Effect of a centrally active angiotensin converting enzyme inhibitor, perindopril, on cognitive performance in chronic cerebral hypo-perfusion rats.

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Brain Research

• Publication date

  2011-11-03

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/j.brainres.2011.09.016PMID 21981801
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Perindopril, a centrally active angiotensin‐converting enzyme inhibitor, prevents cognitive impairment in mouse models of Alzheimer's disease

  2011cited by this paper
• Angiotensin II-inhibiting drugs have no effect on intraneuronal Aβ or oligomeric Aβ levels in a triple transgenic mouse model of Alzheimer's disease.

  2011cited by this paper
• Associations of Anti-Hypertensive Treatments with Alzheimer's Disease, Vascular Dementia, and Other Dementias

  2011cited by this paper
• Osthole improves chronic cerebral hypoperfusion induced cognitive deficits and neuronal damage in hippocampus.

  2010cited by this paper
• Effect of a centrally active angiotensin-converting enzyme inhibitor, perindopril, on cognitive performance in a mouse model of Alzheimer's disease.

  2010cited by this paper
• Use of angiotensin receptor blockers and risk of dementia in a predominantly male population: prospective cohort analysis

  2010cited by this paper
• Angiotensin-converting enzyme inhibitors and cognitive decline in older adults with hypertension: results from the Cardiovascular Health Study.

  2009influential reference
• Angiotensin-converting enzyme levels and activity in Alzheimer's disease: differences in brain and CSF ACE and association with ACE1 genotypes.

  2009cited by this paper
• Vascular risk factors and dementia

  2009cited by this paper
• VASCULAR RISK FACTORS AND DEMENTIA: HOW TO MOVE FORWARD?

  2009cited by this paper
• Huperzine a improves chronic inflammation and cognitive decline in rats with cerebral hypoperfusion

  2009cited by this paper
• Abeta42-to-Abeta40- and angiotensin-converting activities in different domains of angiotensin-converting enzyme.

  2009cited by this paper
• The Use of Angiotensin‐converting Enzyme Inhibitors and Diuretics Is Associated With a Reduced Incidence of Impairment on Cognition in Elderly Women

  2008cited by this paper
• Altered angiotensin-converting enzyme and its effects on the brain in a rat model of Alzheimer disease.

  2008cited by this paper
• NVOLVEMENT OF ANGIOTENSIN CONVERTING ENZYME IN EREBRAL HYPOPERFUSION INDUCED ANTEROGRADE MEMORY MPAIRMENT AND CHOLINERGIC DYSFUNCTION IN RATS

  2008cited by this paper
• Permanent, bilateral common carotid artery occlusion in the rat: a model for chronic cerebral hypoperfusion-related neurodegenerative diseases.

  2007cited by this paper
• Effects of prolonged angiotensin-converting enzyme inhibitor treatment on amyloid beta-protein metabolism in mouse models of Alzheimer disease.

  2007cited by this paper
• Effect of chronic angiotensin converting enzyme inhibition on spatial memory and anxiety-like behaviours in rats.

  2007cited by this paper
• Angiotensin II disrupts inhibitory avoidance memory retrieval.

  2006cited by this paper
• Angiotensin converting enzyme (ACE) inhibitors modulate the rate of progression of amnestic mild cognitive impairment

  2006cited by this paper
• The effects of commonly prescribed drugs in patients with Alzheimer’s disease on the rate of deterioration

  2006cited by this paper
• Regulation of Steady-state β-Amyloid Levels in the Brain by Neprilysin and Endothelin-converting Enzyme but Not Angiotensin-converting Enzyme*

  2006cited by this paper
• Reinforcing effects of peripherally administered substance P and its C-terminal sequence pGlu6-SP6-11 in the rat

  2005cited by this paper
• Removal of cholinergic input to perirhinal cortex disrupts object recognition but not spatial working memory in the rat

  2005influential reference
• Angiotensin II blocks memory consolidation through an AT2 receptor-dependent mechanism

  2005cited by this paper
• Angiotensin-converting enzyme inhibition in cardiovascular disease: evidence with perindopril

  2005cited by this paper
• Effects of brain-penetrating ACE inhibitors on Alzheimer disease progression

  2004cited by this paper
• Perirhinal N-methyl-D-aspartate and muscarinic systems participate in object recognition in rats.

