Angiotensin II receptor blockade improves nerve function, modulates nerve blood flow and stimulates endoneurial angiogenesis in streptozotocin-diabetic ratsand nerve function

No abstract is available for this paper.

• Publication year

  1993

• Venue

  Diabetologia

• Publication date

  1993-12-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1007/BF00400799PMID 8307249
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Angiotensin converting enzyme inhibition prevents development of muscle and nerve dysfunction and stimulates angiogenesis in streptozotocin-diabetic rats

  2004influential reference
• Pharmacological manipulation of vascular endothelium function in non-diabetic and streptozotocin-diabetic rats: effects on nerve conduction, hypoxic resistance and endoneurial capillarization

  1993cited by this paper
• Anti-oxidant treatment prevents the development of peripheral nerve dysfunction in streptozotocin-diabetic rats

  1993cited by this paper
• Prevention and reversal of motor and sensory peripheral nerve conduction abnormalities in streptozotocin-diabetic rats by the prostacyclin analogue iloprost

  1993cited by this paper
• Inhibition of cAMP- and Ca-dependent Cl- secretion by phorbol esters: inhibition of basolateral K+ channels.

  1993cited by this paper
• Nerve function in experimental diabetes in rats: effects of electrical stimulation.

  1993cited by this paper
• Functional consequences of streptozotocin-induced diabetes mellitus, with particular reference to the cardiovascular system.

  1992influential reference
• The effect of the calcium antagonist nifedipine on peripheral nerve function in streptozotocin-diabetic rats

  1992cited by this paper
• Aldose reductase and myo-inositol in endothelial cell dysfunction caused by elevated glucose.

  1992cited by this paper
• Correlations between nerve function and tissue oxygenation in diabetic patients: further clues to the aetiology of diabetic neuropathy?

  1992cited by this paper
• Elevated serum angiotensin I converting enzyme activity in type I insulin-dependent diabetic subjects with persistent microalbuminuria

  1992cited by this paper
• Effects of aminoguanidine on peripheral nerve function and polyol pathway metabolites in streptozotocin-diabetic rats

  1992cited by this paper
• Elevated serum angiotensin I converting enzyme activity in type I, insulin-dependent diabetic subjects with persistent microalbuminuria

  1992cited by this paper
• Exercise-induced conduction velocity increment: a marker of impaired peripheral nerve blood flow in diabetic neuropathy

  1992cited by this paper
• Impaired endothelium-dependent and independent vasodilation in patients with Type 2 (non-insulin-dependent) diabetes mellitus

  1992cited by this paper
• Impaired contraction and relaxation in aorta from streptozotocin-diabetic rats: Role of polyol pathway

  1992cited by this paper
• Effects of Chronic α-Adrenergic Receptor Blockade on Peripheral Nerve Conduction, Hypoxic Resistance, Polyols, Na+-K+-ATPase Activity, and Vascular Supply in STZ-D Rats

  1991influential reference
• Nerve blood flow in early experimental diabetes in rats: relation to conduction deficits.

  1991influential reference
• Essential Fatty Acid Diet Supplementation: Effects on Peripheral Nerve and Skeletal Muscle Function and Capillarization in Streptozocin-Induced Diabetic Rats

  1991cited by this paper
• Advanced glycosylation products quench nitric oxide and mediate defective endothelium-dependent vasodilatation in experimental diabetes.

  1991cited by this paper
• EDRF-mediated shear-induced dilation opposes myogenic vasoconstriction in small rabbit arteries.

  1991cited by this paper
• Aminoguanidine effects on nerve blood flow, vascular permeability, electrophysiology, and oxygen free radicals.

  1991cited by this paper
• Central hypoxaemia in rats provokes neurological defects similar to those seen in experimental diabetes mellitus: evidence for a partial role of endoneurial hypoxia in diabetic neuropathy.

  1991cited by this paper
• Regulatory functions of the vascular endothelium.

  1990cited by this paper
• Effects of ACE-inhibition on glucose metabolism.

  1990cited by this paper
• Distribution of Free Amino Acids in Streptozotocin-Induced Diabetic Pregnant Rats, Their Placentae and Fetuses

  1990cited by this paper
• Diabetes mellitus, the renin-angiotensin system, and angiotensin-converting enzyme inhibition.

  1990cited by this paper
• Hypoxic neuropathy: relevance to human diabetic neuropathy

  1990cited by this paper
• Microangiopathy in human diabetic neuropathy: relationship between capillary abnormalities and the severity of neuropathy

  1989cited by this paper
• The effect of aldose reductase inhibition on the pattern of nerve conduction deficits in diabetic rats.

  1989cited by this paper
• Nerve blood flow and oxygen delivery in normal, diabetic, and ischemic neuropathy.

  1989cited by this paper
• Prostacyclin and noradrenaline in peripheral nerve of chronic experimental diabetes in rats.

  1989cited by this paper
• Angiogenesis: the growth of the vascular system

  1989cited by this paper
• Repeated measurements of cerebral blood flow in rats. Comparisons between the hydrogen clearance method and laser Doppler flowmetry.

  1988cited by this paper
• Pattern of myelinated fibre loss in the sural nerve in neuropathy related to Type 1 (insulin-dependent) diabetes

  1988cited by this paper
• Is resistance to ischaemic conduction failure induced by hypoxia?

  1988cited by this paper
• Regional blood flow in resting and stimulated sciatic nerve of diabetic rats.

  1988influential reference
• Sciatic nerve blood flow response to carbon dioxide.

