A class of sulfonamides as carbonic anhydrase I and II inhibitors

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Journal of Enzyme Inhibition and Medicinal Chemistry

• Publication date

  2016-06-29

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1080/14756366.2016.1198900PMID 27353698
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The human carbonic anhydrase isoenzymes I and II (hCA I and II) inhibition effects of trimethoxyindane derivatives

  2016cited by this paper
• Ester Prodrugs of Ketoprofen: Synthesis, In Vitro Stability, In Vivo Biological Evaluation and In Silico Comparative Docking Studies Against COX-1 and COX-2.

  2016cited by this paper
• Polyphenolic content and biological properties of Avola almond (Prunus dulcis Mill. D.A. Webb) skin and its industrial byproducts

  2016cited by this paper
• Design, Synthesis, and Biological Evaluation of Potential Prodrugs Related to the Experimental Anticancer Agent Indotecan (LMP400).

  2016cited by this paper
• The effect of caffeic acid phenethyl ester (CAPE) on metabolic enzymes including acetylcholinesterase, butyrylcholinesterase, glutathione S-transferase, lactoperoxidase, and carbonic anhydrase isoenzymes I, II, IX, and XII

  2016cited by this paper
• Synthesis and carbonic anhydrase isoenzymes I, II, IX, and XII inhibitory effects of dimethoxybromophenol derivatives incorporating cyclopropane moieties.

  2015cited by this paper
• The impact of hydroquinone on acetylcholine esterase and certain human carbonic anhydrase isoenzymes (hCA I, II, IX, and XII)

  2015cited by this paper
• Antioxidant Activity and Polyphenol Content of Cranberries (Vaccinium macrocarpon)

  2015cited by this paper
• Carbonic anhydrase and acetylcholinesterase inhibitory effects of carbamates and sulfamoylcarbamates

  2015cited by this paper
• Plasmonic Particles that Hit Hypoxic Cells

  2015cited by this paper
• Characterization of one Novel Flavone and four New Source Compounds from the Bark of Millettia ovalifolia and In-Vitro Inhibition of Carbonic Anhydrase-II by the Novel Flavonoid

  2015cited by this paper
• Carbonic anhydrase inhibitors with dual-tail moieties to match the hydrophobic and hydrophilic halves of the carbonic anhydrase active site.

  2015cited by this paper
• N-Acylsulfonamides strongly inhibit human carbonic anhydrase isoenzymes I and II.

  2015cited by this paper
• Rosmarinic acid: a potent carbonic anhydrase isoenzymes inhibitor

  2014cited by this paper
• Synthesis and carbonic anhydrase isoenzymes I and II inhibitory effects of novel benzylamine derivatives

  2014cited by this paper
• Cyclic secondary sulfonamides: unusually good inhibitors of cancer-related carbonic anhydrase enzymes.

  2014cited by this paper
• Synthesis and Carbonic Anhydrase Inhibitory Effects of Novel Sulfamides Derived from 1‐Aminoindanes and Anilines

  2014cited by this paper
• Carbonic anhydrase inhibitory properties of novel sulfonamide derivatives of aminoindanes and aminotetralins

  2014cited by this paper
• Synthesis and Carbonic Anhydrase Isoenzymes Inhibitory Effects of Brominated Diphenylmethanone and Its Derivatives

  2014cited by this paper
• Inhibition studies of new ureido-substituted sulfonamides incorporating a GABA moiety against human carbonic anhydrase isoforms I-XIV.

  2014cited by this paper
• Oxidation of cyanobenzocycloheptatrienes: Synthesis, photooxygenation reaction and carbonic anhydrase isoenzymes inhibition properties of some new benzotropone derivatives.

  2014cited by this paper
• In vitro effect of a synthesized sulfonamido-based gallate on articular chondrocyte metabolism.

  2014cited by this paper
• Synthesis, Antioxidant, and Antiacetylcholinesterase Activities of Sulfonamide Derivatives of Dopamine‐Related Compounds

  2013cited by this paper
• Profiling of essential oils and polyphenolics of Salvia argentea and evaluation of its by-products antioxidant activity

  2013cited by this paper
• A Comprehensive Review on Biological Activities of P-Hydroxy Benzoic Acid and Its Derivatives

  2013cited by this paper
• Synthesis and carbonic anhydrase inhibitory properties of sulfamides structurally related to dopamine.

  2013cited by this paper
• A prodrug approach toward cancer-related carbonic anhydrase inhibition.