  2004cited by this paper
• Age‐Related Decline in Spatial Learning and Memory: Attenuation by Captopril

  2003cited by this paper
• Cholinergic neurotransmission is essential for perirhinal cortical plasticity and recognition memory.

  2003cited by this paper
• Pharmaceutical profiling method for lipophilicity and integrity using liquid chromatography-mass spectrometry.

  2003cited by this paper
• Angiotensin converting enzyme inhibition partially prevents deficits in water maze performance, hippocampal synaptic plasticity and cerebral blood flow in streptozotocin-diabetic rats

  2003cited by this paper
• Effects of blood pressure lowering with perindopril and indapamide therapy on dementia and cognitive decline in patients with cerebrovascular disease.

  2003influential reference
• The effect of n-3 polyunsaturated fatty acid-rich diets on cognitive and cerebrovascular parameters in chronic cerebral hypoperfusion.

  2002cited by this paper
• Cognitive impairment and chronic cerebral hypoperfusion: what can be learned from experimental models.

  2002cited by this paper
• ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.

  2001cited by this paper
• Facilitation of cholinergic transmission by substance P methyl ester in the mouse hippocampal slice preparation

  2000cited by this paper
• Substance P and its role in neural mechanisms governing learning, anxiety and functional recovery.

  2000cited by this paper
• Evaluation of high through-to-peak ratio of perindopril in SHR.

  1999cited by this paper
• Hypertension is related to cognitive impairment: a 20-year follow-up of 999 men.

  1998cited by this paper
• Effects of muscarinic blockade in perirhinal cortex during visual recognition.

  1997cited by this paper
• Facilitation of memory by peripheral administration of substance P.

  1997cited by this paper
• Release of cerebral acetylcholine increases during visually mediated behavior in monkeys

  1996cited by this paper
• Pharmacological studies on (4S)-1-methyl-3-[(2S)-2-[N-((1S)-1-ethoxycarbonyl-3-phenylpropyl)amino] propionyl]-2-oxo-imidazolidine-4-carboxylic acid hydrochloride (TA-6366), a new ACE inhibitor: I. ACE inhibitory and anti-hypertensive activities.

  1990cited by this paper
• Angiotensin II inhibits acetylcholine release from human temporal cortex: implications for cognition.

  1990cited by this paper
• [The effects of antihypertensive therapy on the quality of life].

  1989cited by this paper
• A new one-trial test for neurobiological studies of memory in rats. II: Effects of piracetam and pramiracetam.

  1989cited by this paper
• Angiotensin II inhibits the release of [3H]acetylcholine from rat entorhinal cortex in vitro.

  1989cited by this paper
• Hoe 288: Indications on the memory‐enhancing effects of a peptidase inhibitor

  1988cited by this paper
• The effects of antihypertensive therapy on the quality of life.

  1986cited by this paper
• Hydrolysis of substance p and neurotensin by converting enzyme and neutral endopeptidase.

  1984cited by this paper
• Carboxyl-terminal tripeptidyl hydrolysis of substance P by purified rabbit lung angiotensin-converting enzyme and the potentiation of substance P activity in vivo by captopril and MK-422.

  1984cited by this paper
• Elevation of Substance P‐like Immunoreactivity in Rat Central Nervous System by Protease Inhibitors

  1980cited by this paper

• Is The Renin-Angiotensin System A Friend or Foe in Neurological Diseases? Unveiling Its Role and Therapeutic Potential.

