Immunological network analysis in HPV associated head and neck squamous cancer and implications for disease prognosis

No abstract is available for this paper.

• Publication year

  2018

• Venue

  Molecular Immunology

• Publication date

  2018-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.molimm.2018.02.005PMID 29477933
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Erratum to: Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA signatures

  2017cited by this paper
• Chlorogenic acid inhibits glioblastoma growth through repolarizating macrophage from M2 to M1 phenotype

  2017cited by this paper
• Gene expression analysis of TIL rich HPV-driven head and neck tumors reveals a distinct B-cell signature when compared to HPV independent tumors

  2016cited by this paper
• Repeated observation of immune gene sets enrichment in women with non-small cell lung cancer

  2016cited by this paper
• Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA signatures

  2016cited by this paper
• High-throughput genomic profiling of tumor-infiltrating leukocytes.

  2016cited by this paper
• Stromal infiltration of CD8 T cells is associated with improved clinical outcome in HPV-positive oropharyngeal squamous carcinoma

  2015cited by this paper
• Opposite Effects of M1 and M2 Macrophage Subtypes on Lung Cancer Progression

  2015cited by this paper
• The Evolution of T-cell Therapies for Solid Malignancies

  2015cited by this paper
• Head and Neck Cancer Stem Cells

  2015cited by this paper
• Tumour, Oxidative Stress and Host T Cell Response: Cementing the Dominance

  2015cited by this paper
• Robust enumeration of cell subsets from tissue expression profiles

  2015cited by this paper
• HPV in oropharyngeal cancer: the basics to know in clinical practice

  2014cited by this paper
• Occurrence of Tertiary Lymphoid Tissue Is Associated with T-Cell Infiltration and Predicts Better Prognosis in Early-Stage Colorectal Cancers

  2014cited by this paper
• The tumour-induced systemic environment as a critical regulator of cancer progression and metastasis

  2014cited by this paper
• HPV associated tumor cells control tumor microenvironment and leukocytosis in experimental models

  2014cited by this paper
• Prognostic B-cell Signatures Using mRNA-Seq in Patients with Subtype-Specific Breast and Ovarian Cancer

  2014cited by this paper
• Prevalence of Human Papillomavirus in Oropharyngeal Squamous Cell Carcinoma in the United States Across Time

  2014cited by this paper
• Promoting effect of neutrophils on lung tumorigenesis is mediated by CXCR2 and neutrophil elastase

  2013cited by this paper
• Inferring tumour purity and stromal and immune cell admixture from expression data

  2013cited by this paper
• Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer.

  2013cited by this paper
• The immune contexture in human tumours: impact on clinical outcome

  2012cited by this paper
• Discrimination of ‘Driver’ and ‘Passenger’ HPV in Tonsillar Carcinomas by the Polymerase Chain Reaction, Chromogenic In Situ Hybridization, and p16INK4a Immunohistochemistry

  2011cited by this paper
• Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

  2009cited by this paper
• An Entropy-based gene selection method for cancer classification using microarray data

  2005cited by this paper
• Human papillomavirus types 6 and 11 DNA sequences in genital and laryngeal papillomas and in some cervical cancers.

  1983cited by this paper

• Targeting archetypes of viral-driven cancers with immunotherapy: a perspective on immunogenicity within the tumor microenvironment

  2025cites this paper
• Based on disulfide accumulation, leveraging a THBS1-signature to improve the outcome of head and neck carcinoma patients.

  2025cites this paper
• Virale und nichtvirale Karzinogenese bei Oropharynxkarzinomen – humane Papillomaviren als Karzinogen

  2025cites this paper
• M1 macrophage-derived exosomal miR-20b promotes radiosensitization via CCND1 in HPV+ HNSCC

  2025cites this paper
• Richness for Tumor-Infiltrating B-Cells in the Oral Cancer Tumor Microenvironment Is a Prognostic Factor in Early-Stage Disease and Improves Outcome in Advanced-Stage Disease

  2025cites this paper
• Liquid Biopsy in HPV-Associated Head and Neck Cancer: A Comprehensive Review

  2025cites this paper
• The role of tumor-associated neutrophils in the pathogenesis of recurrent respiratory papillomatosis.

  2025cites this paper
• Prognostic influence of chronic inflammation in patients with head and neck cancer based on sex differences

  2025cites this paper
• Regorafenib enhances M1/M2 macrophage polarization by inhibiting the secretion of plasminogen activator inhibitor-1 in head and neck squamous cell carcinoma.

