LncRNA UCA1 attenuates autophagy-dependent cell death through blocking autophagic flux under arsenic stress.

No abstract is available for this paper.

• Publication year

  2018

• Venue

  Toxicology Letters

• Publication date

  2018-03-01

• Fields of study

  Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1016/j.toxlet.2017.12.009PMID 29248574
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Artesunate suppresses the viability and mobility of prostate cancer cells through UCA1, the sponge of miR-184

  2017cited by this paper
• Nrf-2-driven long noncoding RNA ODRUL contributes to modulating silver nanoparticle-induced effects on erythroid cells.

  2017cited by this paper
• Role of OSGIN1 in mediating smoking-induced autophagy in the human airway epithelium

  2017cited by this paper
• LincRNA‐p21 knockdown enhances radiosensitivity of hypoxic tumor cells by reducing autophagy through HIF‐1/Akt/mTOR/P70S6K pathway

  2017cited by this paper
• LncRNA UCA1 in anti-cancer drug resistance

  2017cited by this paper
• lncRNA UCA1 Contributes to Imatinib Resistance by Acting as a ceRNA Against miR-16 in Chronic Myeloid Leukemia Cells

  2017cited by this paper
• The long noncoding RNA HOTAIR activates autophagy by upregulating ATG3 and ATG7 in hepatocellular carcinoma.

  2016cited by this paper
• miR-214 protects erythroid cells against oxidative stress by targeting ATF4 and EZH2.

  2016cited by this paper
• Long non-coding RNA HNF1A-AS1 functioned as an oncogene and autophagy promoter in hepatocellular carcinoma through sponging hsa-miR-30b-5p.

  2016cited by this paper
• Identification of long-non coding RNA UCA1 as an oncogene in renal cell carcinoma.

  2016cited by this paper
• Mechanisms of long noncoding RNA function in development and disease

  2016cited by this paper
• Pseudogenes regulate parental gene expression via ceRNA network

  2016cited by this paper
• Metabolism and toxicity of arsenicals in mammals.

  2016cited by this paper
• Stressing out over long noncoding RNA.

  2016cited by this paper
• Non-coding RNAs as orchestrators of autophagic processes.

  2016cited by this paper
• The roles of mitochondria in radiation-induced autophagic cell death in cervical cancer cells

  2016cited by this paper
• Competing endogenous RNA networks and gastric cancer.

  2015cited by this paper
• Role of autophagy in arsenite-induced neurotoxicity: the involvement of α-synuclein.

  2015cited by this paper
• Raloxifene induces autophagy-dependent cell death in breast cancer cells via the activation of AMP-activated protein kinase.

  2015cited by this paper
• mTOR: a pharmacologic target for autophagy regulation.

  2015cited by this paper
• Basic biology and therapeutic implications of lncRNA.

  2015cited by this paper
• Transcriptional and epigenetic regulation of autophagy in aging

  2015cited by this paper
• Arsenic cardiotoxicity: An overview.

  2015cited by this paper
• Long Non-Coding RNA Urothelial Carcinoma Associated 1 (UCA1): Insight into Its Role in Human Diseases.

  2015cited by this paper
• APF lncRNA regulates autophagy and myocardial infarction by targeting miR-188-3p

  2015cited by this paper
• Epigenetic modifications as regulatory elements of autophagy in cancer.

  2015cited by this paper
• ceRNA in cancer: possible functions and clinical implications

  2015cited by this paper
• MicroRNA-216b/Beclin 1 axis regulates autophagy and apoptosis in human Tenon's capsule fibroblasts upon hydroxycamptothecin exposure.

  2014cited by this paper
• Autosis and autophagic cell death: the dark side of autophagy

  2014cited by this paper
• Competing Endogenous RNA: The Key to Posttranscriptional Regulation

  2014cited by this paper
• Sodium arsenite induces ROS-dependent autophagic cell death in pancreatic β-cells.

  2014cited by this paper
• Autophagic Cell Death and Cancer

  2014cited by this paper
• Hypoxia Induces Autophagic Cell Death through Hypoxia-Inducible Factor 1α in Microglia

  2014cited by this paper
• Long noncoding RNA in liver diseases

  2014cited by this paper
• Health Effects of Chronic Arsenic Exposure

  2014cited by this paper
• Histone deacetylase 4 selectively contributes to podocyte injury in diabetic nephropathy.