  2025cites this paper
• Current updates on latest basic research of scientific relevance in hypertensive dementia

  2025cites this paper
• Comparative Study on the Neuroprotective Effects of Perindopril and Benazepril in Experimentally-induced Chronic Mild Stress in Rats

  2025cites this paper
• The protective effects of Irbesartan in cognitive impairment in hypertension

  2024cites this paper
• The peptide Acein promotes dopamine secretion through clec-126 to extend the lifespan of elderly C. elegans

  2023cites this paper
• Therapeutic Implications of Renin–Angiotensin System Modulators in Alzheimer’s Dementia

  2023cites this paper
• Utilizing Proteomic Approaches to Uncover the Neuroprotective Effects of ACE Inhibitors: Implications for Alzheimer’s Disease Treatment

  2023cites this paper
• Pharmaceutical Potential of Casein-Derived Tripeptide Met-Lys-Pro: Improvement in Cognitive Impairments and Suppression of Inflammation in APP/PS1 Mice

  2022influential citation
• The effect of curcumin on blood pressure and cognitive impairment in spontaneously hypertensive rats

  2022cites this paper
• Effects of Antihypertensive Drugs on Cognitive Function in Elderly Patients with Hypertension: A Review

  2021cites this paper
• The use of angiotensin-converting enzyme inhibitors vs. angiotensin receptor blockers and cognitive decline in Alzheimer’s disease: the importance of blood-brain barrier penetration and APOE ε4 carrier status

  2021cites this paper
• Recent Advances in the Endogenous Brain Renin-Angiotensin System and Drugs Acting on It

  2021cites this paper
• Cognitive impairment in myocardial infarction and heart failure

  2021cites this paper
• Improvements of symptoms of Alzheimer`s disease by inhibition of the angiotensin system.

  2020cites this paper
• Rodent Models of Vascular Cognitive Impairment

  2020cites this paper
• Perindopril ameliorates experimental Alzheimer’s disease progression: role of amyloid β degradation, central estrogen receptor and hyperlipidemic-lipid raft signaling

  2020cites this paper
• Brain Vasculature and Cognition.

  2019cites this paper
• NEUROPEPTIDES AND OLIGOPEPTIDASES IN SCHIZOPHRENIA.

  2019cites this paper
• Exploiting Drug-Apolipoprotein E Gene Interactions in Hypertension to Preserve Cognitive Function: The 3-City Cohort Study.

  2019cites this paper
• Effects of Phytochemicals on Blood Pressure and Neuroprotection Mediated Via Brain Renin-Angiotensin System

  2019cites this paper
• The Protective Tributary Angiotensin Members of ReninAngiotensin System Display Beneficial Effects in the Central Nervous System Disorders

  2018cites this paper
• Effect of centrally acting angiotensin converting enzyme inhibitor on the exercise‐induced increases in muscle sympathetic nerve activity

  2018cites this paper
• Conjugation to Ascorbic Acid Enhances Brain Availability of Losartan Carboxylic Acid and Protects Against Parkinsonism in Rats

  2018cites this paper
• The study of effects of inhibition of the renin angiotensin system on memory in rats

  2018cites this paper
• The impact of currently recommended antihypertensive therapy on depression and other psychometric parameters: preliminary communication.

  2017cites this paper
• Stanowisko interdyscyplinarnego zespołu ekspertów dotyczące leczenia pacjentów z nadciśnieniem tętniczym i współistniejącymi zaburzeniami funkcji poznawczych w codziennej praktyce lekarskiej

  2017cites this paper
• Czy terapia nadciśnienia tętniczego może zmniejszyć ryzyko zaburzeń funkcji poznawczych i otępienia

  2017cites this paper
• Associations of centrally acting ACE inhibitors with cognitive decline and survival in Alzheimer’s disease

  2017cites this paper
• The possible role of advanced glycation endproducts (AGEs) in experimentally-induced ischemic brain damage.

  2017cites this paper
• P3‐096: Secondary Analyses of International Genomics of Alzheimer's Project Stage I GWAS Summary Data Identifies Additional Variants Associated With Late‐Onset Alzheimer's Disease

  2016cites this paper
• Telmisartan Modulates Glial Activation: In Vitro and In Vivo Studies

  2016cites this paper
• Small Molecule AngIV-based Analogs to Treat Alzheimers Disease

  2016cites this paper
• Tempol and perindopril protect against lipopolysaccharide-induced cognition impairment and amyloidogenesis by modulating brain-derived neurotropic factor, neuroinflammation and oxido-nitrosative stress

  2016cites this paper
• Cognitive Dysfunction and Dementia in Animal Models of Hypertension

  2016cites this paper
• Renin-angiotensin system as a potential therapeutic target in stroke and retinopathy: experimental and clinical evidence.

