WT1, WTX and CTNNB1 mutation analysis in 43 patients with sporadic Wilms' tumor.

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Oncology Report

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.3892/or.2012.2096PMID 23117548
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Wilms Tumor Overview

  2013cited by this paper
• Stratification of Wilms tumor by genetic and epigenetic analysis

  2012cited by this paper
• Different incidences of epigenetic but not genetic abnormalities between Wilms tumors in Japanese and Caucasian children

  2012cited by this paper
• Wilms' tumours: about tumour suppressor genes, an oncogene and a chameleon gene

  2011cited by this paper
• Two novel WTX mutations underscore the unpredictability of male survival in osteopathia striata with cranial sclerosis

  2011cited by this paper
• WT1 synonymous single nucleotide polymorphism rs16754 correlates with higher mRNA expression and predicts significantly improved outcome in favorable-risk pediatric acute myeloid leukemia: a report from the children's oncology group.

  2010cited by this paper
• The Predominant WT1 Isoform (+KTS) Encodes a DNA-Binding Protein Targeting the Planar Cell Polarity Gene Scribble in Renal Podocytes

  2010cited by this paper
• WTX mutations can occur both early and late in the pathogenesis of Wilms tumour

  2010cited by this paper
• Canonical WNT signalling determines lineage specificity in Wilms tumour

  2009cited by this paper
• WTX inactivation is a frequent, but late event in Wilms tumors without apparent clinical impact

  2009cited by this paper
• WNT/β‐catenin pathway activation in Wilms tumors: A unifying mechanism with multiple entries?

  2009influential reference
• Germline mutations in WTX cause a sclerosing skeletal dysplasia but do not predispose to tumorigenesis

  2009cited by this paper
• The tumor suppressor WTX shuttles to the nucleus and modulates WT1 activity

  2009cited by this paper
• Functional inactivation of the WTX gene is not a frequent event in Wilms’ tumors

  2008cited by this paper
• Wilms tumor suppressor WTX negatively regulates WNT/β-catenin signaling

  2008cited by this paper
• Wilms tumor genetics: Mutations in WT1, WTX, and CTNNB1 account for only about one‐third of tumors

  2008cited by this paper
• Clinical relevance of mutations in the Wilms tumor suppressor 1 gene WT1 and the cadherin‐associated protein β1 gene CTNNB1 for patients with Wilms tumors

  2008cited by this paper
• Wilms Tumor Suppressor WTX Negatively Regulates WNT/ß-Catenin Signaling

  2007cited by this paper
• An X Chromosome Gene, WTX, Is Commonly Inactivated in Wilms Tumor

  2007influential reference
• Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling.

  2007cited by this paper
• Allelic imbalance in gene expression as a guide to cis-acting regulatory single nucleotide polymorphisms in cancer cells

  2007cited by this paper
• Different CTNNB1 mutations as molecular genetic proof for the independent origin of four Wilms tumours in a patient with a novel germ line WT1 mutation

  2007cited by this paper
• Wnt/beta-catenin signaling in development and disease.

  2006cited by this paper
• Plakoglobin (γ-catenin) has TCF/LEF family-dependent transcriptional activity in β-catenin-deficient cell line

  2004cited by this paper
• Twenty‐four new cases of WT1 germline mutations and review of the literature: Genotype/phenotype correlations for Wilms tumor development

  2004cited by this paper
• CTNNB1 mutations and overexpression of Wnt/beta-catenin target genes in WT1-mutant Wilms' tumors.

  2004cited by this paper
• Plakoglobin (gamma-catenin) has TCF/LEF family-dependent transcriptional activity in beta-catenin-deficient cell line.

  2004cited by this paper
• Regulation of E-cadherin expression and beta-catenin/Tcf transcriptional activity by the integrin-linked kinase.

  2004cited by this paper
• Frequency and heritability of WT1 mutations in nonsyndromic Wilms' tumor patients: a UK Children's Cancer Study Group Study.

  2004cited by this paper
• Plakoglobin (γ-catenin) has TCF/LEF family-dependent transcriptional activity in β-catenin-deficient cell line

  2004cited by this paper
• Correlation between a specific Wilms tumour suppressor gene (WT1) mutation and the histological findings in Wilms tumour (WT)

  2002cited by this paper
• Molecular Cloning: A Laboratory Manual

  2001cited by this paper
• Frequent association of beta-catenin and WT1 mutations in Wilms tumors.

