IGF-II/mannose 6-phosphate receptor activation induces metalloproteinase-9 matrix activity and increases plasminogen activator expression in H9c2 cardiomyoblast cells.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Journal of Molecular Endocrinology

• Publication date

  2008-08-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1677/JME-08-0051PMID 18495691
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• ECM remodeling in hypertensive heart disease.

  2007cited by this paper
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  2007cited by this paper
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  2006influential reference
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  2004cited by this paper
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  2004cited by this paper
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  2003cited by this paper
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  2002cited by this paper
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  2002cited by this paper
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  2000cited by this paper
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  2000influential reference
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  1999cited by this paper
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  1998cited by this paper
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