Inflammation and Fibrosis in Perirenal Adipose Tissue of Patients With Aldosterone-Producing Adenoma

No abstract is available for this paper.

• Publication year

  2018

• Venue

  Endocrinology

• Publication date

  Unknown publication date

• Fields of study

  Medicine, Environmental Science

• Identifiers
  DOI 10.1210/en.2017-00651PMID 29059354
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Atrial fibrillation is associated with the fibrotic remodelling of adipose tissue in the subepicardium of human and sheep atria

  2017cited by this paper
• The cardiovascular markers copeptin and high-sensitive C-reactive protein decrease following specific therapy for primary aldosteronism

  2016cited by this paper
• The Management of Primary Aldosteronism: Case Detection, Diagnosis, and Treatment: An Endocrine Society Clinical Practice Guideline.

  2016influential reference
• Determination of UCP1 expression in subcutaneous and perirenal adipose tissues of patients with hypertension

  2015cited by this paper
• Increased prevalence of diabetes mellitus and the metabolic syndrome in patients with primary aldosteronism of the German Conn's Registry.

  2015cited by this paper
• Transcription Factor Egr1 is Involved in High Glucose-Induced Proliferation and Fibrosis in Rat Glomerular Mesangial Cells

  2015cited by this paper
• Progress in aldosteronism: a review of the prevalence of primary aldosteronism in pre-hypertension and hypertension.

  2015cited by this paper
• Human epicardial adipose tissue induces fibrosis of the atrial myocardium through the secretion of adipo-fibrokines.

  2015cited by this paper
• Hypertension Renin–Angiotensin–Aldosterone System Alterations

  2015cited by this paper
• MicroRNA‐455 regulates brown adipogenesis via a novel HIF1an‐AMPK‐PGC1α signaling network

  2015cited by this paper
• Omental adipose tissue fibrosis and insulin resistance in severe obesity

  2015cited by this paper
• Aldosterone Promotes Cardiac Endothelial Cell Proliferation In Vivo

  2015cited by this paper
• Human adipocyte function is impacted by mechanical cues

  2014cited by this paper
• Primary aldosteronism and essential hypertension: assessment of cardiovascular risk at diagnosis and after treatment.

  2014cited by this paper
• The DPP-4 inhibitor sitagliptin attenuates the progress of atherosclerosis in apolipoprotein-E-knockout mice via AMPK- and MAPK-dependent mechanisms

  2014cited by this paper
• Characterization of brown adipose tissue in the human perirenal depot

  2014cited by this paper
• Differentiation of Human Induced Pluripotent Stem Cells into Brown and White Adipocytes: Role of Pax3

  2014cited by this paper
• Mineralocorticoid receptor antagonism induces browning of white adipose tissue through impairment of autophagy and prevents adipocyte dysfunction in high‐fat‐diet‐fed mice

  2014cited by this paper
• Anatomical Localization, Gene Expression Profiling, and Functional Characterization of Adult Human Neck Brown Fat

  2013cited by this paper
• Aldosterone directly affects apelin expression and secretion in adipocytes.

  2013cited by this paper
• Fibrosis and adipose tissue dysfunction.

  2013cited by this paper
• Aldosterone, C-Reactive Protein, and Plasma B-Type Natriuretic Peptide Are Associated With the Development of Metabolic Syndrome and Longitudinal Changes in Metabolic Syndrome Components

  2013cited by this paper
• Endothelial mineralocorticoid receptor activation mediates endothelial dysfunction in diet-induced obesity

  2013cited by this paper
• Demonstration of Blood Pressure-Independent Noninfarct Myocardial Fibrosis in Primary Aldosteronism: A Cardiac Magnetic Resonance Imaging Study

  2012cited by this paper
• Aldosterone Perturbs Adiponectin and PAI-1 Expression and Secretion in 3T3-L1 Adipocytes

  2011cited by this paper
• Eplerenone in patients with systolic heart failure and mild symptoms.

  2011cited by this paper
• Antiadipogenic effects of the mineralocorticoid receptor antagonist drospirenone: potential implications for the treatment of metabolic syndrome.

  2010cited by this paper
• Analysis of insulin sensitivity in adipose tissue of patients with primary aldosteronism.

  2010cited by this paper
• Blockade of mineralocorticoid receptor reverses adipocyte dysfunction and insulin resistance in obese mice.

