Participation of auto-anti-idiotypes in immune complex glomerulonephritis in rabbits.

We report the presence of auto-anti-Id antibodies in the glomerular immune deposits of a rabbit with chronic serum sickness induced by daily i.v. injections of bovine serum albumin. Auto-anti-Id antibodies were also documented in the serum of the same animal during the phase of chronic serum sickness in which immune complex glomerulonephritis develops. These results suggest that auto-anti-Id may normally participate in pathologic reactions and may be one of the mechanisms of potentiation and/or progression of immunopathologic lesions.

• Publication year

  1983

• Venue

  Journal of Immunology

• Publication date

  1983-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4049/jimmunol.131.6.2781PMID 6227667
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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