Proliferating Trichilemmal Tumor of Scalp: Benign or Malignant, A Dilemma

Reena Sharma,P. Verma,P. Yadav,Sonal Sharma

Published 2012 in Journal of Cutaneous and Aesthetic Surgery

ABSTRACT

PXE is a genetic disorder primarily affecting the skin, eyes and cardiovascular system, resulting from the accumulation of morphologically abnormal and mineralized elastic fibers in these tissues. The skin changes are often detected during childhood or adolescence and progress slowly and unpredictably during adulthood. The accumulation of abnormal calcified elastic fibers in the mid-dermis produces typical skin lesions, which consist of yellowish papules and plaques, and laxity with loss of elasticity. These lesions are primarily seen on the neck, axilla, antecubital fossa, groin, and periumbilical areas.[2,3]

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