Influence of protein/glycan interaction on site‐specific glycan heterogeneity

No abstract is available for this paper.

• Publication year

  2017

• Venue

  The FASEB Journal

• Publication date

  2017-07-05

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1096/fj.201700403RPMID 28679530
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Stabilizing the CH2 Domain of an Antibody by Engineering in an Enhanced Aromatic Sequon.

  2016cited by this paper
• Metabolic Reprogramming by Hexosamine Biosynthetic and Golgi N-Glycan Branching Pathways

  2016cited by this paper
• N-linked glycosylation and homeostasis of the endoplasmic reticulum.

  2016cited by this paper
• A theoretical estimate for nucleotide sugar demand towards Chinese Hamster Ovary cellular glycosylation

  2016cited by this paper
• N-glycoprotein macroheterogeneity: biological implications and proteomic characterization

  2016cited by this paper
• Dynamics of immature mAb glycoform secretion during CHO cell culture: An integrated modelling framework.

  2016cited by this paper
• Predominant Expression of Hybrid N-Glycans Has Distinct Cellular Roles Relative to Complex and Oligomannose N-Glycans

  2016cited by this paper
• Integrated Omics and Computational Glycobiology Reveal Structural Basis for Influenza A Virus Glycan Microheterogeneity and Host Interactions

  2016cited by this paper
• Controlling the time evolution of mAb N‐linked glycosylation ‐ Part II: Model‐based predictions

  2016cited by this paper
• The Dependence of Carbohydrate-Aromatic Interaction Strengths on the Structure of the Carbohydrate.

  2016cited by this paper
• Enhanced Aromatic Sequons Increase Oligosaccharyltransferase Glycosylation Efficiency and Glycan Homogeneity.

  2015cited by this paper
• Glycoengineering of Chinese hamster ovary cells for enhanced erythropoietin N‐glycan branching and sialylation

  2015cited by this paper
• Chinese hamster ovary (CHO) host cell engineering to increase sialylation of recombinant therapeutic proteins by modulating sialyltransferase expression

  2015cited by this paper
• Strategies for Engineering Protein N-Glycosylation Pathways in Mammalian Cells.

  2015cited by this paper
• Analysis of site-specific N-glycan remodeling in the endoplasmic reticulum and the Golgi.

  2015cited by this paper
• Two Classes of Broadly Neutralizing Antibodies within a Single Lineage Directed to the High-Mannose Patch of HIV Envelope

  2014cited by this paper
• Glycobiology of leukocyte traf fi cking in in fl ammation

  2014cited by this paper
• Glycobiology of leukocyte trafficking in inflammation.

  2014cited by this paper
• The choice of mammalian cell host and possibilities for glycosylation engineering.

  2014cited by this paper
• Diversity in structure and functions of antibody sialylation in the Fc.

  2014cited by this paper
• CHO glycosylation mutants as potential host cells to produce therapeutic proteins with enhanced efficacy.

  2013cited by this paper
• Engineering Hydrophobic Protein–Carbohydrate Interactions to Fine-Tune Monoclonal Antibodies

  2013cited by this paper
• Vertebrate protein glycosylation: diversity, synthesis and function

  2012cited by this paper
• Emerging technologies for making glycan-defined glycoproteins.

  2012cited by this paper
• Site-specific protein glycosylation analysis with glycan isomer differentiation

  2012cited by this paper
• Mapping N-glycosylation sites across seven evolutionarily distant species reveals a divergent substrate proteome despite a common core machinery.

  2012cited by this paper
• N‐glycosylation of enhanced aromatic sequons to increase glycoprotein stability

  2012cited by this paper
• Glycosylation of the enhanced aromatic sequon is similarly stabilizing in three distinct reverse turn contexts

  2011cited by this paper
• Golgi glycosylation.

  2011cited by this paper
• Similarities and Differences in the Glycosylation Mechanisms in Prokaryotes and Eukaryotes

  2011cited by this paper
• A dynamic mathematical model for monoclonal antibody N‐linked glycosylation and nucleotide sugar donor transport within a maturing Golgi apparatus

  2011cited by this paper
• N-linked protein glycosylation in the endoplasmic reticulum

  2010influential reference
• N-glycan structures: recognition and processing in the ER.