  2009cited by this paper
• Aldosterone inhibits insulin-induced glucose uptake by degradation of insulin receptor substrate (IRS) 1 and IRS2 via a reactive oxygen species-mediated pathway in 3T3-L1 adipocytes.

  2009cited by this paper
• The secretory function of adipocytes in the physiology of white adipose tissue

  2008cited by this paper
• Metabolic Dysregulation and Adipose Tissue Fibrosis: Role of Collagen VI

  2008cited by this paper
• Case detection, diagnosis, and treatment of patients with primary aldosteronism: an endocrine society clinical practice guideline.

  2008cited by this paper
• Mineralocorticoid Receptor Blockade Reverses Obesity-Related Changes in Expression of Adiponectin, Peroxisome Proliferator-Activated Receptor-&ggr;, and Proinflammatory Adipokines

  2008influential reference
• CCR2 modulates inflammatory and metabolic effects of high-fat feeding.

  2006cited by this paper
• Mechanisms for nongenomic and genomic effects of aldosterone on Na+/H+ exchange in vascular smooth muscle cells

  2005cited by this paper
• Participation of aldosterone in the vascular inflammatory response of spontaneously hypertensive rats: role of the NFκB/IκB system

  2005cited by this paper
• Evidence for an increased rate of cardiovascular events in patients with primary aldosteronism.

  2005cited by this paper
• Human Epicardial Adipose Tissue Is a Source of Inflammatory Mediators

  2003cited by this paper
• Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance.

  2003cited by this paper
• Obesity is associated with macrophage accumulation in adipose tissue.

  2003cited by this paper
• Essential Role of Insulin Receptor Substrate 1 in Differentiation of Brown Adipocytes

  2001cited by this paper
• Mineralocorticoid and glucocorticoid receptors inhibit UCP expression and function in brown adipocytes.

  2001cited by this paper
• The mineralocorticoid receptor mediates aldosterone-induced differentiation of T37i cells into brown adipocytes.

  2000cited by this paper
• β3-Adrenergic Stimulation Differentially Inhibits Insulin Signaling and Decreases Insulin-induced Glucose Uptake in Brown Adipocytes*

  1999cited by this paper
• Aldosterone stimulated differentiation of mouse 3T3-L1 cells into adipocytes.

  1993cited by this paper

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  2026cites this paper
• Salivary free aldosterone awakening response and cardiovascular risk in men with CHD, hypertension, and healthy controls

  2026cites this paper
• Assessment of MRI-Derived proton density fat fraction of total subcutaneous adipose tissue for discrimination primary aldosteronism subtypes

  2026cites this paper
• Adipose Tissue Signaling in Aldosterone-Producing Adenomas: Paracrine and Endocrine Effects.

  2025cites this paper
• Perinephric Myxoid Pseudotumor of Fat: A Series of 29 Cases Demonstrating Inconsistent Associations With Underlying Kidney Disease.

  2025cites this paper
• Unraveling the genetic basis of metabolic traits and benign adrenal tumors: a comprehensive causal analysis.

  2025cites this paper
• The Emerging Role of Aldosterone Synthase Inhibitors in Overcoming Renin–Angiotensin–Aldosterone System Therapy Limitations: A Narrative Review

  2025cites this paper
• Causal effects of primary aldosteronism on inflammation and bone density: evidence from Mendelian randomization, animal, and clinical studies

  2025cites this paper
• Perirenal Adipose Tissue and Hypertension: Observational and Genetic Analyses.

  2025cites this paper
• Ultrasound-Guided Radiofrequency Ablation for Unilateral Isolated Aldosterone-Producing Adenoma: A Two-centre Retrospective Study.

  2025cites this paper
• Adipose Composition Before and After Primary Aldosteronism Treatment Depends on Primary Aldosteronism Subtypes and Plasma Aldosterone Concentration Before the Treatment

  2025cites this paper
• Fat-cartilage axis: the regulation of IL-6/Osteopontin signaling in osteoarthritis of mice

  2025cites this paper
• MicroRNA-24-3p targeting Top1 in perirenal fat is involved in circulating inflammation and high cardiovascular disease risk in patients with primary aldosteronism

  2025cites this paper
• Browning of Aldosterone‐Producing Adenoma Adjacent Adipose Tissue Involved in Aldosterone Synthesis Regulation

  2025cites this paper
• Adrenal - adipose tissue crosstalk in health and disease.

  2025cites this paper
• Effects of perirenal fat accumulation on cardiometabolic and renal functions and mineralocorticoid receptor activation in primary aldosteronism

  2025cites this paper
• The role of perirenal adipose tissue deposition in chronic kidney disease progression: Mechanisms and therapeutic implications.

