Autophagy-assisted antigen cross-presentation

It is generally believed that most tumor antigens are passively released from either health or dying tumor cells as intact soluble antigens, peptide fragments complexed with heat shock proteins (HSPs), or packaged in secretary vesicles in the form of microparticles or exosomes. The passive release of tumor antigens is generally non-inflammatory and non-immunogenic; however, results from others and our laboratories suggest that autophagy is critically involved in immunogenic cell death.

• Publication year

  2012

• Venue

  Oncoimmunology

• Publication date

  2012-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4161/onci.20059PMID 23162777PMCID 3489765
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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