  2024cites this paper
• Heterogeneous characterization of neutrophilic cells in head and neck cancers

  2024cites this paper
• B cells in head and neck squamous cell carcinoma: current opinion and novel therapy

  2024cites this paper
• Comparative analysis of immune infiltrates in head and neck cancers across anatomical sites

  2024cites this paper
• Comparative study of pathogen detection methods for central nervous system infections: laboratory testing of tuberculous meningitis

  2024cites this paper
• Human papillomavirus E6/E7 oncoproteins promote radiotherapy-mediated tumor suppression by globally hijacking host DNA damage repair

  2023cites this paper
• CD161 Characterizes an Inflamed Subset of Cytotoxic T Lymphocytes Associated with Prolonged Survival in Human Papillomavirus–Driven Oropharyngeal Cancer

  2023cites this paper
• The tumor ecosystem in head and neck squamous cell carcinoma and advances in ecotherapy

  2023cites this paper
• LncRNA SELL/L-selectin Promotes HPV-Positive HNSCC Progression and Drives Fucoidan-Mediated Therapeutic Strategies.

  2023cites this paper
• The Role of Different Immunocompetent Cell Populations in the Pathogenesis of Head and Neck Cancer—Regulatory Mechanisms of Pro- and Anti-Cancer Activity and Their Impact on Immunotherapy

  2023cites this paper
• Tumor cell-derived exosomes regulate macrophage polarization: Emerging directions in the study of tumor genesis and development

  2023cites this paper
• Immune-scoring in head and neck squamous cell carcinoma: a scoping review

  2023cites this paper
• HPV-Negative and HPV-Positive Oral Cancer Cells Stimulate the Polarization of Neutrophils towards Different Functional Phenotypes In Vitro

  2023cites this paper
• The Two Faces of Immune-Related lncRNAs in Head and Neck Squamous Cell Carcinoma

  2023cites this paper
• Exosomes Participate in the Radiotherapy Resistance of Cancers

  2022influential citation
• Clinicopathological and Prognostic Significance of Stromal Patterns in Oral Squamous Cell Carcinoma

  2022cites this paper
• Immune Landscape and Role of Immunotherapy in Treatment of HPV-Associated Head and Neck Squamous Cell Carcinoma (HNSCC)

  2022cites this paper
• The Role of Immune Modulatory Cytokines in the Tumor Microenvironments of Head and Neck Squamous Cell Carcinomas

  2022cites this paper
• Implications and Emerging Therapeutic Avenues of Inflammatory Response in HPV+ Head and Neck Squamous Cell Carcinoma

  2022cites this paper
• Bowen disease of the nail unit associated with HPV-16 infection in a pemphigus patient following rituximab treatment

  2022cites this paper
• Metformin increases natural killer cell functions in head and neck squamous cell carcinoma through CXCL1 inhibition

  2022cites this paper
• Radioimmunotherapy in HPV-Associated Head and Neck Squamous Cell Carcinoma

  2022cites this paper
• Single-cell RNA sequencing reveals TCR+ macrophages in HPV-related head and neck squamous cell carcinoma

  2022cites this paper
• Pretreatment nutritional status, HPV infection, and tumor infiltrating lymphocyte as prognostic predictors in patients with head and neck squamous cell carcinoma after chemotherapy

  2022cites this paper
• Improving head and neck cancer therapies by immunomodulation of the tumour microenvironment

  2022cites this paper
• Bioinformatic analysis identifies HPV-related tumor microenvironment remodeling prognostic biomarkers in head and neck squamous cell carcinoma

  2022cites this paper
• Dealing with Macrophage Plasticity to Address Therapeutic Challenges in Head and Neck Cancers

  2022cites this paper
• Transcriptome analysis reveals the prognostic and immune in ltration characteristics of glycolysis and hypoxia in head and neck squamous cell carcinoma

  2021cites this paper
• Tumor microenvironment: an evil nexus promoting aggressive head and neck squamous cell carcinoma and avenue for targeted therapy

  2021cites this paper
• Identification of Immune-Related Prognostic Biomarkers Associated with HPV-Positive Head and Neck Squamous Cell Carcinoma

  2021cites this paper
• Characteristics of B lymphocyte infiltration in HPV+ head and neck squamous cell carcinoma

  2021cites this paper
• Increased Abundance of Tumour-Associated Neutrophils in HPV-Negative Compared to HPV-Positive Oropharyngeal Squamous Cell Carcinoma Is Mediated by IL-1R Signalling

  2021influential citation
• DOCK8 Serves as a Prognostic Biomarker and Is Related to Immune Infiltration in Patients With HPV Positive Head and Neck Squamous Cell Carcinoma

  2021cites this paper
• High SEC61G expression predicts poor prognosis in patients with Head and Neck Squamous Cell Carcinomas

  2021cites this paper
• Distinct Patterns of Myeloid Cell Infiltration in Patients With hrHPV-Positive and hrHPV-Negative Penile Squamous Cell Carcinoma: The Importance of Assessing Myeloid Cell Densities Within the Spatial Context of the Tumor

  2021cites this paper
• Precision Medicine Gains Momentum: Novel 3D Models and Stem Cell-Based Approaches in Head and Neck Cancer

  2021cites this paper
• Rapid Serial Immunoprofiling of the Tumor Immune Microenvironment by Fine Needle Sampling