  2013cited by this paper
• (3,4-Dihydroxyphenyl)(2,3,4-trihydroxyphenyl)methanone and its derivatives as carbonic anhydrase isoenzymes inhibitors

  2013cited by this paper
• Phenolic Compounds of Pinus brutia Ten.: Chemical Investigation and Quantitative Analysis Using an Ultra-Performance Liquid Chromatography Tandem Mass Spectrometry with Electrospray Ionization Source

  2013cited by this paper
• Phenolic compounds as antioxidants: carbonic anhydrase isoenzymes inhibitors.

  2013cited by this paper
• New superacid synthesized (fluorinated) tertiary benzenesulfonamides acting as selective hCA IX inhibitors: toward a new mode of carbonic anhydrase inhibition by sulfonamides.

  2013cited by this paper
• Tricyclic sulfonamides incorporating benzothiopyrano[4,3-c]pyrazole and pyridothiopyrano[4,3-c]pyrazole effectively inhibit α- and β-carbonic anhydrase: X-ray crystallography and solution investigations on 15 isoforms.

  2012cited by this paper
• Multiple binding modes of inhibitors to carbonic anhydrases: how to design specific drugs targeting 15 different isoforms?

  2012cited by this paper
• In Vitro Inhibition of Human Carbonic Anhydrase I and II Isozymes with Natural Phenolic Compounds

  2011cited by this paper
• In vitro inhibition of α-carbonic anhydrase isozymes by some phenolic compounds.

  2011cited by this paper
• Carbonic anhydrase inhibitors: X-ray crystallographic studies for the binding of N-substituted benzenesulfonamides to human isoform II.

  2011cited by this paper
• Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins.

  2010cited by this paper
• Carbonic anhydrase inhibitors. Antioxidant polyphenols effectively inhibit mammalian isoforms I-XV.

  2010cited by this paper
• Carbonic anhydrase inhibitors. Inhibition of mammalian isoforms I-XIV with a series of natural product polyphenols and phenolic acids.

  2010cited by this paper
• Carbonic Anhydrase Inhibitors: Inhibition of Human Erythrocyte Isozymes I and II with a Series of Phenolic Acids

  2010cited by this paper
• Building block syntheses of gallic acid monomers and tris-(O-gallyl)-gallic acid dendrimers chemically attached to graphite powder: a comparative study of their uptake of Al(III) ions.

  2010cited by this paper
• Gallic acid, a major component of Toona sinensis leaf extracts, contains a ROS-mediated anti-cancer activity in human prostate cancer cells.

  2009cited by this paper
• Cloning, expression, post-translational modifications and inhibition studies on the latest mammalian carbonic anhydrase isoform, CA XV.

  2009cited by this paper
• Crystal structure of human carbonic anhydrase XIII and its complex with the inhibitor acetazolamide

  2009cited by this paper
• Prodrug Approaches for Enhancing the Bioavailability of Drugs with Low Solubility

  2009cited by this paper
• Carbonic anhydrase inhibitors. Inhibition of human erythrocyte isozymes I and II with a series of antioxidant phenols.

  2009cited by this paper
• Design and synthesis of novel nitrogen-containing polyhydroxylated aromatics as HIV-1 integrase inhibitors from caffeic acid phenethyl ester.

  2009cited by this paper
• Carbonic anhydrases: novel therapeutic applications for inhibitors and activators

  2008cited by this paper
• Anticonvulsant sulfonamides/sulfamates/sulfamides with carbonic anhydrase inhibitory activity: drug design and mechanism of action.

  2008cited by this paper
• The effect of ethanol on erythrocyte carbonic anhydrase isoenzymes activity: An in vitro and in vivo study

  2008cited by this paper
• Morphine inhibits erythrocyte carbonic anhydrase in vitro and in vivo.

  2007cited by this paper
• Inhibition of the Archaeal -Class (Cab) and ?-Class (Cam) Carbonic Anhydrases

  2007cited by this paper
• Gallic acid induces apoptosis in 3T3-L1 pre-adipocytes via a Fas- and mitochondrial-mediated pathway.

  2007cited by this paper
• An analysis of expression patterns of genes encoding proteins with catalytic activities

  2007cited by this paper
• Inhibition of the archaeal beta-class (Cab) and gamma-class (Cam) carbonic anhydrases.

  2007cited by this paper
• A perspective on quantitative structure–activity relationships and carbonic anhydrase inhibitors

  2006cited by this paper
• The Effects of Melatonin Hormone on Carbonic Anhydrase Enzyme Activity in Rainbow Trout (Oncorhynchus mykiss) Erythrocytes In Vitro and In Vivo

  2005cited by this paper
• In vitro and in vivo effects of dantrolene on carbonic anhydrase enzyme activities.

