Histone H3 Lysine 4 Trimethylation, Lysine 27 Trimethylation, and Lysine 27 Acetylation Contribute to the Transcriptional Repression of Solute Carrier Family 47 Member 2 in Renal Cell Carcinoma

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Drug Metabolism And Disposition

• Publication date

  2017-01-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1124/dmd.116.073734PMID 27821436
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2011cited by this paper
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  2008cited by this paper
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  2008cited by this paper
• Renal cell carcinoma guideline.

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  2001cited by this paper

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