NMDA receptors amplify mossy fiber synaptic inputs at frequencies up to at least 750 Hz in cerebellar granule cells

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Synapse

• Publication date

  2016-07-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1002/syn.21898PMID 26887562
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Excitatory Cerebellar Nucleocortical Circuit Provides Internal Amplification during Associative Conditioning

  2016influential reference
• Multimodal sensory integration in single cerebellar granule cells in vivo

  2015cited by this paper
• Dendritic patch-clamp recordings from cerebellar granule cells demonstrate electrotonic compactness

  2015cited by this paper
• Frequency‐dependent facilitation of synaptic throughput via postsynaptic NMDA receptors in the nucleus of the solitary tract

  2015cited by this paper
• Synaptic diversity enables temporal coding of coincident multi-sensory inputs in single neurons

  2015cited by this paper
• Regulation of output spike patterns by phasic inhibition in cerebellar granule cells

  2014cited by this paper
• Ultrafast action potentials mediate kilohertz signaling at a central synapse.

  2014cited by this paper
• Convergence of pontine and proprioceptive streams onto multimodal cerebellar granule cells

  2013cited by this paper
• NMDA Receptors with Incomplete Mg2+ Block Enable Low-Frequency Transmission through the Cerebellar Cortex

  2012cited by this paper
• Ultrafast Population Encoding by Cortical Neurons

  2011cited by this paper
• NMDA Currents Modulate the Synaptic Input–Output Functions of Neurons in the Dorsal Nucleus of the Lateral Lemniscus in Mongolian Gerbils

  2011cited by this paper
• Neuronal arithmetic

  2010cited by this paper
• Sensitivity to perturbations in vivo implies high noise and suggests rate coding in cortex

  2010cited by this paper
• Bassoon Speeds Vesicle Reloading at a Central Excitatory Synapse

  2010cited by this paper
• The cerebellar microcircuit as an adaptive filter: experimental and computational evidence

  2010cited by this paper
• The advantages of linear information processing for cerebellar computation

  2009influential reference
• Reliability and Precision of the Mouse Calyx of Held Synapse

  2009cited by this paper
• NMDA receptor activation by spontaneous glutamatergic neurotransmission.

  2009cited by this paper
• Synaptic depression enables neuronal gain control

  2009cited by this paper
• Mechanisms of Potentiation of Mossy Fiber EPSCs in the Cerebellar Nuclei by Coincident Synaptic Excitation and Inhibition

  2008cited by this paper
• The Contribution of Single Synapses to Sensory Representation in Vivo

  2008influential reference
• Spontaneous and Evoked Glutamate Release Activates Two Populations of NMDA Receptors with Limited Overlap

  2008cited by this paper
• Frequency-independent synaptic transmission supports a linear vestibular behavior.

  2008cited by this paper
• High-fidelity transmission of sensory information by single cerebellar mossy fibre boutons

  2007cited by this paper
• Synaptic activation of dendritic AMPA and NMDA receptors generates transient high-frequency firing in substantia nigra dopamine neurons in vitro.

  2007cited by this paper
• An analysis of glutamate spillover on the N-methyl-D-aspartate receptors at the cerebellar glomerulus

  2007cited by this paper
• Fast vesicle reloading and a large pool sustain high bandwidth transmission at a central synapse

  2006cited by this paper
• Properties of Somatosensory Synaptic Integration in Cerebellar Granule Cells In Vivo

  2006cited by this paper
• Potentiation of mossy fiber EPSCs in the cerebellar nuclei by NMDA receptor activation followed by postinhibitory rebound current.