  2010influential reference
• Glycomics Profiling of Chinese Hamster Ovary Cell Glycosylation Mutants Reveals N-Glycans of a Novel Size and Complexity*

  2009cited by this paper
• A mutual regulation between cell-cell adhesion and N-glycosylation: implication of the bisecting GlcNAc for biological functions.

  2009cited by this paper
• Expression systems for therapeutic glycoprotein production.

  2009cited by this paper
• Optimal and consistent protein glycosylation in mammalian cell culture.

  2009cited by this paper
• Universal sample preparation method for proteome analysis

  2009cited by this paper
• Universal sample preparation method for proteome analysis

  2009cited by this paper
• Protein-glycan interactions in the control of innate and adaptive immune responses

  2008cited by this paper
• Development of a simple and rapid method for producing non‐fucosylated oligomannose containing antibodies with increased effector function

  2008cited by this paper
• Golgi α-mannosidase II cleaves two sugars sequentially in the same catalytic site

  2008cited by this paper
• Higher levels of sialylated Fc glycans in immunoglobulin G molecules can adversely impact functionality.

  2007cited by this paper
• Glycosylation of therapeutic proteins in different production systems

  2007cited by this paper
• The crystal structure of yeast protein disulfide isomerase suggests cooperativity between its active sites.

  2006cited by this paper
• Lectin-resistant CHO glycosylation mutants.

  2006cited by this paper
• Site-specific glycosylation analysis of the bovine lysosomal α-mannosidase

  2006cited by this paper
• Family 47 alpha-mannosidases in N-glycan processing.

  2006cited by this paper
• Family 47 α‐Mannosidases in N‐Glycan Processing

  2006cited by this paper
• Site-specific glycosylation analysis of the bovine lysosomal alpha-mannosidase.

  2006cited by this paper
• Establishment of FUT8 knockout Chinese hamster ovary cells: An ideal host cell line for producing completely defucosylated antibodies with enhanced antibody‐dependent cellular cytotoxicity

  2004cited by this paper
• Defucosylated Chimeric Anti-CC Chemokine Receptor 4 IgG1 with Enhanced Antibody-Dependent Cellular Cytotoxicity Shows Potent Therapeutic Activity to T-Cell Leukemia and Lymphoma

  2004cited by this paper
• N-linked protein glycosylation in the endoplasmic reticulum.

  2000cited by this paper
• Genetic engineering of recombinant glycoproteins and glycosylation pathway in mammalian host cells

  1999cited by this paper
• Factors controlling the glycosylation potential of the Golgi apparatus.

  1998cited by this paper
• The 'yellow brick road' to branched complex N-glycans.

  1991cited by this paper
• Regulation of glycosylation. The influence of protein structure on N-linked oligosaccharide processing.

  1988cited by this paper
• Biosynthetic controls that determine the branching and microheterogeneity of protein-bound oligosaccharides.

  1986cited by this paper
• Biosynthetic controls that determine the branching and microheterogeneity of protein-bound oligosaccharides.

  1986cited by this paper
• Structures of N-glycans of a ricin-resistant mutant of baby hamster kidney cells. Synthesis of high-mannose and hybrid N-glycans.

  1985cited by this paper
• GlycoProtein biosynthesis in yeast. protein conformation affects processing of high mannose oligosaccharides on carboxypeptidase Y and invertase.

  1983cited by this paper
• Host-dependent variation of asparagine-linked oligosaccharides at individual glycosylation sites of Sindbis virus glycoproteins.

  1983cited by this paper

• Microfluidic mimicry of the Golgi-linked N-glycosylation machinery.

