The efficiency of clinical trial designs for predictive biomarker validation

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Clinical Trials

• Publication date

  2010-06-22

• Fields of study

  Medicine

• Identifiers
  DOI 10.1177/1740774510370497PMID 20571132
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Predictive Biomarkers in the Development of Oncology Drugs: A Therapeutic Industry Perspective

  2009cited by this paper
• Biomarker as a classifier in pharmacogenomics clinical trials: a tribute to 30th anniversary of PSI

  2007cited by this paper
• Approaches to evaluation of treatment effect in randomized clinical trials with genomic subset

  2007cited by this paper
• Gene expression profiling of ATP-binding cassette (ABC) transporters as a predictor of the pathologic response to neoadjuvant chemotherapy in breast cancer patients

  2006cited by this paper
• Clinical Trial Designs for Prospective Validation of Biomarkers

  2005cited by this paper
• Clinical trial designs for predictive marker validation in cancer treatment trials.

  2005influential reference
• On the efficiency of targeted clinical trials

  2005cited by this paper
• Challenges for Biomarkers in Cancer Detection

  2004cited by this paper
• Issues and barriers to development of clinically useful tumor markers: a development pathway proposal.

  2002cited by this paper
• Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

  2001cited by this paper
• The n e w e n g l a n d j o u r n a l of m e d i c i n e

  2001cited by this paper
• Nonparametrics: Statistical Methods Based on Ranks

  1979cited by this paper

• Two-stage stratified designs with survival outcomes and adjustment for misclassification in predictive biomarkers

  2024cites this paper
• Randomized test-treatment studies with an outlook on adaptive designs

  2021cites this paper
• An alternative method to analyse the biomarker‐strategy design

  2018cites this paper
• Efficiency of Enrichment Design for Pre–Post Trials with Binary Endpoint

  2018cites this paper
• Relative efficiency of precision medicine designs for clinical trials with predictive biomarkers

  2018cites this paper
• Biomarker-Guided Non-Adaptive Trial Designs in Phase II and Phase III: A Methodological Review

  2017influential citation
• On study designs and hypotheses for clinical trials with predictive biomarkers.

  2017cites this paper
• Biomarker-Guided Adaptive Trial Designs in Phase II and Phase III: A Methodological Review

  2016cites this paper
• Intégration des facteurs prédictifs de l'effet d'un traitement dans la conception et l'analyse des essais cliniques de petite taille : application à la maladie de Huntington.

  2016cites this paper
• Statistical innovations in diagnostic device evaluation

  2016cites this paper
• Novel method to analyse the Biomarker-strategy design

  2016cites this paper
• The impact of companion diagnostic device measurement performance on clinical validation of personalized medicine

  2015cites this paper
• Evaluation and validation of social and psychological markers in randomised trials of complex interventions in mental health: a methodological research programme.

  2015cites this paper
• Trial Designs for Personalizing Cancer Care: A Systematic Review and Classification

  2013cites this paper
• A general framework of marker design with optimal allocation to assess clinical utility

  2013cites this paper
• Integrating biomarker information within trials to evaluate treatment mechanisms and efficacy for personalised medicine

  2013cites this paper
• Evaluating Putative Predictive Biomarkers in Randomized Clinical Trials

  2012cites this paper
• Predictive biomarkers in colorectal cancer: usage, validation, and design in clinical trials

  2012cites this paper
• Study Designs and Statistical Analyses for Biomarker Research

  2012cites this paper
• BATE curve in assessment of clinical utility of predictive biomarkers

  2012cites this paper
• Pharmacogenetics: practices and opportunities for study design and data analysis.

  2011cites this paper
• Pediatric acute leukemia therapies informed by molecular analysis of high-risk disease.

  2011cites this paper
• Integrating biomarkers in clinical trials

  2011cites this paper