  2006cited by this paper
• Rapid Vesicular Release, Quantal Variability, and Spillover Contribute to the Precision and Reliability of Transmission at a Glomerular Synapse

  2005cited by this paper
• The Effect of NMDA Receptors on Gain Modulation

  2005cited by this paper
• Integration of quanta in cerebellar granule cells during sensory processing

  2004cited by this paper
• Maturation of EPSCs and Intrinsic Membrane Properties Enhances Precision at a Cerebellar Synapse

  2003influential reference
• The Contribution of NMDA and AMPA Conductances to the Control of Spiking in Neurons of the Deep Cerebellar Nuclei

  2003cited by this paper
• Active release of glycine or d‐serine saturates the glycine site of NMDA receptors at the cerebellar mossy fibre to granule cell synapse

  2003cited by this paper
• Spillover of glutamate onto synaptic AMPA receptors enhances fast transmission at a cerebellar synapse.

  2002cited by this paper
• NMDA Receptor 2 (NR2) C-Terminal Control of NR Open Probability Regulates Synaptic Transmission and Plasticity at a Cerebellar Synapse

  2002cited by this paper
• NMDA receptor-mediated currents in rat cerebellar granule and unipolar brush cells.

  2002cited by this paper
• Fine-Tuning an Auditory Synapse for Speed and Fidelity: Developmental Changes in Presynaptic Waveform, EPSC Kinetics, and Synaptic Plasticity

  2000cited by this paper
• Long-Term Potentiation of Intrinsic Excitability at the Mossy Fiber–Granule Cell Synapse of Rat Cerebellum

  2000cited by this paper
• Developmental Profile of the Changing Properties of NMDA Receptors at Cerebellar Mossy Fiber–Granule Cell Synapses

  2000cited by this paper
• Evidence for NMDA and mGlu receptor-dependent long-term potentiation of mossy fiber-granule cell transmission in rat cerebellum.

  1999cited by this paper
• Cutaneous receptive fields and topography of mossy fibres and climbing fibres projecting to cat cerebellar C3 zone

  1998cited by this paper
• Physiological properties of inhibitory interneurons in cat striate cortex.

  1997cited by this paper
• Relationship Between GAP‐43 Expression in the Dentate Gyrus and Synaptic Reorganization of Hippocampal Mossy Fibres in Rats Treated with Kainic Acid

  1997cited by this paper
• Spikes: Exploring the Neural Code

  1996cited by this paper
• Functional Correlation of NMDA Receptor ε Subunits Expression with the Properties of Single-Channel and Synaptic Currents in the Developing Cerebellum

  1996cited by this paper
• Deactivation and desensitization of non‐NMDA receptors in patches and the time course of EPSCs in rat cerebellar granule cells.

  1996cited by this paper
• Synaptic excitation of individual rat cerebellar granule cells in situ: evidence for the role of NMDA receptors.

  1995cited by this paper
• Frequency dependent activation of a slow N-methyl-D-aspartate-dependent excitatory postsynaptic potential in turtle cerebellum by mossy fibre afferents.

  1995cited by this paper
• Synaptic integration in a model of cerebellar granule cells.

  1994cited by this paper
• Developmental and regional expression in the rat brain and functional properties of four NMDA receptors.

  1994cited by this paper
• NMDA-receptor channel diversity in the developing cerebellum

  1994cited by this paper
• Movement-related inputs to intermediate cerebellum of the monkey.

  1993influential reference
• Rapid-time-course miniature and evoked excitatory currents at cerebellar synapses in situ

  1992cited by this paper
• Frequency-dependent involvement of NMDA receptors in the hippocampus: a novel synaptic mechanism

  1986cited by this paper
• Frontiers in Cellular Neuroscience Cellular Neuroscience

  year unknowncited by this paper

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  2022cites this paper
• Computational models of neurotransmission at cerebellar synapses unveil the impact on network computation

  2022cites this paper
• Gradients in the mammalian cerebellar cortex enable Fourier-like transformation and improve storing capacity

  2020cites this paper
• Gradients in the cerebellar cortex enable Fourier-like transformation and improve storing capacity

  2019influential citation
• Electrogenic N‐methyl‐D‐aspartate receptor signaling enhances binaural responses in the adult brainstem

  2018cites this paper
• The Cerebellar Mossy Fiber Synapse as a Model for High-Frequency Transmission in the Mammalian CNS.

  2016cites this paper