  2014cited by this paper
• Genotoxic and epigenetic mechanisms in arsenic carcinogenicity

  2014cited by this paper
• Molecular mechanisms of mTOR regulation by stress

  2014cited by this paper
• Lapatinib induces autophagic cell death and inhibits growth of human hepatocellular carcinoma

  2014cited by this paper
• Posttranscriptional gene regulation by long noncoding RNA.

  2013cited by this paper
• Groundwater Arsenic Contamination Throughout China

  2013cited by this paper
• Guidelines for the use and interpretation of assays for monitoring autophagy

  2012cited by this paper
• mTOR-dependent cell survival mechanisms.

  2012cited by this paper
• S100A8-targeting siRNA enhances arsenic trioxide-induced myeloid leukemia cell death by down-regulating autophagy.

  2011cited by this paper
• Arsenic-induced oxidative stress and its reversibility.

  2011cited by this paper
• Arsenic: toxicity, oxidative stress and human disease

  2011cited by this paper
• Regulation of mammalian autophagy in physiology and pathophysiology.

  2010cited by this paper
• Autophagy and the integrated stress response.

  2010cited by this paper
• An Emerging Role for Epigenetic Dysregulation in Arsenic Toxicity and Carcinogenesis

  2010cited by this paper
• mTOR regulation of autophagy

  2010cited by this paper
• Monitoring autophagic degradation of p62/SQSTM1.

  2009cited by this paper
• Autophagy fights disease through cellular self-digestion

  2008cited by this paper
• Autophagy: process and function.

  2007cited by this paper
• Arsenic trioxide induces autophagic cell death in malignant glioma cells by upregulation of mitochondrial cell death protein BNIP3

  2005cited by this paper
• Induction of autophagic cell death in malignant glioma cells by arsenic trioxide.

  2003cited by this paper

• Epigenetic Control of Redox Pathways in Cancer Progression

  2025cites this paper
• Therapeutic implication of oxidative stress-induced growth inhibitor 1 (OSGIN1) in cancer

  2025cites this paper
• miR-184 in hepatocellular carcinoma: a promising therapeutic target

  2025cites this paper
• LPS pretreated dental follicle stem cell derived exosomes promote periodontal tissue regeneration via miR-184 and PPARα-Akt-JNK signaling pathway

  2025cites this paper
• Exploring the biological functions and disease implications of OSGINs: A journey from discovery to clinical relevance.

  2025cites this paper
• Interplay between LncRNAs and autophagy-related pathways in leukemia: mechanisms and clinical implications

  2025cites this paper
• Inorganic arsenic modulates cell apoptosis by regulating Argonaute 2 expression via the p53 pathway.

  2025cites this paper
• OSGIN1 regulates PM2.5-induced fibrosis via mediating autophagy in an in vitro model of COPD.

  2024cites this paper
• Navigating the autophagic landscape: Epigenetic modulation in gastrointestinal cancer

  2024cites this paper
• Long non-coding RNAs regulate heavy metal-induced apoptosis in embryo-derived cells.

  2023cites this paper
• Inorganic arsenic-mediated upregulation of TUG1 promotes apoptosis in human bronchial epithelial cells by activating the p53 signaling pathway

  2023cites this paper
• Potential of oligonucleotide- and protein/peptide-based therapeutics in the management of toxicant/stressor-induced diseases

  2023cites this paper
• Arsenic and Human Health: New Molecular Mechanisms For Arsenic-Induced Cancers

  2023cites this paper
• Non-coding RNA therapeutics: Towards a new candidate for arsenic-induced liver disease.

  2023cites this paper
• Epigenotoxicity: a danger to the future life

  2023cites this paper
• Oxidative Stress-Induced Growth Inhibitor (OSGIN1), a Target of X-Box-Binding Protein 1, Protects Palmitic Acid-Induced Vascular Lipotoxicity through Maintaining Autophagy

  2022cites this paper
• Epigenetic regulation of autophagy in gastrointestinal cancers.

  2022cites this paper
• Role of autophagy and transcriptome regulation in acute brain injury.

  2022cites this paper
• Heavy Metal and Metalloid - Induced Reproductive Toxicity.

  2022cites this paper
• Regulation of pleiotropic physiological roles of nitric oxide signaling.

  2022cites this paper
• Activation of Pancreatic Acinar FXR Protects against Pancreatitis via Osgin1-Mediated Restoration of Efficient Autophagy

  2022cites this paper
• LncRNA OIP5-AS1 inhibits ferroptosis in prostate cancer with long-term cadmium exposure through miR-128-3p/SLC7A11 signaling.

