Involvement of Estrone-3-Sulfate Transporters in Proliferation of Hormone-Dependent Breast Cancer Cells

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Journal of Pharmacology and Experimental Therapeutics

• Publication date

  2004-12-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1124/JPET.104.071522PMID 15328376
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Estrone sulfate: A potential source of estradiol in human breast cancer tissues

  2005cited by this paper
• Organic anion transporting polypeptides of the OATP/SLC21 family: phylogenetic classification as OATP/SLCO superfamily, new nomenclature and molecular/functional properties

  2004cited by this paper
• Involvement of organic anion transporting polypeptides in the transport of troglitazone sulfate: implications for understanding troglitazone hepatotoxicity.

  2004cited by this paper
• Functional Complementation between a Novel Mammalian Polygenic Transport Complex and an Evolutionarily Ancient Organic Solute Transporter, OSTα-OSTβ*

  2003cited by this paper
• Contribution of organic anion transporting polypeptide OATP‐C to hepatic elimination of the opioid pentapeptide analogue [d‐Ala 2 , d‐Leu5]‐enkephalin

  2003cited by this paper
• Identification of steroid sulfate transport processes in the human mammary gland.

  2003cited by this paper
• The superfamily of organic anion transporting polypeptides.

  2003cited by this paper
• Characterization of an organic anion-transporting polypeptide (OATP-B) in human placenta.

  2002cited by this paper
• In situ production of estrogens in human breast carcinoma

  2002cited by this paper
• Functional Characterization of Human Organic Anion Transporting Polypeptide B (OATP-B) in Comparison with Liver-Specific OATP-C

  2001cited by this paper
• Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family.

  2000cited by this paper
• Stimulation of MCF-7 breast cancer cell proliferation by estrone sulfate and dehydroepiandrosterone sulfate: inhibition by novel non-steroidal steroid sulfatase inhibitors.

  2000cited by this paper
• In‐vivo and In‐vitro Evidence of a Carrier‐mediated Efflux Transport System for Oestrone‐3‐sulphate across the Blood‐Cerebrospinal Fluid Barrier

  2000cited by this paper
• The multispecific organic anion transporter (OAT) family

  2000cited by this paper
• Molecular Cloning and Characterization of Multispecific Organic Anion Transporter 4 Expressed in the Placenta*

  2000cited by this paper
• Localization of estrone sulfatase in human breast carcinomas

  1999cited by this paper
• Lack of zonal uptake of estrone sulfate in enriched periportal and perivenous isolated rat hepatocytes.

  1999cited by this paper
• Molecular Cloning and Characterization of a New Multispecific Organic Anion Transporter from Rat Brain*

  1999cited by this paper
• Characterization of structural and functional properties of human 17 beta-hydroxysteroid dehydrogenase type 1 using recombinant enzymes and site-directed mutagenesis.

  1997cited by this paper
• Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta.

  1997cited by this paper
• Concentrations of estrone, estradiol and their sulfates, and evaluation of sulfatase and aromatase activities in patients with breast fibroadenoma

  1997cited by this paper
• Concentrations of estrone, estradiol, and estrone sulfate and evaluation of sulfatase and aromatase activities in pre- and postmenopausal breast cancer patients.

  1996cited by this paper
• Importance of estrogen sulfates in breast cancer.

  1989cited by this paper
• The hydrolysis of estrone sulfate and dehydroepiandrosterone sulfate by MCF-7 human breast cancer cells.

  1988cited by this paper
• Serum and urinary estrone sulfate during the menstrual cycle, measured by a direct radioimmunoassay, and fate of exogenously injected estrone sulfate.

  1987cited by this paper
• Enzymatic Control of Estrogen Production in Human Breast Cancer: Relative Significance of Aromatase versus Sulfatase Pathways

  1986cited by this paper
• Differential permeability of uterine and liver vascular beds to estrogens and estrogen conjugates.

  1984cited by this paper
• Biological significance of aromatase activity in human breast tumors.

