.

  1995cited by this paper
• The Thymidine Kinase/Ganciclovir-Mediated “Suicide” Effect Is Variable in Different Tumor Cells

  1995cited by this paper
• Adenovirus-mediated gene therapy of hepatocellular carcinoma using cancer-specific gene expression.

  1995cited by this paper
• Systemic gene therapy of murine melanoma using tissue specific expression of the HSVtk gene involves an immune component.

  1994cited by this paper
• Tumor cell bystander killing in colonic carcinoma utilizing the Escherichia coli DeoD gene to generate toxic purines.

  1994cited by this paper
• Gene Expression Following Direct Injection of DNA into Liver

  1994cited by this paper
• Optimization of methods to achieve mRNA-mediated transfection of tumor cells in vitro and in vivo employing cationic liposome vectors.

  1994cited by this paper
• Retroviral Delivery of DNA into the Livers of Transgenic Mice Bearing Premalignant and Malignant Hepatocellular Carcinomas

  1994cited by this paper
• Bystander tumoricidal effect in the treatment of experimental brain tumors.

  1994cited by this paper
• Use of recombinant adenovirus to transfer the herpes simplex virus thymidine kinase (HSVtk) gene to thoracic neoplasms: an effective in vitro drug sensitization system.

  1994cited by this paper
• Enhanced cytotoxicity of antiviral drugs mediated by adenovirus directed transfer of the herpes simplex virus thymidine kinase gene in rat glioma cells.

  1994cited by this paper
• Direct gene transfer with DNA-liposome complexes in melanoma: expression, biologic activity, and lack of toxicity in humans.

  1993cited by this paper
• In Vitro Evidence That Metabolic Cooperation Is Responsible for the Bystander Effect Observed with HSV tk Retroviral Gene Therapy

  1993cited by this paper
• Transfer of a foreign gene into the brain using adenovirus vectors

  1993cited by this paper
• The "bystander effect": tumor regression when a fraction of the tumor mass is genetically modified.

  1993cited by this paper
• Gene transfer in vivo with DNA-liposome complexes: safety and acute toxicity in mice.

  1992cited by this paper
• In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors.

  1992cited by this paper
• Human gene therapy.

  1992cited by this paper
• Retroviral-mediated gene transfer into hepatocytes in vivo.

  1991cited by this paper
• Retroviral-mediated gene therapy for the treatment of hepatocellular carcinoma: an innovative approach for cancer therapy.

  1991cited by this paper
• Liposomes for the transformation of eukaryotic cells.

  1991cited by this paper
• Receptor-mediated gene delivery in vivo. Partial correction of genetic analbuminemia in Nagase rats.

  1991cited by this paper
• Curability of tumors bearing herpes thymidine kinase genes transferred by retroviral vectors.

  1990cited by this paper
• Construction of plasmids that express E. coli beta-galactosidase in mammalian cells.

  1989cited by this paper
• Targeting genes: delivery and persistent expression of a foreign gene driven by mammalian regulatory elements in vivo.

  1989cited by this paper
• Cationic liposome-mediated RNA transfection.

  1989cited by this paper
• Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.

  1987cited by this paper
• Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure.

  1987cited by this paper
• Cloning of the active thymidine kinase gene of herpes simplex virus type 1 in Escherichia coli K-12.

  1979cited by this paper

• Interpretation of the molecular mechanism and therapeutic potential of microRNA-155 in cardiovascular and cerebrovascular diseases (Review)

  2025cites this paper
• Isolation, expression, and characterization of the human ZCRB1 gene mapped to 12q12.

  2007cites this paper
• The potential of nucleic acid repair in functional genomics

  2001cites this paper
• Novel non-operative treatment and treatment strategies in pancreatic cancer

  2000cites this paper
• Inhibition of glioma cells in vitro and in vivo using a recombinant adenoviral vector containing an astrocyte-specific promoter

  2000cites this paper
• Connexin 43-enhanced suicide gene therapy using herpesviral vectors.

  2000cites this paper
• Molecular technology and pancreatic cancer

  2000cites this paper
• DNA vaccine against oncogenic hamster cells transformed by HPV16 E6/E7 oncogenes and the activated ras oncogene.

  1999cites this paper
• Nucleotide Exchange in Genomic DNA of Rat Hepatocytes Using RNA/DNA Oligonucleotides

  1999cites this paper
• Actions of HSVtk and connexin43 gene delivery on gap junctional communication and drug sensitization in hepatocellular carcinoma

  1998cites this paper
• Enhanced gene transfer into HuH-7 cells and primary rat hepatocytes using targeted liposomes and polyethylenimine.

  1998cites this paper
• High efficiency reporter gene transfection of vascular tissue in vitro and in vivo using a cationic lipid–DNA complex

  1997cites this paper
• A flow cytometric method for the rapid detection of beta-galactosidase transfected cells: an in vitro and in vivo study.

  1997cites this paper