Differential effects of typical and atypical neuroleptics on mitochondrial functionin vitro

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Archives of pharmacal research

• Publication date

  2003-11-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1007/BF02980205PMID 14661862
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2004cited by this paper
• Choosing an atypical antipsychotic.

  2002cited by this paper
• Effects of Newer Antipsychotics on Extrapyramidal Function

  2002cited by this paper
• Risk of Extrapyramidal Syndromes with Haloperidol, Risperidone, or Olanzapine

  2001cited by this paper
• Extrapyramidal side effects, tardive dyskinesia, and the concept of atypicality.

  2000cited by this paper
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  2000cited by this paper
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  1999cited by this paper
• Inhibition of mitochondrial complex I by haloperidol: the role of thiol oxidation.

  1999cited by this paper
• Lower Incidence of Tardive Dyskinesia with Risperidone Compared with Haloperidol in Older Patients

  1999cited by this paper
• Mitochondria and apoptosis.

  1998cited by this paper
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  1997cited by this paper
• Neuroleptic-induced mitochondrial enzyme alterations in the rat brain.

  1997cited by this paper
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  1997cited by this paper
• Extrapyramidal Syndromes and New Antipsychotic Drugs: Findings in Patients and Non-human Primate Models

  1996cited by this paper
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  1995cited by this paper
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  1995cited by this paper
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  1995cited by this paper
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  1995cited by this paper
• Thermal habit, metabolic rate and the evolution of mitochondrial DNA.

  1994cited by this paper
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  1994cited by this paper
• Neuroleptic medications inhibit complex I of the electron transport chain

  1993cited by this paper
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  1993cited by this paper
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  1992cited by this paper
• Mitochondrial toxicity of cationic photosensitizers for photochemotherapy.

  1990cited by this paper
• Tardive dyskinesia.

  1984cited by this paper
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  1979cited by this paper
• The effect of phenothiazine on the metabolism of liver mitochondria.

  1965cited by this paper
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  1964cited by this paper
• Effects of chlorpromazine on metabolism in central nervous system.

  1955cited by this paper

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  2025cites this paper
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  2023cites this paper
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  2023cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2017cites this paper
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  2017cites this paper
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  2008influential citation
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  2007cites this paper
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