  1983cited by this paper
• How effective is surgical adrenalectomy in lowering steroid hormone concentrations?

  1982cited by this paper
• Cancer of the breast: the past decade (second of two parts).

  1980cited by this paper
• Effects of plasma estrogen sulfates in mammary cancer cells.

  1980cited by this paper
• A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

  1976cited by this paper
• Estrone sulfate: production rate and metabolism in man.

  1972cited by this paper
• The characterization of estrone sulfate from human plasma.

  1961cited by this paper

• Dehydroepiandrosterone (DHEA) in relation to breast cancer.

  2025cites this paper
• Targeting Solute Carrier Transporters (SLCs) as a Therapeutic Target in Different Cancers

  2024cites this paper
• Role of the Sodium-Dependent Organic Anion Transporter (SOAT/SLC10A6) in Physiology and Pathophysiology

  2023cites this paper
• The Effects of Deoxyelephantopin on the Akt/mTOR/P70S6K Signaling Pathway in MCF-7 Breast Carcinoma Cells In Vitro

  2022cites this paper
• Functions of Dehydroepiandrosterone in Relation to Breast Cancer.

  2022cites this paper
• Analysis of estrogen metabolites in oral Leukoplakia and oral squamous cell carcinoma

  2021cites this paper
• Highly expressed SLCO1B3 inhibits the occurrence and development of breast cancer and can be used as a clinical indicator of prognosis

  2021cites this paper
• Selective antiproliferative effect of C-2 halogenated 13α-estrones on cells expressing Organic anion-transporting polypeptide 2B1 (OATP2B1).

  2021cites this paper
• Jadomycins: A potential chemotherapy for multi‐drug resistant metastatic breast cancer

  2021cites this paper
• Solute transporters and malignancy: establishing the role of uptake transporters in breast cancer and breast cancer metastasis

  2020cites this paper
• Identification of anticancer OATP2B1 substrates by an in vitro triple-fluorescence-based cytotoxicity screen

  2019cites this paper
• Relevance of Steroid Biosynthesis, Metabolism and Transport in Pathophysiology and Drug Discovery

  2019influential citation
• Towards the Integration of Metabolic Network Modelling and Machine Learning for the Routine Analysis of High-Throughput Patient Data

  2019cites this paper
• Organic Anion Transporting Polypeptides: Emerging Roles in Cancer Pharmacology

  2019influential citation
• Estrone-3-Sulfate Stimulates the Proliferation of T47D Breast Cancer Cells Stably Transfected With the Sodium-Dependent Organic Anion Transporter SOAT (SLC10A6)

  2018cites this paper
• Serum metabolomics in oral leukoplakia and oral squamous cell carcinoma

  2017cites this paper
• SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway

  2017cites this paper
• Organic Anion Transporting Polypeptides as Drug Targets

  2017cites this paper
• The N‐terminal region of organic anion transporting polypeptide 1B3 (OATP1B3) plays an essential role in regulating its plasma membrane trafficking

  2017cites this paper
• The role of organic anion transporting polypeptides in drug absorption, distribution, excretion and drug-drug interactions

  2017cites this paper
• Contribution of Organic Anion-Transporting Polypeptides 1A/1B to Doxorubicin Uptake and Clearance

  2017cites this paper
• Predicting liver toxicity on basis of transporter interaction profiles

  2016cites this paper
• Methodological considerations in estrogen assays of breast fluid and breast tissue.

  2015cites this paper
• Physicochemical properties of novel protein kinase inhibitors in relation to their substrate specificity for drug transporters

  2015cites this paper
• Organic anion transporting polypeptide 2B1 expression correlates with uptake of estrone-3-sulfate and cell proliferation in estrogen receptor-positive breast cancer cells.

  2015cites this paper
• Effect of DNA methylation profile on OATP3A1 and OATP4A1 transcript levels in colorectal cancer.