  2004cited by this paper
• Effects of Melatonin on Carbonic Anhydrase from Human Erythrocytes In Vitro and from Rat Erythrocytes In Vivo

  2004cited by this paper
• Characterization of CA XIII, a Novel Member of the Carbonic Anhydrase Isozyme Family*

  2004cited by this paper
• Effect of vitamin E on carbonic anhydrase enzyme activity in rainbow trout (Oncorhynchus mykiss) erythrocytes in vitro and in vivo.

  2004cited by this paper
• Carbonic anhydrase inhibitors

  2003cited by this paper
• Nonaromatic sulfonamide group as an ideal anchor for potent human carbonic anhydrase inhibitors: role of hydrogen-bonding networks in ligand binding and drug design.

  2002cited by this paper
• Human carbonic anhydrase XIV (CA14): cDNA cloning, mRNA expression, and mapping to chromosome 1.

  1999cited by this paper
• Human Mitochondrial Carbonic Anhydrase VB

  1999cited by this paper
• Characterization of the human gene for a newly discovered carbonic anhydrase, CA VII, and its localization to chromosome 16.

  1991cited by this paper
• Sulphonamide complexes of human carbonic anhydrases. Ultraviolet difference spectroscopy.

  1970cited by this paper
• Esterase activities of human carbonic anhydrases B and C.

  1967cited by this paper

• Click Chemistry-Enabled Parallel Synthesis of N-Acyl Sulfonamides and Their Evaluation as Carbonic Anhydrase Inhibitors

  2026cites this paper
• Design synthesis and antibacterial evaluation of naphthyl sulfonamide derivatives supported by computational and experimental studies

  2026cites this paper
• Expanding chemical space of N-acyl sulfonamides for carbonic anhydrase inhibitor discovery.

  2025cites this paper
• Exploring Indole-Linked Triazole Sulfonamide Derivatives as Potent Mycobacterial Carbonic Anhydrase Inhibitors: Leveraging a Tail Approach for the Design, Synthesis, and In Silico Studies─An In-Depth Multidisciplinary Study.

  2025cites this paper
• Comprehensive Insights Into Sulfanilamido‐Based Medicinal Design and Research

  2025cites this paper
• Structure-based design of an aromatic helical foldamer–protein interface

  2025cites this paper
• Bufalin Inhibits Tumorigenesis and SREBP-1-Mediated Lipogenesis in Hepatocellular Carcinoma via Modulating the ATP1A1/CA2 Axis.

  2023cites this paper
• Dimeric polyphenols to pave the way for new antimalarial drugs.

  2023cites this paper
• Fused Tetrahydroquinolines Are Interfering with Your Assay

  2023cites this paper
• Isofraxidin: Antioxidant, Anti‐carbonic Anhydrase, Anti‐cholinesterase, Anti‐diabetic, and in Silico Properties

  2023cites this paper
• Investigation of carbonic anhydrase inhibitory potency of (Z/E)-alkyl N'-benzyl-N-(arylsulfonyl)-carbamimidothioates.

  2023cites this paper
• Efficient Ligand Discovery Using Sulfur(VI) Fluoride Reactive Fragments

  2023cites this paper
• Copper based azo dye catalysts for phenoxazinone synthase mimicking efficiency: structure characterization and bioactivity evaluation

  2023cites this paper
• Pyrazolo[4,3-c]pyridine Sulfonamides as Carbonic Anhydrase Inhibitors: Synthesis, Biological and In Silico Studies

  2022cites this paper
• Synthesis, characterization and docking studies of benzenesulfonamide derivatives containing 1,2,3-triazole as potential ınhibitor of carbonic anhydrase I-II enzymes

  2022cites this paper
• Exploring the multi-target enzyme inhibition potential of new sulfonamido-thiazoline derivatives; Synthesis and computational studies

  2022cites this paper
• Synthesis and Antimicrobial Activity of New Heteroaryl(aryl) Thiazole Derivatives Molecular Docking Studies

  2022cites this paper
• Isoxazole Derivatives against Carbonic Anhydrase: Synthesis, Molecular Docking, MD Simulations, and Free Energy Calculations Coupled with In Vitro Studies

  2022cites this paper
• Biological activity and molecular docking studies of some N‐phenylsulfonamides against cholinesterases and carbonic anhydrase isoenzymes

  2022cites this paper
• Recent Advances on Biological Active Sulfonamide based Hybrid Compounds Part A: Two-Component Sulfonamide Hybrids.