  2000cited by this paper
• Frequent Association of β-Catenin and WT1 Mutations in Wilms Tumors

  2000cited by this paper
• Mutational activation of the beta-catenin proto-oncogene is a common event in the development of Wilms' tumors.

  1999influential reference
• Exon 9 mutations in the WT1 gene, without influencing KTS splice isoforms, are also responsible for Frasier syndrome

  1999cited by this paper
• Correlation of germ-line mutations and two-hit inactivation of the WT1 gene with Wilms tumors of stromal-predominant histology.

  1997cited by this paper
• RNA Processing: Wilms' tumour — the splicing connection?

  1995cited by this paper
• Evidence that WT1 mutations in Denys-Drash syndrome patients may act in a dominant-negative fashion.

  1993cited by this paper
• Zinc finger point mutations within the WT1 gene in Wilms tumor patients.

  1992cited by this paper
• Alternative splicing and genomic structure of the Wilms tumor gene WT1.

  1991cited by this paper
• Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome.

  1991cited by this paper
• A simple salting out procedure for extracting DNA from human nucleated cells.

  1988cited by this paper

• Calcifying nested stromal-epithelial tumor of the liver: Report of two cases revealing novel WT1 mutation and distinct epigenetic features.

  2025cites this paper
• Wilms Tumor in Children With AMER1/WTX Germline Pathogenic Variants: A Multicenter Case Series

  2025cites this paper
• Novel Variants of IGF2 Gene Are Linked With Neural Tube Defects‐An In Silico to Clinical Approach in West Bengal, India

  2025cites this paper
• Inter-Ethnic Variations in the Clinical, Pathological, and Molecular Characteristics of Wilms Tumor

  2024cites this paper
• Cancer predisposition signaling in Beckwith-Wiedemann Syndrome drives Wilms tumor development

  2023cites this paper
• The function of miR-145 in colorectal cancer progression; an updated review on related signaling pathways.

  2022cites this paper
• Whole exome sequencing identified a rare WT1 loss‐of‐function variant in a non‐syndromic POI patient

  2021cites this paper
• New mutation in WT1 gene in a boy with an incomplete form of Denys-Drash syndrome

  2021cites this paper
• Mir-20a-5p induced WTX deficiency promotes gastric cancer progressions through regulating PI3K/AKT signaling pathway

  2020cites this paper
• The association of miR34b/c and TP53 gene polymorphisms with Wilms tumor risk in Chinese children

  2020cites this paper
• RETRACTED ARTICLE: Mir20a/106a-WTX axis regulates RhoGDIa/CDC42 signaling and colon cancer progression

  2019cites this paper
• Wilms' Tumor Protein 1 and Enzymatic Oxidation of 5-Methylcytosine in Brain Tumors: Potential Perspectives

  2018cites this paper
• Coexistence of synchronous bilateral Wilms tumor and trisomy 21 – first report and review of literature

  2018cites this paper
• MicroRNA-613 attenuates the proliferation, migration and invasion of Wilms' tumor via targeting FRS2.

  2017cites this paper
• Clinical, Pathologic, and Genetic Features of Wilms Tumors With WTX Gene Mutation

  2017cites this paper
• Étude des « Topologically Associated Domains (TADs) » dans les anomalies du développement

  2017cites this paper
• Clinical, pathologic, and genetic features of Wilms tumors with WTX gene mutation.

  2016cites this paper
• Activation of the Wnt/β-catenin pathway is common in wilms tumor, but rarely through β-catenin mutation and APC promoter methylation

  2016cites this paper
• Genetic variation frequencies in Wilms' tumor: A meta‐analysis and systematic review

  2016cites this paper
• Array CGH Analysis of Paired Blood and Tumor Samples from Patients with Sporadic Wilms Tumor

  2015cites this paper
• Clinical next generation sequencing of pediatric-type malignancies in adult patients identifies novel somatic aberrations

  2015cites this paper
• Analyzing the gene expression profile of anaplastic histology Wilms’ tumor with real-time polymerase chain reaction arrays

  2015cites this paper
• Association of TP53 polymorphisms on the risk of Wilms tumor

  2014cites this paper