Polymorphism rs2476601 in the PTPN22 gene is associated with type 1 diabetes in children from the South Region of Brazil.

No abstract is available for this paper.

• Publication year

  2018

• Venue

  Gene

• Publication date

  2018-02-02

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.gene.2018.01.073PMID 29408732
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• PTPN22 Single-Nucleotide Polymorphisms in Iranian Patients with Type 1 Diabetes Mellitus

  2017cited by this paper
• PTPN22 and islet-specific autoimmunity: What have the mouse models taught us?

  2017cited by this paper
• 2. Classification and Diagnosis of Diabetes.

  2017cited by this paper
• The association of PTPN22 (rs2476601) and IL2RA (rs11594656) polymorphisms with T1D in Egyptian children.

  2016cited by this paper
• Superresolution imaging of the cytoplasmic phosphatase PTPN22 links integrin-mediated T cell adhesion with autoimmunity

  2016cited by this paper
• Association of TNF-α, CTLA4, and PTPN22 polymorphisms with type 1 diabetes and other autoimmune diseases in Brazil.

  2015cited by this paper
• Association analysis of PTPN22, CTLA4 and IFIH1 genes with type 1 diabetes in Colombian families在哥伦比亚家族中进行的PTPN22、CTLA4以及IFIH1基因与1型糖尿病的相关性分析

  2015cited by this paper
• PTPN22 Silencing in the NOD Model Indicates the Type 1 Diabetes–Associated Allele Is Not a Loss-of-Function Variant

  2013cited by this paper
• HLA-DR, HLA-DQB1 and PTPN22 gene polymorphism: association with age at onset for autoimmune diabetes

  2012cited by this paper
• LADA and T1D in Estonian population - two different genetic risk profiles.

  2012cited by this paper
• The −1123G>C Variant of PTPN22 Gene Promoter is Associated with Latent Autoimmune Diabetes in Adult Chinese Hans

  2012cited by this paper
• Meta-analysis of the family-based association between the PTPN22 C1858T polymorphism and Type 1 diabetes

  2012cited by this paper
• The autoimmune disease–associated PTPN22 variant promotes calpain-mediated Lyp/Pep degradation associated with lymphocyte and dendritic cell hyperresponsiveness

  2011cited by this paper
• Lymphoid tyrosine phosphatase and autoimmunity: human genetics rediscovers tyrosine phosphatases

  2010cited by this paper
• Autoimmune-associated PTPN22 R620W Variation Reduces Phosphorylation of Lymphoid Phosphatase on an Inhibitory Tyrosine Residue*

  2010cited by this paper
• The Protein Tyrosine Phosphatase Non-Receptor Type 22 C1858T Polymorphism Is a Joint Susceptibility Locus for Immunthyroiditis and Autoimmune Diabetes

  2009cited by this paper
• PTPN22 Deficiency Cooperates with the CD45 E613R Allele to Break Tolerance on a Non-Autoimmune Background1

  2009cited by this paper
• Testing for linkage and association with rheumatoid arthritis a ptpn22 promoter polymorphism reported to be associated and linked with type 1 diabetes in the Caucasian population

  2008cited by this paper
• The Protein Tyrosine Phosphatase Nonreceptor 22 (PTPN22) Is Associated With High GAD Antibody Titer in Latent Autoimmune Diabetes in Adults

  2007cited by this paper
• Genetic Variation in PTPN22 Corresponds to Altered Function of T and B Lymphocytes1

  2007cited by this paper
• Role of PTPN22 in type 1 diabetes and other autoimmune diseases.

  2006cited by this paper
• Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant

  2005cited by this paper
• PEST Domain-Enriched Tyrosine Phosphatase (PEP) Regulation of Effector/Memory T Cells

  2004cited by this paper
• The role of T-cells in the pathogenesis of Type 1 diabetes: From cause to cure

  2003cited by this paper
• Cooperative Inhibition of  T-Cell Antigen Receptor Signaling by a Complex between a Kinase and a Phosphatase

  1999cited by this paper
• Anergic self-reactive B cells present self antigen and respond normally to CD40-dependent T-cell signals but are defective in antigen-receptor-mediated functions.

  1994cited by this paper

• The Relationship between T1DM and the Polymorphisms of IL2RA (Rs2104286) and PTPN22 (Rs2476601) Genes among Children

  2023cites this paper
• GENETIC ASSOCIATION OF PTPN22 POLYMORPHISMS WITH TYPE 1 DIABETES IN PAKISTANI CHILDREN

  2023cites this paper
• The IL18 rs1946518 and PTPN22 rs2476601 polymorphisms are not associated with adult- and childhood-onset type 1 diabetes mellitus

  2020cites this paper
• LCK rs10914542-G allele associates with type 1 diabetes in children via T cell hyporesponsiveness

  2019cites this paper
• Association of protein tyrosine phosphatase non-receptor type 22 gene functional variant C1858T, HLA-DQ/DR genotypes and autoantibodies with susceptibility to type-1 diabetes mellitus in Kuwaiti Arabs

  2018cites this paper
• PTPN22 interacts with EB1 to regulate T cell receptor signaling

  2018cites this paper