  2016cites this paper
• Renin-angiotensin system-targeting antihypertensive drugs and risk of vascular cognitive impairment: A meta-analysis.

  2016cites this paper
• Rodent Models of Vascular Cognitive Impairment

  2016cites this paper
• Hypertension and the Brain as an End-Organ Target

  2016cites this paper
• The novel nonapeptide acein targets angiotensin converting enzyme in the brain and induces dopamine release

  2016cites this paper
• The Brain Hepatocyte Growth Factor/c-Met Receptor System: A New Target for the Treatment of Alzheimer's Disease

  2015cites this paper
• ACE I/D genotype-related increase in ACE plasma activity is a better predictor for schizophrenia diagnosis than the genotype alone.

  2015cites this paper
• Perindopril increases the swallowing reflex by inhibiting substance P degradation and tyrosine hydroxylase activation in a rat model of dysphagia.

  2015cites this paper
• The implications of angiotensin-converting enzymes and their modulators in neurodegenerative disorders: current and future perspectives.

  2015cites this paper
• Convergent evidences from human and animal studies implicate angiotensin I-converting enzyme activity in cognitive performance in schizophrenia

  2015cites this paper
• Increasing complexity: which drug class to choose for treatment of hypertension in the elderly?

  2014cites this paper
• Effects of Centrally Acting Angiotensin Converting Enzyme Inhibitors on Functional Decline in Patients with Alzheimer's Disease

  2014cites this paper
• The effects of centrally acting ACE inhibitors on the rate of cognitive and functional decline in dementia: a KDD approach

  2014cites this paper
• Measurement-to-Measurement Blood Pressure Variability Is Related to Cognitive Performance: The Maine Syracuse Study

  2014cites this paper
• Renin Angiotensin Aldosterone System Inhibition in Controlling Dementia-Related Cognitive Decline

  2014cites this paper
• Increasing complexity: which drug class to choose for treatment of hypertension in the elderly?

  2014cites this paper
• Increasing complexity: which drug class to choose for treatment of hypertension in the elderly?

  2014cites this paper
• Increasing complexity: which drug class to choose for treatment of hypertension in the elderly?

  2014cites this paper
• Renin–angiotensin–aldosterone system has a pivotal role in cognitive impairment

  2013cites this paper
• Enalapril enhances the anticonvulsant activity of lamotrigine in the test of maximal electroshock

  2013cites this paper
• A Role for the Brain RAS in Alzheimer’s and Parkinson’s Diseases

  2013cites this paper
• The effects of perindopril on cognitive impairment induced by d-galactose and aluminum trichloride via inhibition of acetylcholinesterase activity and oxidative stress.

  2013cites this paper
• Effect of angiotensin II type 2 receptor on stroke, cognitive impairment and neurodegenerative diseases

  2013cites this paper
• Time until incident dementia among Medicare beneficiaries using centrally acting or non‐centrally acting ACE inhibitors

  2013cites this paper
• Enalapril protects endothelial cells against induced apoptosis in Alzheimer's disease

  2013cites this paper
• Hypertension and vascular dementia in the elderly: the potential role of anti-hypertensive agents

  2013cites this paper
• Angiotensin-(1-7) modulates renin-angiotensin system associated with reducing oxidative stress and attenuating neuronal apoptosis in the brain of hypertensive rats.

  2013cites this paper
• Roles of Brain Angiotensin II in Cognitive Function and Dementia

  2012cites this paper
• Mechanisms of chloride modulated activity in the C-domain of angiotensin-converting enzyme

  2012cites this paper
• Walking the Cognitive “Minefield” Between High and Low Blood Pressure

  2012cites this paper
• Lokalny układ renina-angiotensyna - nowy łącznik pomiędzy mózgiem a tarczycą?

  2011cites this paper