  2024cites this paper
• Myosteatosis and sarcopenia are linked to autonomous cortisol secretion in patients with aldosterone-producing adenomas

  2024cites this paper
• Epigenetic Regulation of the Renin–Angiotensin–Aldosterone System in Hypertension

  2024cites this paper
• Combination of ADAM17 knockdown with eplerenone is more effective than single therapy in ameliorating diabetic cardiomyopathy

  2024cites this paper
• Subtype-specific body composition and metabolic risk in patients with primary aldosteronism.

  2023cites this paper
• Cardiovascular Disease in Obstructive Sleep Apnea: Putative Contributions of Mineralocorticoid Receptors

  2023cites this paper
• Perirenal Fat Thickness is Associated with Metabolic Dysfunction-Associated Fatty Liver Disease in Type 2 Diabetes Mellitus

  2023cites this paper
• Enhanced Levels of Adiposity, Stretch and Fibrosis Markers in Patients with Coexistent Heart Failure and Atrial Fibrillation

  2023cites this paper
• Association Between Renal Sinus Fat and Cardiometabolic and Renin-Angiotensin System Parameters in Primary Aldosteronism

  2023cites this paper
• Aldosterone and Aldosterone Synthase Inhibitors in Cardiorenal Disease.

  2023cites this paper
• Epigenetic alterations of 11beta-hydroxysteroid dehydrogenase 1 gene in the adipose tissue of patients with primary aldosteronism.

  2023cites this paper
• Cerebro-Cardiovascular Risk, Target Organ Damage, and Treatment Outcomes in Primary Aldosteronism

  2022cites this paper
• Association of Aldosterone with Mortality in the General Population

  2022cites this paper
• Roles of lipid metabolism and its regulatory mechanism in idiopathic pulmonary fibrosis: A review.

  2022cites this paper
• Brown to White Fat Transition Overlap With Skeletal Muscle During Development of Larger Mammals: Is it a Coincidence?

  2022cites this paper
• Online prediction model for primary aldosteronism in patients with hypertension in Chinese population: A two-center retrospective study

  2022cites this paper
• Sex-specific Association of Primary Aldosteronism With Visceral Adiposity

  2022cites this paper
• Risk Factors Associated With Lower Bone Mineral Density in Primary Aldosteronism Patients

  2022cites this paper
• Perirenal Adipose Tissue Inflammation: Novel Insights Linking Metabolic Dysfunction to Renal Diseases

  2021cites this paper
• Evaluation of Abdominal Computed Tomography Scans for Differentiating the Discrepancies in Abdominal Adipose Tissue Between Two Major Subtypes of Primary Aldosteronism

  2021cites this paper
• Perirenal Adipose Tissue—Current Knowledge and Future Opportunities

  2021cites this paper
• Epicardial Adipose Tissue: From Cell to Clinic

  2020cites this paper
• Aldosterone, Inflammation, Immune System, and Hypertension

  2020cites this paper
• Metabolic Dysregulation in Idiopathic Pulmonary Fibrosis

  2020cites this paper
• Association of visceral adiposity and clinical outcome among patients with aldosterone producing adenoma

  2020cites this paper
• Characterization of the inflammatory‐metabolic phenotype of heart failure with a preserved ejection fraction: a hypothesis to explain influence of sex on the evolution and potential treatment of the disease

  2020cites this paper
• Exendin-4 Improves Diabetic Kidney Disease in C57BL/6 Mice Independent of Brown Adipose Tissue Activation

  2020cites this paper
• Adrenal Secretome and Epicardial Adipose Tissue

  2020cites this paper
• Increased oxidative stress, inflammation and fibrosis in perirenal adipose tissue of patients with cortisol-producing adenoma

  2019cites this paper
• MONOCYTE COUNT TO HDL-CHOLESTEROL RATIO MAY BE A NOVEL CARDIOMETABOLIC MARKER IN PATIENTS WITH FUNCTIONAL ADRENAL TUMORS

  2019cites this paper
• Paracrine Regulation of Aldosterone Secretion in Physiological and Pathophysiological Conditions.

  2019cites this paper
• Hypertension: Focus on autoimmunity and oxidative stress.

  2018cites this paper
• Epicardial Adipose Tissue May Mediate Deleterious Effects of Obesity and Inflammation on the Myocardium.

  2018cites this paper