Serous carcinoma is the most common type of epithelial ovarian cancer. In this review, we provide a comprehensive picture of ovarian serous cancers from multiple aspects: the first part of this review summarizes the morphological, histological, and immunological signatures of ovarian serous carcinoma; subsequently, we review the history of the evolvement of different grading systems used in ovarian serous cancer; in the end, we focus on characterizing the genetics that underlie the 2-tiered pathways through which ovarian serous cancers are believed to arise: the low-grade and the high-grade pathways.
Morphological and molecular basis of ovarian serous carcinoma
D. Rosen,Zhihong Zhang,Weiwei Shan,Jinsong Liu
Published 2010 in Journal of Biomedical Research
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- Publication year
2010
- Venue
Journal of Biomedical Research
- Publication date
2010-07-01
- Fields of study
Medicine
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Semantic Scholar, PubMed
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