  2021cites this paper
• Phytochemicals as Potential Chemopreventive and Chemotherapeutic Agents for Emerging Human Papillomavirus–Driven Head and Neck Cancer: Current Evidence and Future Prospects

  2021cites this paper
• Correlation between HPV infection and ovarian epithelial cancer diagnosed by Dynamic Contrast-enhanced magnetic resonance imaging information technology under exponential distribution mathematical model

  2021cites this paper
• Immunotherapy in Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck

  2021cites this paper
• Impact of human papillomavirus on the tumor microenvironment in oropharyngeal squamous cell carcinoma

  2021cites this paper
• The Key Differences between Human Papillomavirus-Positive and -Negative Head and Neck Cancers: Biological and Clinical Implications

  2021cites this paper
• The tumor immune microenvironments of HPV+ and HPV- head and neck cancers.

  2021cites this paper
• Transcriptome analysis reveals the prognostic and immune infiltration characteristics of glycolysis and hypoxia in head and neck squamous cell carcinoma

  2021cites this paper
• Importance of immune cell infiltration in tumor microenvironment of head and neck cancer

  2021cites this paper
• Transcriptomics and Epigenomics in head and neck cancer: available repositories and molecular signatures

  2020cites this paper
• The exploration of new therapeutic targets for HPV‐negative head and neck squamous cell cancer through the construction of a ceRNA network and immune microenvironment analysis

  2020cites this paper
• Human Papillomavirus Infection in Head and Neck Squamous Cell Carcinomas: Transcriptional Triggers and Changed Disease Patterns

  2020cites this paper
• Myeloid cell-targeted STAT3 inhibition sensitizes head and neck cancers to radiotherapy and T cell-mediated immunity.

  2020cites this paper
• PRINS lncRNA Is a New Biomarker Candidate for HPV Infection and Prognosis of Head and Neck Squamous Cell Carcinomas

  2020cites this paper
• Immune Escape Mechanisms and Their Clinical Relevance in Head and Neck Squamous Cell Carcinoma

  2020cites this paper
• Immunological Network in Head and Neck Squamous Cell Carcinoma—A Prognostic Tool Beyond HPV Status

  2020cites this paper
• Comprehensive analysis of significant genes and immune cell infiltration in HPV-related head and neck squamous cell carcinoma.

  2020cites this paper
• The Immune Microenvironment in Head and Neck Squamous Cell Carcinoma: on Subsets and Subsites

  2020cites this paper
• M2 macrophages reduce the radiosensitivity of head and neck cancer by releasing HB-EGF

  2020cites this paper
• Interplay between cancer cells and M2 macrophages is necessary for miR-550a-3-5p down-regulation-mediated HPV-positive OSCC progression

  2020cites this paper
• regulation-mediated HPV-positive OSCC progression

  2020cites this paper
• HPV+ HNSCC-Derived Exosomal miR-9 Induces Macrophage M1 Polarization and Increases Tumor Radiosensitivity.

  2020cites this paper
• The Double-Edged Sword—How Human Papillomaviruses Interact With Immunity in Head and Neck Cancer

  2019cites this paper
• The Epigenetic And Immune Landscapes Of HPV+ Tumor Microenvironments

  2019cites this paper
• HPV-positive head and neck cancer derived exosomal miR-9 induces M1 macrophage polarization and increases tumor radiosensitivity

  2019cites this paper
• Relationship between inflammation and the severity of Recurrent Respiratory Papillomatosis.

  2019cites this paper
• Enhanced Radiation Sensitivity of Human Papillomavirus-Driven Head and Neck Cancer: Focus on Immunological Aspects

  2019cites this paper
• CMAR_A_202465 5171..5185

  2019cites this paper
• High Level Expression of MHC-II in HPV+ Head and Neck Cancers Suggests that Tumor Epithelial Cells Serve an Important Role as Accessory Antigen Presenting Cells

  2019cites this paper
• The Host-Microbe Interplay in Human Papillomavirus-Induced Carcinogenesis

  2019cites this paper
• Neutrophils infiltration and its correlation with human papillomavirus status in the oral squamous cell carcinoma

  2019cites this paper
• Identifying predictors of HPV-related head and neck squamous cell carcinoma progression and survival through patient-derived models

  2019cites this paper
• IL-6 induced M1 type macrophage polarization increases radiosensitivity in HPV positive head and neck cancer.

  2019cites this paper
• Modulation of radiation sensitivity and antitumor immunity by viral pathogenic factors: Implications for radio-immunotherapy.

  2019cites this paper
• Utility of CD8 score by automated quantitative image analysis in head and neck squamous cell carcinoma.

  2018cites this paper
• Treatment-naïve HPV+ head and neck cancers display a T-cell-inflamed phenotype distinct from their HPV- counterparts that has implications for immunotherapy

  2018influential citation