  2025cites this paper
• Precision Glycoform Engineering: Combining plant and in vitro systems for tailored biopharmaceutical production

  2025cites this paper
• A hierarchical structure in the N-glycosylation process governs the N-glycosylation output: prolonged cultivation induces glycoenzymes expression variations that are reflected in the cellular N-glycome but not in the protein and site-specific glycoprofile of CHO cells

  2024cites this paper
• Decoding glycosylation potential from protein structure across human glycoproteins with a multi-view recurrent neural network

  2024cites this paper
• SLC3A2 N-glycosylation and Golgi remodeling regulate SLC7A amino acid exchangers and stress mitigation

  2023cites this paper
• Restoring protein glycosylation with GlycoShape

  2023cites this paper
• Decoding human-macaque interspecies differences in Fc-effector functions: The structural basis for CD16-dependent effector function in Rhesus macaques

  2022cites this paper
• Sequential in vitro enzymatic N-glycoprotein modification reveals site-specific rates of glycoenzyme processing

  2022influential citation
• Glycoinformatics in the Artificial Intelligence Era

  2022cites this paper
• Glycosylation network mapping and site-specific glycan maturation in vivo

  2022influential citation
• A graphical representation of glycan heterogeneity.

  2021cites this paper
• Mechanistic and data-driven modeling of protein glycosylation

  2021cites this paper
• Analysis of secretome and N-glycosylation of Chlorella species

  2021cites this paper
• N-Glycosylation Enhances Conformational Flexibility of Protein Disulfide Isomerase Revealed by Microsecond Molecular Dynamics and Markov State Modeling.

  2021cites this paper
• Potential Molecular Players Against to SARS-CoV-2: A Glyco-Perspective

  2021cites this paper
• Glycoengineering Chinese hamster ovary cells: a short history

  2021cites this paper
• Towards rational glyco-engineering in CHO: from data to predictive models.

  2021cites this paper
• Production of microhomogeneous glycopeptide by a mutated NGT according FuncLib with unique sugar as substrate.

  2021cites this paper
• Comprehensive analysis of lactoferrin N-glycans with site-specificity from bovine colostrum using specific proteases and RP-UHPLC-MS/MS

  2021cites this paper
• Glycan–protein interactions determine kinetics of N-glycan remodeling

  2021cites this paper
• Perfusion Bioreactors:The Set-Up and Process Characterisation

  2020cites this paper
• Sequential Glycosylation of Proteins with Substrate-Specific N-Glycosyltransferases

  2020cites this paper
• SweetOrigins: Extracting Evolutionary Information from Glycans

  2020cites this paper
• How glycosylation affects glycosylation: the role of N-glycans in glycosyltransferase activity.

  2020cites this paper
• Synthetic Glycobiology: Parts, Systems, and Applications

  2020cites this paper
• Perfusion Cell Culture Processes for Biopharmaceuticals

  2020cites this paper
• Glycan-Protein Interactions Determine Kinetics of N-Glycan Remodeling

  2020cites this paper
• 3D Models of glycosylated SARS-CoV-2 spike protein suggest challenges and opportunities for vaccine development

  2020cites this paper
• Big-Data Glycomics: Tools to Connect Glycan Biosynthesis to Extracellular Communication.

  2020cites this paper
• Perfusion Mammalian Cell Culture for Recombinant Protein Manufacturing

  2020cites this paper
• Design and Optimisation of Mammalian Cell Perfusion Cultures

  2020cites this paper
• Scale-Down Models and Sensors for Process Development

  2020cites this paper
• Generation of site‐distinct N‐glycan variants for in vitro bioactivity testing

  2019cites this paper
• Bacterial antibody hydrolyzing enzymes – as bacterial virulence factors and biotechnological tools

  2019cites this paper
• Translation of genome to glycome: role of the Golgi apparatus

  2019cites this paper
• Revisiting the Language of Glycoscience: Readers, Writers and Erasers in Carbohydrate Biochemistry

  2019cites this paper
• Modeling Glycan Processing Reveals Golgi-Enzyme Homeostasis upon Trafficking Defects and Cellular Differentiation

  2019cites this paper
• Galectins as Adaptors: Linking Glycosylation and Metabolism with Extracellular Cues

  2018cites this paper
• The contributions of individual galactosyltransferases to protein specific N-glycan processing in Chinese Hamster Ovary cells.

  2018cites this paper
• Lab on a Chip COMMUNICATION

  year unknowninfluential citation