Clinical significance of Smac/DIABLO expression in colorectal cancer.

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Oncology Report

• Publication date

  Unknown publication date

• Fields of study

  Medicine

• Identifiers
  DOI 10.3892/OR_00000229PMID 19148507
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Modification of gene products involved in resistance to apoptosis in metastatic colon cancer cells: roles of Fas, Apaf-1, NFkappaB, IAPs, Smac/DIABLO, and AIF.

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• Transfection of Smac sensitizes tumor cells to etoposide-induced apoptosis and eradicates established human hepatoma in vivo

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• Mitochondria as therapeutic targets for cancer chemotherapy

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• Relationship between expression of Smac and Survivin and apoptosis of primary hepatocellular carcinoma.

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• Altered expression of c-IAP1, survivin, and Smac contributes to chemotherapy resistance in thyroid cancer cells.

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• Expression of Smac/DIABLO in B-cell non-Hodgkin and Hodgkin lymphomas.

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  2005cited by this paper
• Downregulation of Smac/DIABLO expression in renal cell carcinoma and its prognostic significance.

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  2005cited by this paper
• Stable transfection of extrinsic Smac gene enhances apoptosis-inducing effects of chemotherapeutic drugs on gastric cancer cells.

  2005cited by this paper
• Expression of Smac/DIABLO is a novel prognostic marker in lung cancer.

  2004cited by this paper
• Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand–Induced Apoptosis Is Inhibited by Bcl-2 but Restored by the Small Molecule Bcl-2 Inhibitor, HA 14-1, in Human Colon Cancer Cells

  2004cited by this paper
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  2004cited by this paper
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  2004cited by this paper
• Elevated expression of inhibitor of apoptosis proteins in prostate cancer.

  2003cited by this paper
• Apoptosis regulators.

  2003cited by this paper
• Identification of Omi/HtrA2 as a Mitochondrial Apoptotic Serine Protease That Disrupts Inhibitor of Apoptosis Protein-Caspase Interaction*

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• Cell death inhibition: keeping caspases in check.

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• Mitochondrial endonuclease G is important for apoptosis in C. elegans

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• Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition.

  2000cited by this paper
• Expression and prognostic significance of IAP-family genes in human cancers and myeloid leukemias.

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  1999cited by this paper
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  1983cited by this paper

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• Smac/DIABLO protein acts as an independent prognostic factor in oral squamous cell carcinoma

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• A Review of the Current Impact of Inhibitors of Apoptosis Proteins and Their Repression in Cancer

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• Curcumin analog, GO-Y078, induces HO-1 transactivation-mediated apoptotic cell death of oral cancer cells by triggering MAPK pathways and AP-1 DNA-binding activity

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• Low expression of pro-apoptotic proteins Bax, Bak and Smac indicates prolonged progression-free survival in chemotherapy-treated metastatic melanoma

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  2016cites this paper
• Effect of Smac in combination with cisplatin on esophageal cancer cell line ECA109.

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  2015cites this paper
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  2014influential citation
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• Role of Apoptosis in Colon Cancer Biology, Therapy, and Prevention

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