CtIP-dependent DNA end resection, which was previously thought to be necessary for CHK1 kinase activation and subsequent DNA damage checkpoint induction, is in fact only required for sustained checkpoint signaling.
CtIP-dependent DNA resection is required for DNA damage checkpoint maintenance but not initiation
A. N. Kousholt,Kasper Fugger,Saskia Hoffmann,Brian D. Larsen,T. Menzel,A. Sartori,C. Sørensen
Published 2012 in Journal of Cell Biology
ABSTRACT
PUBLICATION RECORD
- Publication year
2012
- Venue
Journal of Cell Biology
- Publication date
2012-06-25
- Fields of study
Biology, Medicine
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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