  2022cites this paper
• Design, Synthesis and Molecular Docking Study of Novel 3-Phenyl-β-Alanine-Based Oxadiazole Analogues as Potent Carbonic Anhydrase II Inhibitors

  2022cites this paper
• Triazolo Based-Thiadiazole Derivatives. Synthesis, Biological Evaluation and Molecular Docking Studies

  2021cites this paper
• New amino acid clubbed Schiff bases inhibit carbonic anhydrase II, α-glucosidase, and urease enzymes: in silico and in vitro

  2021cites this paper
• Novel inhibitors with sulfamethazine backbone: synthesis and biological study of multi-target cholinesterases and α-glucosidase inhibitors

  2021cites this paper
• Polyhydroxybenzoic acid derivatives as potential new antimalarial agents

  2021cites this paper
• Discovery of sulfadrug–pyrrole conjugates as carbonic anhydrase and acetylcholinesterase inhibitors

  2021cites this paper
• Antitumor activity, X-Ray crystallography, in silico study of some-sulfamido-phosphonates. Identification of pharmacophore sites

  2021cites this paper
• New amino acid clubbed Schiff bases inhibit carbonic anhydrase II, α-glucosidase, and urease enzymes: in silico and in vitro

  2021cites this paper
• Triosephosphate isomerase, carbonic anhydrase, and creatinine kinase‐brain isoform are possible antigen targets in patients with achalasia

  2020cites this paper
• A new series of sulfa drugs containing pyrazolyl acylthiourea moiety: Synthesis, experimental and theoretical spectral characterization and molecular docking studies

  2020cites this paper
• Some sulfonamides as aldose reductase inhibitors: therapeutic approach in diabetes

  2020cites this paper
• Acidity of arylsulfonamides as function of quantum chemical parameters of sulfonamide nitrogen

  2019cites this paper
• Association between the expression of carbonic anhydrase II and clinicopathological features of hepatocellular carcinoma.

  2019cites this paper
• Synthesis and investigation of anticancer, antibacterial activities and carbonic anhydrase, acetylcholinesterase inhibition profiles of novel (3aR,4S,7R,7aS)-2-[4-[1-acetyl-5-(aryl/heteroaryl)-4,5-dihydro-1H-pyrazol-3-yl]phenyl]-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3(2H)-diones

  2019cites this paper
• Aryl azide-sulfonamide hybrids induce cellular apoptosis: synthesis and preliminary screening of their cytotoxicity in human HCT116 and A549 cancer cell lines

  2019cites this paper
• Synthesis of sulfonamide, amide and amine hybrid pharmacophore, an entry of new class of carbonic anhydrase II inhibitors and evaluation of chemo-informatics and binding analysis.

  2019cites this paper
• The inhibition effects of some sulfonamides on human serum paraoxonase-1 (hPON1)

  2019cites this paper
• Investigation of the effects of some sulfonamides on acetylcholinesterase and carbonic anhydrase enzymes

  2019cites this paper
• Synthesis, molecular docking analysis and carbonic anhydrase I-II inhibitory evaluation of new sulfonamide derivatives.

  2019cites this paper
• Characterization and inhibition effects of some metal ions on carbonic anhydrase enzyme from Kangal Akkaraman sheep

  2018cites this paper
• The in vivo effects of cefazolin, cefuroxime, and cefoperazon on the carbonic anhydrase in different rat tissues

  2018cites this paper
• Serum carbonic anhydrase I and II autoantibodies in patients with chronic lymphocytic leukaemia

  2018cites this paper
• Novel thymol bearing oxypropanolamine derivatives as potent some metabolic enzyme inhibitors - Their antidiabetic, anticholinergic and antibacterial potentials.

  2018cites this paper
• Sulfonamide inhibitors: a patent review 2013-present

  2018cites this paper
• Autoantibodies Against Carbonic Anhydrase I and II in Patients with Acute Myeloid Leukemia

  2017cites this paper
• Synthesis of 2‐amino‐3‐cyanopyridine derivatives and investigation of their carbonic anhydrase inhibition effects

  2017cites this paper
• Synthesis and investigation of antibacterial activities and carbonic anhydrase and acetyl cholinesterase inhibition profiles of novel 4,5-dihydropyrazol and pyrazolyl-thiazole derivatives containing methanoisoindol-1,3-dion unit

  2017cites this paper
• Synthesis and bioactivity of several new hetaryl sulfonamides

  2017cites this paper
• Novel NHC Precursors: Synthesis, Characterization, and Carbonic Anhydrase and Acetylcholinesterase Inhibitory Properties

  2017cites this paper
• Novel antioxidant bromophenols with acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase inhibitory actions.

  2017cites this paper
• Assessment of the inhibitory effects and molecular docking of some sulfonamides on human serum paraoxonase 1

  2017cites this paper
• Secondary Sulfonamides as Effective Lactoperoxidase Inhibitors

  2017cites this paper