Expression analysis of human β-secretase in transgenic tomato fruits.

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Protein Expression and Purification

• Publication date

  2012-03-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1016/j.pep.2011.11.012PMID 22178732
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Advances in plant molecular farming.

  2011cited by this paper
• High-level expression of a human β-site APP cleaving enzyme in transgenic tobacco chloroplasts and its immunogenicity in mice

  2010cited by this paper
• Overview of expression of hepatitis B surface antigen in transgenic plants.

  2010cited by this paper
• Transient and stable expression of hepatitis B surface antigen in tomato (Lycopersicon esculentum L.)

  2008cited by this paper
• Expression of modified gene encoding functional human α-1-antitrypsin protein in transgenic tomato plants

  2008cited by this paper
• Transgenic tomatoes expressing human beta-amyloid for use as a vaccine against Alzheimer’s disease

  2008cited by this paper
• Assessment of the utility of the tomato fruit-specific E8 promoter for driving vaccine antigen expression

  2008influential reference
• Cholera toxin B protein in transgenic tomato fruit induces systemic immune response in mice

  2007cited by this paper
• A novel beta-site amyloid precursor protein cleaving enzyme (BACE) isoform regulated by nonsense-mediated mRNA decay and proteasome-dependent degradation.

  2007cited by this paper
• Partial Reduction of BACE1 Has Dramatic Effects on Alzheimer Plaque and Synaptic Pathology in APP Transgenic Mice*

  2007cited by this paper
• Qualitative and quantitative evaluation of protein extraction protocols for apple and strawberry fruit suitable for two-dimensional electrophoresis and mass spectrometry analysis.

  2007cited by this paper
• Ubiquitin fusion enhances cholera toxin B subunit expression in transgenic plants and the plant-expressed protein binds GM1 receptors more efficiently.

  2006cited by this paper
• A general procedure for the purification of human beta-secretase expressed in Escherichia coli.

  2004cited by this paper
• Expression of human β-amyloid peptide in transgenic potato

  2003cited by this paper
• Expression of ORF2 partial gene of hepatitis E virus in tomatoes and immunoactivity of expression products.

  2003cited by this paper
• Recombinant insect cell expression and purification of human beta-secretase (BACE-1) for X-ray crystallography.

  2002cited by this paper
• Immunomodulators and delivery systems for vaccination by mucosal routes.

  2001cited by this paper
• Oral immunization of mice with transgenic tomato fruit expressing respiratory syncytial virus-F protein induces a systemic immune response

  2000cited by this paper
• Characterization of Alzheimer's beta -secretase protein BACE. A pepsin family member with unusual properties.

  2000cited by this paper
• Characterization of Alzheimer's β-Secretase Protein BACE

  2000cited by this paper
• Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE.

  1999cited by this paper
• Separation of cis elements responsive to ethylene, fruit development, and ripening in the 5′-flanking region of the ripening-related E8 gene

  1998cited by this paper
• Characterization of a DNA-binding protein that interacts with 5' flanking regions of two fruit-ripening genes.

  1997cited by this paper
• Identification of a 50-kDa systemin-binding protein in tomato plasma membranes having Kex2p-like properties.

  1994cited by this paper
• Isolation of plant DNA from fresh tissue

  1990cited by this paper
• A rapid total DNA preparation procedure for fresh plant tissue

  1990cited by this paper
• A dual-labeling method for identifying differentially expressed genes: use in the identification of cDNA clones that hybridize to RNAs whose abundance in tomato flowers is potentially regulated by gibberellins.

  1989cited by this paper
• A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

  1976cited by this paper
• The FASEB Journal • Research Communication Amyloid-beta reduction by memapsin 2 (beta-secretase) immunization

  year unknowncited by this paper

• Current Advances of Plant-Based Vaccines for Neurodegenerative Diseases

  2023influential citation
• Identification of essential element determining fruit-specific transcriptional activity in the tomato HISTIDINE DECARBOXYLASE A gene promoter

  2022cites this paper
• Functional characterization of a strong promoter of the early light-inducible protein gene from tomato

  2019cites this paper
• Prospects for the Production of Recombinant Therapeutic Proteins and Peptides in Plants: Special Focus on Angiotensin I-Converting Enzyme Inhibitory (ACEI) Peptides

  2019cites this paper
• Synthesis and Development of BACE 1 Inhibitor for Alzheimer’s Diseases from Medicinal Plants

  2018cites this paper
• Plastid Molecular Pharming II. Production of Biopharmaceuticals by Plastid Transformation.

  2017cites this paper
• Molecular Farming Using Transgenic Approaches

  2016cites this paper
• Tomato (Solanum lycopersicum L.) in the service of biotechnology

  2015cites this paper
• Plant-based vaccines for Alzheimer's disease: an

  2014cites this paper
• The laccase promoter of potato confers strong tuber-specific expression in transgenic plants

  2014cites this paper
• Plant-based vaccines for Alzheimer's disease: an overview

  2014cites this paper
• Production of Pharmaceutical Proteins in Solanaceae Food Crops

  2013cites this paper