Bioinformatics-based searches for correlations between subcellular localization and pI or charge distribution of proteins have failed to detect meaningful correlations. Recent work published in BMC Biology finds that a physicochemical metric of charge distribution correlates better with subcellular pH than does pI. See research article http://www.biomedcentral.com/1741-7007/7/69
Adaptations of proteins to cellular and subcellular pH
Published 2009 in Journal of Biology
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- Publication year
2009
- Venue
Journal of Biology
- Publication date
2009-12-02
- Fields of study
Biology, Medicine, Chemistry
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Semantic Scholar, PubMed
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