  2021cites this paper
• Exploring the role of non-coding RNAs in autophagy

  2021cites this paper
• Transfer of lncRNA UCA1 by hUCMSCs-derived exosomes protects against hypoxia/reoxygenation injury through impairing miR-143-targeted degradation of Bcl-2

  2021cites this paper
• Long non-coding RNA DICER1-AS1-low expression in arsenic-treated A549 cells inhibits cell proliferation by regulating the cell cycle pathway.

  2021cites this paper
• METTL3 regulates PM2.5-induced cell injury by targeting OSGIN1 in human airway epithelial cells.

  2021cites this paper
• Comparative transcriptome analysis reveals the differential response to cadmium stress of two Pleurotus fungi: Pleurotus cornucopiae and Pleurotus ostreatus.

  2021cites this paper
• Dysregulation of autophagy acts as a pathogenic mechanism of non-alcoholic fatty liver disease (NAFLD) induced by common environmental pollutants.

  2021cites this paper
• Long Noncoding RNA UCA1 in Gastrointestinal Cancers: Molecular Regulatory Roles and Patterns, Mechanisms, and Interactions

  2021cites this paper
• LncRNA PCA3 promotes antimony-induced lipid metabolic disorder in prostate cancer by targeting MIR-132-3 P/SREBP1 signaling.

  2021cites this paper
• Role of Nitric Oxide in Gene Expression Regulation during Cancer: Epigenetic Modifications and Non-Coding RNAs

  2021cites this paper
• CircRNA-IGLL1/miR-15a/RNF43 axis mediates ammonia-induced autophagy in broilers jejunum via Wnt/β-catenin pathway.

  2021cites this paper
• Research progress of long non ⁃ coding RNA involved in arsenic toxicity

  2020cites this paper
• Targeting the miR-122/PKM2 autophagy axis relieves arsenic stress.

  2020cites this paper
• Arsenic-induced autophagy regulates apoptosis in AML-12 cells.

  2020cites this paper
• lncRNA OTUD6B-AS1 Exacerbates As2O3-Induced Oxidative Damage in Bladder Cancer via miR-6734-5p-Mediated Functional Inhibition of IDH2

  2020cites this paper
• The mechanisms of arsenic-induced ovotoxicity, ultrastructural alterations, and autophagic related paths: An enduring developmental study in folliculogenesis of mice.

  2020cites this paper
• Role of non-coding-RNAs in response to environmental stressors and consequences on human health

  2020cites this paper
• Current mechanistic perspectives on male reproductive toxicity induced by heavy metals.

  2020cites this paper
• Non-coding RNAs are involved in the response to oxidative stress.

  2020cites this paper
• When Oxidative Stress Meets Epigenetics: Implications in Cancer Development

  2020cites this paper
• LncRNA UCA1 Antagonizes Arsenic‐Induced Cell Cycle Arrest through Destabilizing EZH2 and Facilitating NFATc2 Expression

  2020cites this paper
• Long non‐coding RNA UCA1 promotes autophagy by targeting miR‐96‐5p in acute myeloid leukaemia

  2020cites this paper
• Double-edged effects of noncoding RNAs in responses to environmental genotoxic insults: Perspectives with regards to molecule-ecology network.

  2019cites this paper
• Arsenite exposure suppresses adipogenesis, mitochondrial biogenesis and thermogenesis via autophagy inhibition in brown adipose tissue

  2019cites this paper
• Competing Endogenous RNA and Coexpression Network Analysis for Identification of Potential Biomarkers and Therapeutics in association with Metastasis Risk and Progression of Prostate Cancer

  2019cites this paper
• Paternal exposure to arsenic resulted in oxidative stress, autophagy, and mitochondrial impairments in the HPG-S axis of pubertal male offspring.

  2019cites this paper
• Downregulation of lncRNA UCA1 ameliorates the damage of dopaminergic neurons, reduces oxidative stress and inflammation in Parkinson's disease through the inhibition of the PI3K/Akt signaling pathway.

  2019cites this paper
• LncRNA PU.1 AS regulates arsenic-induced lipid metabolism through EZH2/Sirt6/SREBP-1c pathway.

  2019cites this paper
• Occurrence of trace metals in foodstuffs and their health impact

  2018cites this paper