  1988cited by this paper
• Dietary calcium and iron interaction on hematocrit in the shr

  1988cited by this paper
• Abnormalities of endoneurial microvessels and sural nerve pathology in diabetic neuropathy

  1987cited by this paper
• Reduced glomerular angiotensin II receptor density in diabetes mellitus in the rat: time course and mechanism.

  1987cited by this paper
• Experimental chronic hypoxic neuropathy: relevance to diabetic neuropathy.

  1986cited by this paper
• Sural nerve oxygen tension in diabetes.

  1986cited by this paper
• The effects of Sorbinil on peripheral nerve conduction velocity, polyol concentrations and morphology in the streptozotocin-diabetic rat

  1986influential reference
• Reduced number of angiotensin II receptors on platelets in insulin-dependent diabetes.

  1986cited by this paper
• Angiogenesis : the growth of the vascular system

  1986cited by this paper
• Blood flow in rat sciatic nerve during hypotension.

  1985cited by this paper
• Sciatic nerve blood flow measured by laser Doppler flowmetry and [14C]iodoantipyrine.

  1985cited by this paper
• Properties of ICI 128,436, a novel aldose reductase inhibitor, and its effects on diabetic complications in the rat.

  1985cited by this paper
• Neurohumoral control of the circulation

  1985cited by this paper
• Endoneurial blood flow and oxygen tension in the sciatic nerves of rats with experimental diabetic neuropathy.

  1984cited by this paper
• Increased vasopressor responsiveness to angiotensin II in Type 1 (insulin-dependent) diabetic patients without complications

  1984cited by this paper
• The effect of long-term vasodilatation on capillary growth and performance in rabbit heart and skeletal muscle.

  1984influential reference
• A descriptive study of the blood vessels of the sciatic nerve in the rat, man and other mammals.

  1984cited by this paper
• Renin-angiotensin system and prostacyclin biosynthesis in streptozotocin diabetic rats.

  1983cited by this paper
• PLASMA ANGIOTENSIN II AND ALDOSTERONE IN UNSELECTED DIABETIC PATIENTS

  1982cited by this paper
• The natriuretic hormone: recent developments.

  1982cited by this paper
• Changes in Blood Pressure, Body Fluids, Circulating Angiotensin II and Aldosterone, with Improved Diabetic Control

  1982cited by this paper
• INCREASED PLASMA RENIN ACTIVITY IN TYPE 1 DIABETES WITH MICROVASCULAR DISEASE

  1982cited by this paper
• PLASMA ANGIOTENSIN II AND THE CONTROL OF DIABETES MELLITUS

  1980cited by this paper
• Plasma renin activity in diabetes mellitus.

  1979cited by this paper
• Evidence that angiotensin enhances transmitter release during sympathetic nerve stimulation

  1971cited by this paper
• The effects of hypoxia on the excitability of the isolated peripheral nerves of alloxan-diabetic rats.

  1969cited by this paper

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  2023cites this paper
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• Treatment for diabetic peripheral neuropathy: What have we learned from animal models?

  2021cites this paper
• Non-glucose risk factors in the pathogenesis of diabetic peripheral neuropathy

  2020cites this paper
• Diabetic neuropathy and the sensory neuron: New aspects of pathogenesis and their treatment implications

  2018cites this paper
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  2015cites this paper
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  2013cites this paper
• Collateral circulation in CTO

  2013cites this paper
• Protective effects of mineralocorticoid receptor blockade against neuropathy in experimental diabetic rats

  2012cites this paper
• Aberrant angiogenesis: The gateway to diabetic complications

  2012cites this paper
• Diabetic peripheral neuropathy: primarypathologies and the role of physical activityas a treatment intervention. A preliminary study

  2011cites this paper
• Peripheral neuropathy in hypertension

  2011cites this paper
• Early potential impairment of renal sensory nerves in streptozotocin-induced diabetic rats: role of neurokinin receptors.

  2011cites this paper
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  2010cites this paper
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  2010cites this paper
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  2009cites this paper
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  2009cites this paper
• Impaired responsiveness of renal sensory nerves in streptozotocin-treated rats and obese Zucker diabetic fatty rats: role of angiotensin.

  2008cites this paper
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  2008cites this paper
• The renin angiotensin system in the regulation of angiogenesis.

  2007cites this paper
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  2007cites this paper
• Regulation of angiogenesis and angiogenic factors by cardiovascular medications.

  2007cites this paper
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  2006cites this paper
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  2004cites this paper
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  2003cites this paper
• Angiotensin-converting enzyme inhibitor promotes coronary collateral circulation in patients with coronary artery disease.

  2003cites this paper
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  2003cites this paper
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  2002cites this paper
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  2002cites this paper
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  2000cites this paper
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  1999cites this paper
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  1999cites this paper
• Experimental diabetic neuropathy: an update

  1999cites this paper
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• Effects of body and hindlimb temperature on laser Doppler blood flow and vascular conductance in rat sciatic nerve and skeletal muscle.

  1997cites this paper
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  1996cites this paper
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  1995cites this paper
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  1995cites this paper
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  1995cites this paper
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  1995cites this paper
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  1995cites this paper
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  1995cites this paper
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  1995cites this paper
• Aldose reductase inhibition, nerve perfusion, oxygenation and function in streptozotocin-diabetic rats: Dose-response considerations and independence from a myo-inositol mechanism

  1994cites this paper
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  1994cites this paper
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  1994cites this paper
• The relationship of vascular changes to metabolic factors in diabetes mellitus and their role in the development of peripheral nerve complications.

  1994cites this paper
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  1994cites this paper
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  1994cites this paper