  2015cites this paper
• The Regulation of Steroid Action by Sulfation and Desulfation

  2015cites this paper
• Organic anion-transporting polypeptides: a novel approach for cancer therapy

  2014cites this paper
• Expression of membrane transporters and metabolic enzymes involved in estrone-3-sulphate disposition in human breast tumour tissues

  2014cites this paper
• Organic Anion Transporting Polypeptides: A Novel Molecular Target for Hormone Dependent Breast Cancers

  2014influential citation
• Putative roles of organic anion transporting polypeptides (OATPs) in cell survival and progression of human cancers.

  2014cites this paper
• Organic Anion Transporting Polypeptides Expressed in Pancreatic Cancer May Serve As Potential Diagnostic Markers and Therapeutic Targets for Early Stage Adenocarcinomas

  2013influential citation
• Effect of X-ray irradiation on expression of organic anion transporting polypeptides

  2013cites this paper
• A Putative Role of Organic Anion Transporting Polypeptides (Oatps) In Cell Survival of Hormone-Dependent Breast and Prostate Cancers

  2013cites this paper
• Genetic polymorphisms of OATP transporters and their impact on intestinal absorption and hepatic disposition of drugs.

  2012cites this paper
• Hormonal enzymatic systems in normal and cancerous human breast: control, prognostic factors, and clinical applications

  2012cites this paper
• Targeting Organic Anion Transporting Polypeptides in Cancer to Improve Diagnostics and Therapy

  2012influential citation
• The expression and function of organic anion transporting polypeptides in normal tissues and in cancer.

  2012influential citation
• 消化管トランスポ－タ－による医薬品の吸収促進

  2012cites this paper
• Differential Role of Organic Anion-Transporting Polypeptides in Estrone-3-Sulphate Uptake by Breast Epithelial Cells and Breast Cancer Cells

  2012cites this paper
• Enhanced expression of organic anion transporting polypeptides (OATPs) in androgen receptor-positive prostate cancer cells: possible role of OATP1A2 in adaptive cell growth under androgen-depleted conditions.

  2012cites this paper
• Uptake transporters of the human OATP family: molecular characteristics, substrates, their role in drug-drug interactions, and functional consequences of polymorphisms.

  2011cites this paper
• Solute carrier transporters as targets for drug delivery and pharmacological intervention for chemotherapy.

  2011cites this paper
• Vectorial transport of fexofenadine across Caco-2 cells: involvement of apical uptake and basolateral efflux transporters.

  2011cites this paper
• Expression and localization of the uptake transporters OATP2B1, OATP3A1 and OATP5A1 in non-malignant and malignant breast tissue

  2011cites this paper
• Polymorphisms of the nuclear receptor pregnane X receptor and organic anion transporter polypeptides 1A2, 1B1, 1B3, and 2B1 are not associated with breast cancer risk

  2010cites this paper
• Uptake transporter organic anion transporting polypeptide 1B3 contributes to the growth of estrogen-dependent breast cancer.

  2010cites this paper
• Altered expression of organic anion transporter polypeptide (OATP) genes in human breast carcinoma

  2008cites this paper
• Interplay between the nuclear receptor pregnane X receptor and the uptake transporter organic anion transporter polypeptide 1A2 selectively enhances estrogen effects in breast cancer.

  2008cites this paper
• Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin administration and high-fat diet on the body weight and hepatic estrogen metabolism in female C3H/HeN mice.

  2008cites this paper
• Xenobiotic transporters of the human organic anion transporting polypeptides (OATP) family

  2008cites this paper
• Is it necessary to control the level of estrogen receptor α and β activation in postmenopausal hormone replacement therapy in order to achieve the optimal outcome? (Review).

  2008cites this paper
• Overexpression of OATP1B3 confers apoptotic resistance in colon cancer.

  2008cites this paper
• Organic Anion–Transporting Polypeptides

  2006cites this paper
• Suppression of Cell Proliferation by Inhibition of Estrone-3-Sulfate Transporter in Estrogen-Dependent Breast Cancer Cells

  2005influential citation